{
  "url": "https://dantelabs.com/ro/genes/camk2g",
  "gene": {
    "slug": "camk2g",
    "symbol": "CAMK2G",
    "name": "calcium/calmodulin dependent protein kinase II gamma",
    "hgnc": "HGNC:1463",
    "summary": null,
    "location": "10q22.2",
    "locusType": "gene with protein product",
    "aliases": [],
    "previousSymbols": [
      "CAMKG"
    ],
    "ensemblId": "ENSG00000148660",
    "entrezId": 818,
    "omim": [
      "602123"
    ],
    "uniprot": [
      "Q13555"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "10",
      "start": 73812501,
      "end": 73874555,
      "strand": "-",
      "ensemblTranscript": "ENST00000423381.6",
      "refseqTranscript": "NM_001367534.1",
      "ensemblProtein": "ENSP00000410298.3",
      "refseqProtein": "NP_001354463.1",
      "exons": [
        {
          "start": 73812501,
          "end": 73814505
        },
        {
          "start": 73815003,
          "end": 73815247
        },
        {
          "start": 73817023,
          "end": 73817117
        },
        {
          "start": 73817479,
          "end": 73817554
        },
        {
          "start": 73819532,
          "end": 73819645
        },
        {
          "start": 73821682,
          "end": 73821730
        },
        {
          "start": 73824040,
          "end": 73824084
        },
        {
          "start": 73825279,
          "end": 73825347
        },
        {
          "start": 73828089,
          "end": 73828121
        },
        {
          "start": 73837468,
          "end": 73837511
        },
        {
          "start": 73839539,
          "end": 73839601
        },
        {
          "start": 73842169,
          "end": 73842211
        },
        {
          "start": 73842458,
          "end": 73842541
        },
        {
          "start": 73847225,
          "end": 73847347
        },
        {
          "start": 73847988,
          "end": 73848082
        },
        {
          "start": 73848526,
          "end": 73848609
        },
        {
          "start": 73849013,
          "end": 73849115
        },
        {
          "start": 73849261,
          "end": 73849333
        },
        {
          "start": 73852254,
          "end": 73852319
        },
        {
          "start": 73853192,
          "end": 73853246
        },
        {
          "start": 73860830,
          "end": 73860889
        },
        {
          "start": 73872989,
          "end": 73873083
        },
        {
          "start": 73874397,
          "end": 73874555
        }
      ],
      "cds": {
        "start": 73815015,
        "end": 73874461
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "10",
      "start": 75572259,
      "end": 75634343,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 73343528,
      "end": 74343527,
      "genes": [
        {
          "symbol": "CFAP70",
          "ensemblId": "ENSG00000156042",
          "biotype": "protein_coding",
          "start": 73253762,
          "end": 73358868,
          "strand": "-",
          "slug": "cfap70"
        },
        {
          "symbol": "ANXA7",
          "ensemblId": "ENSG00000138279",
          "biotype": "protein_coding",
          "start": 73365027,
          "end": 73414731,
          "strand": "-",
          "slug": "anxa7"
        },
        {
          "symbol": "MSS51",
          "ensemblId": "ENSG00000166343",
          "biotype": "protein_coding",
          "start": 73423579,
          "end": 73433567,
          "strand": "-",
          "slug": "mss51"
        },
        {
          "symbol": "PPP3CB",
          "ensemblId": "ENSG00000107758",
          "biotype": "protein_coding",
          "start": 73436418,
          "end": 73496034,
          "strand": "-",
          "slug": "ppp3cb"
        },
        {
          "symbol": "USP54",
          "ensemblId": "ENSG00000166348",
          "biotype": "protein_coding",
          "start": 73497538,
          "end": 73626117,
          "strand": "-",
          "slug": "usp54"
        },
        {
          "symbol": "MYOZ1",
          "ensemblId": "ENSG00000177791",
          "biotype": "protein_coding",
          "start": 73631556,
          "end": 73642103,
          "strand": "-",
          "slug": "myoz1"
        },
        {
          "symbol": "SYNPO2L",
          "ensemblId": "ENSG00000166317",
          "biotype": "protein_coding",
          "start": 73644881,
          "end": 73663803,
          "strand": "-",
          "slug": "synpo2l"
        },
        {
          "symbol": "AGAP5",
          "ensemblId": "ENSG00000172650",
          "biotype": "protein_coding",
          "start": 73674276,
          "end": 73698109,
          "strand": "-",
          "slug": "agap5"
        },
        {
          "symbol": "SEC24C",
          "ensemblId": "ENSG00000176986",
          "biotype": "protein_coding",
          "start": 73744348,
          "end": 73772173,
          "strand": "+",
          "slug": "sec24c"
        },
        {
          "symbol": "POFUT4",
          "ensemblId": "ENSG00000196968",
          "biotype": "protein_coding",
          "start": 73772271,
          "end": 73780251,
          "strand": "+",
          "slug": "pofut4"
        },
        {
          "symbol": "CHCHD1",
          "ensemblId": "ENSG00000172586",
          "biotype": "protein_coding",
          "start": 73782039,
          "end": 73783652,
          "strand": "+",
          "slug": "chchd1"
        },
        {
          "symbol": "ZSWIM8",
          "ensemblId": "ENSG00000214655",
          "biotype": "protein_coding",
          "start": 73785549,
          "end": 73801797,
          "strand": "+",
          "slug": "zswim8"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000272916",
          "biotype": "protein_coding",
          "start": 73796514,
          "end": 73811651,
          "strand": "-"
        },
        {
          "symbol": "NDST2",
          "ensemblId": "ENSG00000166507",
          "biotype": "protein_coding",
          "start": 73801740,
          "end": 73811963,
          "strand": "-",
          "slug": "ndst2"
        },
        {
          "symbol": "PLAU",
          "ensemblId": "ENSG00000122861",
          "biotype": "protein_coding",
          "start": 73909177,
          "end": 73917501,
          "strand": "+",
          "slug": "plau"
        },
        {
          "symbol": "VCL",
          "ensemblId": "ENSG00000035403",
          "biotype": "protein_coding",
          "start": 73995193,
          "end": 74123073,
          "strand": "+",
          "slug": "vcl"
        },
        {
          "symbol": "AP3M1",
          "ensemblId": "ENSG00000185009",
          "biotype": "protein_coding",
          "start": 74120118,
          "end": 74151055,
          "strand": "-",
          "slug": "ap3m1"
        },
        {
          "symbol": "ADK",
          "ensemblId": "ENSG00000156110",
          "biotype": "protein_coding",
          "start": 74151185,
          "end": 74709963,
          "strand": "+",
          "slug": "adk"
        }
      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "intellectual-disability",
        "name": "Dizabilitate intelectuală",
        "diseases": [
          {
            "mondoId": "MONDO:0001071",
            "name": "dizabilitate intelectuală",
            "genes": 233,
            "inheritance": null,
            "description": null,
            "management": null,
            "evidence": {
              "gencc": [
                "G2P",
                "Labcorp Genetics (formerly Invitae)"
              ],
              "acmgSf": false,
              "inheritance": [
                "autosomal-dominant"
              ]
            },
            "sameAsReport": true,
            "broad": true
          }
        ],
        "url": "https://dantelabs.com/ro/conditions/intellectual-disability"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "macrocephaly",
        "name": "Big calvaria",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/macrocephaly"
      },
      {
        "slug": "fragile-nails",
        "name": "Brittle nails",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/fragile-nails"
      },
      {
        "slug": "long-palpebral-fissure",
        "name": "Broad opening between the eyelids",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/long-palpebral-fissure"
      },
      {
        "slug": "myopia",
        "name": "Close sighted",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/myopia"
      },
      {
        "slug": "strabismus",
        "name": "Cross-eyed",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/strabismus"
      },
      {
        "slug": "facial-hypotonia",
        "name": "Decreased facial muscle tone",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/facial-hypotonia"
      },
      {
        "slug": "delayed-speech-and-language-development",
        "name": "Delayed speech and language development",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/delayed-speech-and-language-development"
      },
      {
        "slug": "flat-face",
        "name": "Flat face",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/flat-face"
      },
      {
        "slug": "flat-forehead",
        "name": "Flat forehead",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "url": "https://dantelabs.com/traits/flat-forehead"
      },
      {
        "slug": "generalized-hypotonia",
        "name": "Generalized decreased muscle tone",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/generalized-hypotonia"
      },
      {
        "slug": "global-developmental-delay",
        "name": "Global developmental delay",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/global-developmental-delay"
      },
      {
        "slug": "high-forehead",
        "name": "High forehead",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "url": "https://dantelabs.com/traits/high-forehead"
      },
      {
        "slug": "highly-arched-eyebrow",
        "name": "Highly arched eyebrow",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/highly-arched-eyebrow"
      },
      {
        "slug": "severe-intellectual-disability",
        "name": "Intellectual disability, severe",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/severe-intellectual-disability"
      },
      {
        "slug": "long-philtrum",
        "name": "Long philtrum",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "url": "https://dantelabs.com/traits/long-philtrum"
      },
      {
        "slug": "low-set-ears",
        "name": "Low-set ears",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "url": "https://dantelabs.com/traits/low-set-ears"
      },
      {
        "slug": "mild-short-stature",
        "name": "Mild short stature",
        "systems": [
          "growth-abnormality"
        ],
        "url": "https://dantelabs.com/traits/mild-short-stature"
      },
      {
        "slug": "narrow-forehead",
        "name": "Narrow forehead",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/narrow-forehead"
      },
      {
        "slug": "poor-speech",
        "name": "Poor speech",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/poor-speech"
      },
      {
        "slug": "protruding-ear",
        "name": "Prominent ear",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "url": "https://dantelabs.com/traits/protruding-ear"
      },
      {
        "slug": "self-mutilation",
        "name": "Self-mutilation",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/self-mutilation"
      },
      {
        "slug": "brachydactyly",
        "name": "Short fingers or toes",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/brachydactyly"
      },
      {
        "slug": "short-foot",
        "name": "Short foot",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/short-foot"
      },
      {
        "slug": "short-palm",
        "name": "Short palm",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/short-palm"
      },
      {
        "slug": "short-stature",
        "name": "Short stature",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/short-stature"
      },
      {
        "slug": "sacral-dimple",
        "name": "Spinal dimple",
        "systems": [
          "abnormality-of-the-integument",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/sacral-dimple"
      }
    ],
    "related": [
      {
        "slug": "acsl4",
        "symbol": "ACSL4",
        "name": "acyl-CoA synthetase long chain family member 4",
        "shared": 1,
        "url": "https://dantelabs.com/ro/genes/acsl4"
      },
      {
        "slug": "adk",
        "symbol": "ADK",
        "name": "adenosine kinase",
        "shared": 1,
        "url": "https://dantelabs.com/ro/genes/adk"
      },
      {
        "slug": "adnp",
        "symbol": "ADNP",
        "name": "activity dependent neuroprotector homeobox",
        "shared": 1,
        "url": "https://dantelabs.com/ro/genes/adnp"
      },
      {
        "slug": "aff2",
        "symbol": "AFF2",
        "name": "ALF transcription elongation factor 2",
        "shared": 1,
        "url": "https://dantelabs.com/ro/genes/aff2"
      },
      {
        "slug": "ahdc1",
        "symbol": "AHDC1",
        "name": "AT-hook DNA binding motif containing 1",
        "shared": 1,
        "url": "https://dantelabs.com/ro/genes/ahdc1"
      },
      {
        "slug": "alkbh8",
        "symbol": "ALKBH8",
        "name": "alkB homolog 8, tRNA methyltransferase",
        "shared": 1,
        "url": "https://dantelabs.com/ro/genes/alkbh8"
      },
      {
        "slug": "ank3",
        "symbol": "ANK3",
        "name": "ankyrin 3",
        "shared": 1,
        "url": "https://dantelabs.com/ro/genes/ank3"
      },
      {
        "slug": "ankrd11",
        "symbol": "ANKRD11",
        "name": "ankyrin repeat domain 11",
        "shared": 1,
        "url": "https://dantelabs.com/ro/genes/ankrd11"
      },
      {
        "slug": "ap1s2",
        "symbol": "AP1S2",
        "name": "adaptor related protein complex 1 subunit sigma 2",
        "shared": 1,
        "url": "https://dantelabs.com/ro/genes/ap1s2"
      },
      {
        "slug": "ap2m1",
        "symbol": "AP2M1",
        "name": "adaptor related protein complex 2 subunit mu 1",
        "shared": 1,
        "url": "https://dantelabs.com/ro/genes/ap2m1"
      },
      {
        "slug": "arhgef9",
        "symbol": "ARHGEF9",
        "name": "Cdc42 guanine nucleotide exchange factor 9",
        "shared": 1,
        "url": "https://dantelabs.com/ro/genes/arhgef9"
      },
      {
        "slug": "arid1a",
        "symbol": "ARID1A",
        "name": "AT-rich interaction domain 1A",
        "shared": 1,
        "url": "https://dantelabs.com/ro/genes/arid1a"
      }
    ],
    "sources": {
      "bundleId": "2026.10.18-8b139e39",
      "panel": "2026-10-18",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}