{
  "url": "https://dantelabs.com/traits/pneumonia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "pneumonia",
    "id": "HP:0002090",
    "name": "Pneumonia",
    "definition": "Inflammation of any part of the lung parenchyma.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      },
      {
        "slug": "abnormality-of-the-respiratory-system",
        "name": "Abnormality of the respiratory system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-respiratory-system"
      }
    ],
    "broader": [
      {
        "slug": "increased-inflammatory-response",
        "name": "Increased inflammatory response",
        "url": "https://dantelabs.com/traits/increased-inflammatory-response"
      },
      {
        "slug": "unusual-lower-respiratory-tract-infection",
        "name": "Unusual lower respiratory tract infection",
        "url": "https://dantelabs.com/traits/unusual-lower-respiratory-tract-infection"
      }
    ],
    "narrower": [
      {
        "slug": "recurrent-pneumonia",
        "name": "Recurrent pneumonia",
        "genes": 159,
        "url": "https://dantelabs.com/traits/recurrent-pneumonia"
      },
      {
        "slug": "aspiration-pneumonia",
        "name": "Aspiration pneumonia",
        "genes": 74,
        "url": "https://dantelabs.com/traits/aspiration-pneumonia"
      },
      {
        "slug": "acute-infectious-pneumonia",
        "name": "Acute infectious pneumonia",
        "genes": 6,
        "url": "https://dantelabs.com/traits/acute-infectious-pneumonia"
      }
    ],
    "genes": [
      {
        "slug": "casp8",
        "symbol": "CASP8",
        "hgnc": "HGNC:1509",
        "name": "caspase 8",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/casp8"
      },
      {
        "slug": "cfap54",
        "symbol": "CFAP54",
        "hgnc": "HGNC:26456",
        "name": "cilia and flagella associated protein 54",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap54"
      },
      {
        "slug": "cilk1",
        "symbol": "CILK1",
        "hgnc": "HGNC:21219",
        "name": "ciliogenesis associated kinase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cilk1"
      },
      {
        "slug": "copz1",
        "symbol": "COPZ1",
        "hgnc": "HGNC:2243",
        "name": "coat protein complex I subunit zeta 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/copz1"
      },
      {
        "slug": "ctsa",
        "symbol": "CTSA",
        "hgnc": "HGNC:9251",
        "name": "cathepsin A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ctsa"
      },
      {
        "slug": "dclre1c",
        "symbol": "DCLRE1C",
        "hgnc": "HGNC:17642",
        "name": "DNA cross-link repair 1C",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/dclre1c"
      },
      {
        "slug": "dnm1l",
        "symbol": "DNM1L",
        "hgnc": "HGNC:2973",
        "name": "dynamin 1L",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnm1l"
      },
      {
        "slug": "epg5",
        "symbol": "EPG5",
        "hgnc": "HGNC:29331",
        "name": "ectopic P-granules 5 autophagy tethering factor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/epg5"
      },
      {
        "slug": "fancf",
        "symbol": "FANCF",
        "hgnc": "HGNC:3587",
        "name": "FA complementation group F",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancf"
      },
      {
        "slug": "icoslg",
        "symbol": "ICOSLG",
        "hgnc": "HGNC:17087",
        "name": "inducible T cell costimulator ligand",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/icoslg"
      },
      {
        "slug": "ikbkg",
        "symbol": "IKBKG",
        "hgnc": "HGNC:5961",
        "name": "inhibitor of nuclear factor kappa B kinase regulatory subunit gamma",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ikbkg"
      },
      {
        "slug": "irf1",
        "symbol": "IRF1",
        "hgnc": "HGNC:6116",
        "name": "interferon regulatory factor 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/irf1"
      },
      {
        "slug": "itpr3",
        "symbol": "ITPR3",
        "hgnc": "HGNC:6182",
        "name": "inositol 1,4,5-trisphosphate receptor type 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/itpr3"
      },
      {
        "slug": "jak3",
        "symbol": "JAK3",
        "hgnc": "HGNC:6193",
        "name": "Janus kinase 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/jak3"
      },
      {
        "slug": "kdm6b",
        "symbol": "KDM6B",
        "hgnc": "HGNC:29012",
        "name": "lysine demethylase 6B",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdm6b"
      },
      {
        "slug": "lrba",
        "symbol": "LRBA",
        "hgnc": "HGNC:1742",
        "name": "LPS responsive beige-like anchor protein",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrba"
      },
      {
        "slug": "mcidas",
        "symbol": "MCIDAS",
        "hgnc": "HGNC:40050",
        "name": "multiciliate differentiation and DNA synthesis associated cell cycle protein",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mcidas"
      },
      {
        "slug": "mdga2",
        "symbol": "MDGA2",
        "hgnc": "HGNC:19835",
        "name": "MAM domain containing glycosylphosphatidylinositol anchor 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mdga2"
      },
      {
        "slug": "nbn",
        "symbol": "NBN",
        "hgnc": "HGNC:7652",
        "name": "nibrin",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nbn"
      },
      {
        "slug": "nhej1",
        "symbol": "NHEJ1",
        "hgnc": "HGNC:25737",
        "name": "non-homologous end joining factor 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nhej1"
      },
      {
        "slug": "piga",
        "symbol": "PIGA",
        "hgnc": "HGNC:8957",
        "name": "phosphatidylinositol glycan anchor biosynthesis class A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/piga"
      },
      {
        "slug": "ppfia3",
        "symbol": "PPFIA3",
        "hgnc": "HGNC:9247",
        "name": "PPFI scaffold protein A3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppfia3"
      },
      {
        "slug": "rag1",
        "symbol": "RAG1",
        "hgnc": "HGNC:9831",
        "name": "recombination activating 1",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/rag1"
      },
      {
        "slug": "rag2",
        "symbol": "RAG2",
        "hgnc": "HGNC:9832",
        "name": "recombination activating 2",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/rag2"
      },
      {
        "slug": "rel",
        "symbol": "REL",
        "hgnc": "HGNC:9954",
        "name": "REL proto-oncogene, NF-kB subunit",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rel"
      },
      {
        "slug": "rtn2",
        "symbol": "RTN2",
        "hgnc": "HGNC:10468",
        "name": "reticulon 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rtn2"
      },
      {
        "slug": "sec61a1",
        "symbol": "SEC61A1",
        "hgnc": "HGNC:18276",
        "name": "SEC61 translocon subunit alpha 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sec61a1"
      },
      {
        "slug": "dock8",
        "symbol": "DOCK8",
        "hgnc": "HGNC:19191",
        "name": "dedicator of cytokinesis 8",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dock8"
      },
      {
        "slug": "il2rg",
        "symbol": "IL2RG",
        "hgnc": "HGNC:6010",
        "name": "interleukin 2 receptor subunit gamma",
        "frequency": "very-frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/il2rg"
      },
      {
        "slug": "slc35a1",
        "symbol": "SLC35A1",
        "hgnc": "HGNC:11021",
        "name": "solute carrier family 35 member A1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc35a1"
      },
      {
        "slug": "acta1",
        "symbol": "ACTA1",
        "hgnc": "HGNC:129",
        "name": "actin alpha 1, skeletal muscle",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/acta1"
      },
      {
        "slug": "ada",
        "symbol": "ADA",
        "hgnc": "HGNC:186",
        "name": "adenosine deaminase",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ada"
      },
      {
        "slug": "arsb",
        "symbol": "ARSB",
        "hgnc": "HGNC:714",
        "name": "arylsulfatase B",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arsb"
      },
      {
        "slug": "card11",
        "symbol": "CARD11",
        "hgnc": "HGNC:16393",
        "name": "caspase recruitment domain family member 11",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/card11"
      },
      {
        "slug": "chd7",
        "symbol": "CHD7",
        "hgnc": "HGNC:20626",
        "name": "chromodomain helicase DNA binding protein 7",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chd7"
      },
      {
        "slug": "clpb",
        "symbol": "CLPB",
        "hgnc": "HGNC:30664",
        "name": "ClpB family mitochondrial disaggregase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/clpb"
      },
      {
        "slug": "ctla4",
        "symbol": "CTLA4",
        "hgnc": "HGNC:2505",
        "name": "cytotoxic T-lymphocyte associated protein 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ctla4"
      },
      {
        "slug": "cxcr4",
        "symbol": "CXCR4",
        "hgnc": "HGNC:2561",
        "name": "C-X-C motif chemokine receptor 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cxcr4"
      },
      {
        "slug": "elane",
        "symbol": "ELANE",
        "hgnc": "HGNC:3309",
        "name": "elastase, neutrophil expressed",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/elane"
      },
      {
        "slug": "fcgr3b",
        "symbol": "FCGR3B",
        "hgnc": "HGNC:3620",
        "name": "Fc gamma receptor IIIb",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fcgr3b"
      },
      {
        "slug": "foxn1",
        "symbol": "FOXN1",
        "hgnc": "HGNC:12765",
        "name": "forkhead box N1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/foxn1"
      },
      {
        "slug": "gfi1",
        "symbol": "GFI1",
        "hgnc": "HGNC:4237",
        "name": "growth factor independent 1 transcriptional repressor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gfi1"
      },
      {
        "slug": "il7r",
        "symbol": "IL7R",
        "hgnc": "HGNC:6024",
        "name": "interleukin 7 receptor",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/il7r"
      },
      {
        "slug": "man2b1",
        "symbol": "MAN2B1",
        "hgnc": "HGNC:6826",
        "name": "mannosidase alpha class 2B member 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/man2b1"
      },
      {
        "slug": "mtm1",
        "symbol": "MTM1",
        "hgnc": "HGNC:7448",
        "name": "myotubularin 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mtm1"
      },
      {
        "slug": "nudcd3",
        "symbol": "NUDCD3",
        "hgnc": "HGNC:22208",
        "name": "NudC domain containing 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nudcd3"
      },
      {
        "slug": "polr3a",
        "symbol": "POLR3A",
        "hgnc": "HGNC:30074",
        "name": "RNA polymerase III subunit A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/polr3a"
      },
      {
        "slug": "psmb10",
        "symbol": "PSMB10",
        "hgnc": "HGNC:9538",
        "name": "proteasome 20S subunit beta 10",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/psmb10"
      },
      {
        "slug": "psmb9",
        "symbol": "PSMB9",
        "hgnc": "HGNC:9546",
        "name": "proteasome 20S subunit beta 9",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/psmb9"
      },
      {
        "slug": "rfx5",
        "symbol": "RFX5",
        "hgnc": "HGNC:9986",
        "name": "regulatory factor X5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rfx5"
      },
      {
        "slug": "rmrp",
        "symbol": "RMRP",
        "hgnc": "HGNC:10031",
        "name": "RNA component of mitochondrial RNA processing endoribonuclease",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rmrp"
      },
      {
        "slug": "rnf168",
        "symbol": "RNF168",
        "hgnc": "HGNC:26661",
        "name": "ring finger protein 168",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnf168"
      },
      {
        "slug": "selenon",
        "symbol": "SELENON",
        "hgnc": "HGNC:15999",
        "name": "selenoprotein N",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/selenon"
      },
      {
        "slug": "spink5",
        "symbol": "SPINK5",
        "hgnc": "HGNC:15464",
        "name": "serine peptidase inhibitor Kazal type 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spink5"
      },
      {
        "slug": "srp19",
        "symbol": "SRP19",
        "hgnc": "HGNC:11300",
        "name": "signal recognition particle 19",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/srp19"
      },
      {
        "slug": "syk",
        "symbol": "SYK",
        "hgnc": "HGNC:11491",
        "name": "spleen associated tyrosine kinase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/syk"
      },
      {
        "slug": "tcirg1",
        "symbol": "TCIRG1",
        "hgnc": "HGNC:11647",
        "name": "T cell immune regulator 1, ATPase H+ transporting V0 subunit a3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tcirg1"
      },
      {
        "slug": "zap70",
        "symbol": "ZAP70",
        "hgnc": "HGNC:12858",
        "name": "zeta chain of T cell receptor associated protein kinase 70",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/zap70"
      },
      {
        "slug": "abca3",
        "symbol": "ABCA3",
        "hgnc": "HGNC:33",
        "name": "ATP binding cassette subfamily A member 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/abca3"
      },
      {
        "slug": "blm",
        "symbol": "BLM",
        "hgnc": "HGNC:1058",
        "name": "BLM RecQ like helicase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/blm"
      },
      {
        "slug": "borcs5",
        "symbol": "BORCS5",
        "hgnc": "HGNC:17950",
        "name": "BLOC-1 related complex subunit 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/borcs5"
      },
      {
        "slug": "cacna1c",
        "symbol": "CACNA1C",
        "hgnc": "HGNC:1390",
        "name": "calcium voltage-gated channel subunit alpha1 C",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacna1c"
      },
      {
        "slug": "cd247",
        "symbol": "CD247",
        "hgnc": "HGNC:1677",
        "name": "CD247 molecule",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cd247"
      },
      {
        "slug": "cd3d",
        "symbol": "CD3D",
        "hgnc": "HGNC:1673",
        "name": "CD3 delta subunit of T-cell receptor complex",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cd3d"
      },
      {
        "slug": "cd3e",
        "symbol": "CD3E",
        "hgnc": "HGNC:1674",
        "name": "CD3 epsilon subunit of T-cell receptor complex",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cd3e"
      },
      {
        "slug": "crebbp",
        "symbol": "CREBBP",
        "hgnc": "HGNC:2348",
        "name": "CREB binding lysine acetyltransferase",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/crebbp"
      },
      {
        "slug": "dnajc21",
        "symbol": "DNAJC21",
        "hgnc": "HGNC:27030",
        "name": "DnaJ heat shock protein family (Hsp40) member C21",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnajc21"
      },
      {
        "slug": "efl1",
        "symbol": "EFL1",
        "hgnc": "HGNC:25789",
        "name": "elongation factor like GTPase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/efl1"
      },
      {
        "slug": "ep300",
        "symbol": "EP300",
        "hgnc": "HGNC:3373",
        "name": "EP300 lysine acetyltransferase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ep300"
      },
      {
        "slug": "focad",
        "symbol": "FOCAD",
        "hgnc": "HGNC:23377",
        "name": "focadhesin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/focad"
      },
      {
        "slug": "ifih1",
        "symbol": "IFIH1",
        "hgnc": "HGNC:18873",
        "name": "interferon induced with helicase C domain 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ifih1"
      },
      {
        "slug": "ighg2",
        "symbol": "IGHG2",
        "hgnc": "HGNC:5526",
        "name": "immunoglobulin heavy constant gamma 2 (G2m marker)",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ighg2"
      },
      {
        "slug": "igkc",
        "symbol": "IGKC",
        "hgnc": "HGNC:5716",
        "name": "immunoglobulin kappa constant",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/igkc"
      },
      {
        "slug": "il12rb1",
        "symbol": "IL12RB1",
        "hgnc": "HGNC:5971",
        "name": "interleukin 12 receptor subunit beta 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/il12rb1"
      },
      {
        "slug": "il17ra",
        "symbol": "IL17RA",
        "hgnc": "HGNC:5985",
        "name": "interleukin 17 receptor A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/il17ra"
      },
      {
        "slug": "lama3",
        "symbol": "LAMA3",
        "hgnc": "HGNC:6483",
        "name": "laminin subunit alpha 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lama3"
      },
      {
        "slug": "lamb3",
        "symbol": "LAMB3",
        "hgnc": "HGNC:6490",
        "name": "laminin subunit beta 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lamb3"
      },
      {
        "slug": "lamc2",
        "symbol": "LAMC2",
        "hgnc": "HGNC:6493",
        "name": "laminin subunit gamma 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lamc2"
      },
      {
        "slug": "ryr1",
        "symbol": "RYR1",
        "hgnc": "HGNC:10483",
        "name": "ryanodine receptor 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ryr1"
      },
      {
        "slug": "sbds",
        "symbol": "SBDS",
        "hgnc": "HGNC:19440",
        "name": "SBDS ribosome maturation factor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sbds"
      },
      {
        "slug": "sftpb",
        "symbol": "SFTPB",
        "hgnc": "HGNC:10801",
        "name": "surfactant protein B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sftpb"
      },
      {
        "slug": "sftpc",
        "symbol": "SFTPC",
        "hgnc": "HGNC:10802",
        "name": "surfactant protein C",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sftpc"
      },
      {
        "slug": "sgcg",
        "symbol": "SGCG",
        "hgnc": "HGNC:10809",
        "name": "sarcoglycan gamma",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sgcg"
      },
      {
        "slug": "trex1",
        "symbol": "TREX1",
        "hgnc": "HGNC:12269",
        "name": "three prime repair exonuclease 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trex1"
      },
      {
        "slug": "znf699",
        "symbol": "ZNF699",
        "hgnc": "HGNC:24750",
        "name": "zinc finger protein 699",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znf699"
      },
      {
        "slug": "acadvl",
        "symbol": "ACADVL",
        "hgnc": "HGNC:92",
        "name": "acyl-CoA dehydrogenase very long chain",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/acadvl"
      },
      {
        "slug": "acp5",
        "symbol": "ACP5",
        "hgnc": "HGNC:124",
        "name": "acid phosphatase 5, tartrate resistant",
        "frequency": "very-rare",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/acp5"
      },
      {
        "slug": "actc1",
        "symbol": "ACTC1",
        "hgnc": "HGNC:143",
        "name": "actin alpha cardiac muscle 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/actc1"
      },
      {
        "slug": "aldh3a2",
        "symbol": "ALDH3A2",
        "hgnc": "HGNC:403",
        "name": "aldehyde dehydrogenase 3 family member A2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aldh3a2"
      },
      {
        "slug": "cited2",
        "symbol": "CITED2",
        "hgnc": "HGNC:1987",
        "name": "Cbp/p300 interacting transactivator with ED-rich tail 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cited2"
      },
      {
        "slug": "foxp3",
        "symbol": "FOXP3",
        "hgnc": "HGNC:6106",
        "name": "forkhead box P3",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/foxp3"
      },
      {
        "slug": "gata4",
        "symbol": "GATA4",
        "hgnc": "HGNC:4173",
        "name": "GATA binding protein 4",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gata4"
      },
      {
        "slug": "gata6",
        "symbol": "GATA6",
        "hgnc": "HGNC:4174",
        "name": "GATA binding protein 6",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gata6"
      },
      {
        "slug": "myh6",
        "symbol": "MYH6",
        "hgnc": "HGNC:7576",
        "name": "myosin heavy chain 6",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myh6"
      },
      {
        "slug": "nkx2-5",
        "symbol": "NKX2-5",
        "hgnc": "HGNC:2488",
        "name": "NK2 homeobox 5",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nkx2-5"
      },
      {
        "slug": "tbx20",
        "symbol": "TBX20",
        "hgnc": "HGNC:11598",
        "name": "T-box transcription factor 20",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbx20"
      },
      {
        "slug": "tll1",
        "symbol": "TLL1",
        "hgnc": "HGNC:11843",
        "name": "tolloid like 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tll1"
      },
      {
        "slug": "btk",
        "symbol": "BTK",
        "hgnc": "HGNC:1133",
        "name": "Bruton tyrosine kinase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/btk"
      },
      {
        "slug": "cfb",
        "symbol": "CFB",
        "hgnc": "HGNC:1037",
        "name": "complement factor B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfb"
      },
      {
        "slug": "dnai1",
        "symbol": "DNAI1",
        "hgnc": "HGNC:2954",
        "name": "dynein axonemal intermediate chain 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnai1"
      },
      {
        "slug": "dnai2",
        "symbol": "DNAI2",
        "hgnc": "HGNC:18744",
        "name": "dynein axonemal intermediate chain 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnai2"
      },
      {
        "slug": "dnmt3b",
        "symbol": "DNMT3B",
        "hgnc": "HGNC:2979",
        "name": "DNA methyltransferase 3 beta",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnmt3b"
      },
      {
        "slug": "icos",
        "symbol": "ICOS",
        "hgnc": "HGNC:5351",
        "name": "inducible T cell costimulator",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/icos"
      },
      {
        "slug": "ifngr1",
        "symbol": "IFNGR1",
        "hgnc": "HGNC:5439",
        "name": "interferon gamma receptor 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ifngr1"
      },
      {
        "slug": "irf8",
        "symbol": "IRF8",
        "hgnc": "HGNC:5358",
        "name": "interferon regulatory factor 8",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/irf8"
      },
      {
        "slug": "knstrn",
        "symbol": "KNSTRN",
        "hgnc": "HGNC:30767",
        "name": "kinetochore localized astrin (SPAG5) binding protein",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/knstrn"
      },
      {
        "slug": "ltbp3",
        "symbol": "LTBP3",
        "hgnc": "HGNC:6716",
        "name": "latent transforming growth factor beta binding protein 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ltbp3"
      },
      {
        "slug": "nipbl",
        "symbol": "NIPBL",
        "hgnc": "HGNC:28862",
        "name": "NIPBL cohesin loading factor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nipbl"
      },
      {
        "slug": "pik3cd",
        "symbol": "PIK3CD",
        "hgnc": "HGNC:8977",
        "name": "phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pik3cd"
      },
      {
        "slug": "pnp",
        "symbol": "PNP",
        "hgnc": "HGNC:7892",
        "name": "purine nucleoside phosphorylase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pnp"
      },
      {
        "slug": "ranbp2",
        "symbol": "RANBP2",
        "hgnc": "HGNC:9848",
        "name": "RAN binding protein 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ranbp2"
      },
      {
        "slug": "slc35c1",
        "symbol": "SLC35C1",
        "hgnc": "HGNC:20197",
        "name": "solute carrier family 35 member C1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc35c1"
      },
      {
        "slug": "srebf1",
        "symbol": "SREBF1",
        "hgnc": "HGNC:11289",
        "name": "sterol regulatory element binding transcription factor 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/srebf1"
      },
      {
        "slug": "zbtb24",
        "symbol": "ZBTB24",
        "hgnc": "HGNC:21143",
        "name": "zinc finger and BTB domain containing 24",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zbtb24"
      }
    ]
  }
}