{
  "url": "https://dantelabs.com/traits/hirsutism",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "hirsutism",
    "id": "HP:0001007",
    "name": "Excessive hairiness",
    "label": "Hirsutism",
    "definition": "Abnormally increased hair growth referring to a male pattern of body hair (androgenic hair).",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-hair-quantity",
        "name": "Abnormal hair quantity",
        "url": "https://dantelabs.com/traits/abnormal-hair-quantity"
      }
    ],
    "narrower": [
      {
        "slug": "generalized-hirsutism",
        "name": "Excessive hairiness over body",
        "genes": 89,
        "url": "https://dantelabs.com/traits/generalized-hirsutism"
      },
      {
        "slug": "localized-hirsutism",
        "name": "Localized abnormal hair growth",
        "genes": 0,
        "url": "https://dantelabs.com/traits/localized-hirsutism"
      }
    ],
    "genes": [
      {
        "slug": "alpk3",
        "symbol": "ALPK3",
        "hgnc": "HGNC:17574",
        "name": "alpha kinase 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alpk3"
      },
      {
        "slug": "arid1a",
        "symbol": "ARID1A",
        "hgnc": "HGNC:11110",
        "name": "AT-rich interaction domain 1A",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/arid1a"
      },
      {
        "slug": "bmp15",
        "symbol": "BMP15",
        "hgnc": "HGNC:1068",
        "name": "bone morphogenetic protein 15",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bmp15"
      },
      {
        "slug": "cdk5",
        "symbol": "CDK5",
        "hgnc": "HGNC:1774",
        "name": "cyclin dependent kinase 5",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdk5"
      },
      {
        "slug": "eif4a2",
        "symbol": "EIF4A2",
        "hgnc": "HGNC:3284",
        "name": "eukaryotic translation initiation factor 4A2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eif4a2"
      },
      {
        "slug": "emc10",
        "symbol": "EMC10",
        "hgnc": "HGNC:27609",
        "name": "ER membrane protein complex subunit 10",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/emc10"
      },
      {
        "slug": "fgfr2",
        "symbol": "FGFR2",
        "hgnc": "HGNC:3689",
        "name": "fibroblast growth factor receptor 2",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/fgfr2"
      },
      {
        "slug": "hdac8",
        "symbol": "HDAC8",
        "hgnc": "HGNC:13315",
        "name": "histone deacetylase 8",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hdac8"
      },
      {
        "slug": "inpp4a",
        "symbol": "INPP4A",
        "hgnc": "HGNC:6074",
        "name": "inositol polyphosphate-4-phosphatase type I A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/inpp4a"
      },
      {
        "slug": "insr",
        "symbol": "INSR",
        "hgnc": "HGNC:6091",
        "name": "insulin receptor",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/insr"
      },
      {
        "slug": "mab21l1",
        "symbol": "MAB21L1",
        "hgnc": "HGNC:6757",
        "name": "mab-21 like 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/mab21l1"
      },
      {
        "slug": "map1b",
        "symbol": "MAP1B",
        "hgnc": "HGNC:6836",
        "name": "microtubule associated protein 1B",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/map1b"
      },
      {
        "slug": "mau2",
        "symbol": "MAU2",
        "hgnc": "HGNC:29140",
        "name": "MAU2 sister chromatid cohesion factor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mau2"
      },
      {
        "slug": "mmp2",
        "symbol": "MMP2",
        "hgnc": "HGNC:7166",
        "name": "matrix metallopeptidase 2",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/mmp2"
      },
      {
        "slug": "ofd1",
        "symbol": "OFD1",
        "hgnc": "HGNC:2567",
        "name": "OFD1 centriole and centriolar satellite protein",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ofd1"
      },
      {
        "slug": "plaat3",
        "symbol": "PLAAT3",
        "hgnc": "HGNC:17825",
        "name": "phospholipase A and acyltransferase 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/plaat3"
      },
      {
        "slug": "pum1",
        "symbol": "PUM1",
        "hgnc": "HGNC:14957",
        "name": "pumilio RNA binding family member 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pum1"
      },
      {
        "slug": "taf6",
        "symbol": "TAF6",
        "hgnc": "HGNC:11540",
        "name": "TATA-box binding protein associated factor 6",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/taf6"
      },
      {
        "slug": "uggt1",
        "symbol": "UGGT1",
        "hgnc": "HGNC:15663",
        "name": "UDP-glucose glycoprotein glucosyltransferase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/uggt1"
      },
      {
        "slug": "abca5",
        "symbol": "ABCA5",
        "hgnc": "HGNC:35",
        "name": "ATP binding cassette subfamily A member 5",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/abca5"
      },
      {
        "slug": "arsb",
        "symbol": "ARSB",
        "hgnc": "HGNC:714",
        "name": "arylsulfatase B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arsb"
      },
      {
        "slug": "crebbp",
        "symbol": "CREBBP",
        "hgnc": "HGNC:2348",
        "name": "CREB binding lysine acetyltransferase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/crebbp"
      },
      {
        "slug": "ep300",
        "symbol": "EP300",
        "hgnc": "HGNC:3373",
        "name": "EP300 lysine acetyltransferase",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ep300"
      },
      {
        "slug": "fshr",
        "symbol": "FSHR",
        "hgnc": "HGNC:3969",
        "name": "follicle stimulating hormone receptor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fshr"
      },
      {
        "slug": "mmp14",
        "symbol": "MMP14",
        "hgnc": "HGNC:7160",
        "name": "matrix metallopeptidase 14",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/mmp14"
      },
      {
        "slug": "nr3c1",
        "symbol": "NR3C1",
        "hgnc": "HGNC:7978",
        "name": "nuclear receptor subfamily 3 group C member 1",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/nr3c1"
      },
      {
        "slug": "rin2",
        "symbol": "RIN2",
        "hgnc": "HGNC:18750",
        "name": "Ras and Rab interactor 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rin2"
      },
      {
        "slug": "smc3",
        "symbol": "SMC3",
        "hgnc": "HGNC:2468",
        "name": "structural maintenance of chromosomes 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smc3"
      },
      {
        "slug": "ube2a",
        "symbol": "UBE2A",
        "hgnc": "HGNC:12472",
        "name": "ubiquitin conjugating enzyme E2 A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ube2a"
      },
      {
        "slug": "wnt4",
        "symbol": "WNT4",
        "hgnc": "HGNC:12783",
        "name": "Wnt family member 4",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/wnt4"
      },
      {
        "slug": "adamts2",
        "symbol": "ADAMTS2",
        "hgnc": "HGNC:218",
        "name": "ADAM metallopeptidase with thrombospondin type 1 motif 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/adamts2"
      },
      {
        "slug": "aimp2",
        "symbol": "AIMP2",
        "hgnc": "HGNC:20609",
        "name": "aminoacyl tRNA synthetase complex interacting multifunctional protein 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aimp2"
      },
      {
        "slug": "arid1b",
        "symbol": "ARID1B",
        "hgnc": "HGNC:18040",
        "name": "AT-rich interaction domain 1B",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arid1b"
      },
      {
        "slug": "arid2",
        "symbol": "ARID2",
        "hgnc": "HGNC:18037",
        "name": "AT-rich interaction domain 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arid2"
      },
      {
        "slug": "armc5",
        "symbol": "ARMC5",
        "hgnc": "HGNC:25781",
        "name": "armadillo repeat containing 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/armc5"
      },
      {
        "slug": "atp6v1b2",
        "symbol": "ATP6V1B2",
        "hgnc": "HGNC:854",
        "name": "ATPase H+ transporting V1 subunit B2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp6v1b2"
      },
      {
        "slug": "atrx",
        "symbol": "ATRX",
        "hgnc": "HGNC:886",
        "name": "ATRX chromatin remodeler",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atrx"
      },
      {
        "slug": "braf",
        "symbol": "BRAF",
        "hgnc": "HGNC:1097",
        "name": "B-Raf proto-oncogene, serine/threonine kinase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/braf"
      },
      {
        "slug": "cdh23",
        "symbol": "CDH23",
        "hgnc": "HGNC:13733",
        "name": "cadherin related 23",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdh23"
      },
      {
        "slug": "cnot2",
        "symbol": "CNOT2",
        "hgnc": "HGNC:7878",
        "name": "CCR4-NOT transcription complex subunit 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cnot2"
      },
      {
        "slug": "copb1",
        "symbol": "COPB1",
        "hgnc": "HGNC:2231",
        "name": "coat protein complex I subunit beta 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/copb1"
      },
      {
        "slug": "cyp11b1",
        "symbol": "CYP11B1",
        "hgnc": "HGNC:2591",
        "name": "cytochrome P450 family 11 subfamily B member 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cyp11b1"
      },
      {
        "slug": "dpf2",
        "symbol": "DPF2",
        "hgnc": "HGNC:9964",
        "name": "double PHD fingers 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dpf2"
      },
      {
        "slug": "frmd4a",
        "symbol": "FRMD4A",
        "hgnc": "HGNC:25491",
        "name": "FERM domain containing 4A",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/frmd4a"
      },
      {
        "slug": "fut8",
        "symbol": "FUT8",
        "hgnc": "HGNC:4019",
        "name": "fucosyltransferase 8",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fut8"
      },
      {
        "slug": "gnas",
        "symbol": "GNAS",
        "hgnc": "HGNC:4392",
        "name": "GNAS complex locus",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnas"
      },
      {
        "slug": "gne",
        "symbol": "GNE",
        "hgnc": "HGNC:23657",
        "name": "glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gne"
      },
      {
        "slug": "h6pd",
        "symbol": "H6PD",
        "hgnc": "HGNC:4795",
        "name": "hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/h6pd"
      },
      {
        "slug": "hnrnpr",
        "symbol": "HNRNPR",
        "hgnc": "HGNC:5047",
        "name": "heterogeneous nuclear ribonucleoprotein R",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hnrnpr"
      },
      {
        "slug": "kcnh1",
        "symbol": "KCNH1",
        "hgnc": "HGNC:6250",
        "name": "potassium voltage-gated channel subfamily H member 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnh1"
      },
      {
        "slug": "kdm1a",
        "symbol": "KDM1A",
        "hgnc": "HGNC:29079",
        "name": "lysine demethylase 1A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdm1a"
      },
      {
        "slug": "kdm6a",
        "symbol": "KDM6A",
        "hgnc": "HGNC:12637",
        "name": "lysine demethylase 6A",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/kdm6a"
      },
      {
        "slug": "mogs",
        "symbol": "MOGS",
        "hgnc": "HGNC:24862",
        "name": "mannosyl-oligosaccharide glucosidase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mogs"
      },
      {
        "slug": "nipbl",
        "symbol": "NIPBL",
        "hgnc": "HGNC:28862",
        "name": "NIPBL cohesin loading factor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nipbl"
      },
      {
        "slug": "otud5",
        "symbol": "OTUD5",
        "hgnc": "HGNC:25402",
        "name": "OTU deubiquitinase 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/otud5"
      },
      {
        "slug": "pepd",
        "symbol": "PEPD",
        "hgnc": "HGNC:8840",
        "name": "peptidase D",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pepd"
      },
      {
        "slug": "plaa",
        "symbol": "PLAA",
        "hgnc": "HGNC:9043",
        "name": "phospholipase A2 activating protein",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/plaa"
      },
      {
        "slug": "polr3a",
        "symbol": "POLR3A",
        "hgnc": "HGNC:30074",
        "name": "RNA polymerase III subunit A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/polr3a"
      },
      {
        "slug": "por",
        "symbol": "POR",
        "hgnc": "HGNC:9208",
        "name": "cytochrome p450 oxidoreductase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/por"
      },
      {
        "slug": "recql",
        "symbol": "RECQL",
        "hgnc": "HGNC:9948",
        "name": "RecQ like helicase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/recql"
      },
      {
        "slug": "shroom4",
        "symbol": "SHROOM4",
        "hgnc": "HGNC:29215",
        "name": "shroom family member 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/shroom4"
      },
      {
        "slug": "smarca4",
        "symbol": "SMARCA4",
        "hgnc": "HGNC:11100",
        "name": "SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smarca4"
      },
      {
        "slug": "smarcb1",
        "symbol": "SMARCB1",
        "hgnc": "HGNC:11103",
        "name": "SWI/SNF related BAF chromatin remodeling complex subunit B1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/smarcb1"
      },
      {
        "slug": "smarcc2",
        "symbol": "SMARCC2",
        "hgnc": "HGNC:11105",
        "name": "SWI/SNF related BAF chromatin remodeling complex subunit C2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smarcc2"
      },
      {
        "slug": "smarcd1",
        "symbol": "SMARCD1",
        "hgnc": "HGNC:11106",
        "name": "SWI/SNF related BAF chromatin remodeling complex subunit D1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smarcd1"
      },
      {
        "slug": "smarcd2",
        "symbol": "SMARCD2",
        "hgnc": "HGNC:11107",
        "name": "SWI/SNF related BAF chromatin remodeling complex subunit D2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smarcd2"
      },
      {
        "slug": "smarce1",
        "symbol": "SMARCE1",
        "hgnc": "HGNC:11109",
        "name": "SWI/SNF related BAF chromatin remodeling complex subunit E1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smarce1"
      },
      {
        "slug": "sox11",
        "symbol": "SOX11",
        "hgnc": "HGNC:11191",
        "name": "SRY-box transcription factor 11",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox11"
      },
      {
        "slug": "sox4",
        "symbol": "SOX4",
        "hgnc": "HGNC:11200",
        "name": "SRY-box transcription factor 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox4"
      },
      {
        "slug": "tasp1",
        "symbol": "TASP1",
        "hgnc": "HGNC:15859",
        "name": "taspase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tasp1"
      },
      {
        "slug": "tp53",
        "symbol": "TP53",
        "hgnc": "HGNC:11998",
        "name": "tumor protein p53",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tp53"
      },
      {
        "slug": "usp48",
        "symbol": "USP48",
        "hgnc": "HGNC:18533",
        "name": "ubiquitin specific peptidase 48",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/usp48"
      },
      {
        "slug": "usp8",
        "symbol": "USP8",
        "hgnc": "HGNC:12631",
        "name": "ubiquitin specific peptidase 8",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/usp8"
      },
      {
        "slug": "vps33a",
        "symbol": "VPS33A",
        "hgnc": "HGNC:18179",
        "name": "VPS33A core subunit of CORVET and HOPS complexes",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vps33a"
      },
      {
        "slug": "adamtsl2",
        "symbol": "ADAMTSL2",
        "hgnc": "HGNC:14631",
        "name": "ADAMTS like 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adamtsl2"
      },
      {
        "slug": "alms1",
        "symbol": "ALMS1",
        "hgnc": "HGNC:428",
        "name": "ALMS1 centrosome and basal body associated protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alms1"
      },
      {
        "slug": "asxl3",
        "symbol": "ASXL3",
        "hgnc": "HGNC:29357",
        "name": "ASXL transcriptional regulator 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/asxl3"
      },
      {
        "slug": "cacna1g",
        "symbol": "CACNA1G",
        "hgnc": "HGNC:1394",
        "name": "calcium voltage-gated channel subunit alpha1 G",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacna1g"
      },
      {
        "slug": "capn15",
        "symbol": "CAPN15",
        "hgnc": "HGNC:11182",
        "name": "calpain 15",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/capn15"
      },
      {
        "slug": "cavin1",
        "symbol": "CAVIN1",
        "hgnc": "HGNC:9688",
        "name": "caveolae associated protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cavin1"
      },
      {
        "slug": "fbxo11",
        "symbol": "FBXO11",
        "hgnc": "HGNC:13590",
        "name": "F-box protein 11",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fbxo11"
      },
      {
        "slug": "glb1",
        "symbol": "GLB1",
        "hgnc": "HGNC:4298",
        "name": "galactosidase beta 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/glb1"
      },
      {
        "slug": "gli3",
        "symbol": "GLI3",
        "hgnc": "HGNC:4319",
        "name": "GLI family zinc finger 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gli3"
      },
      {
        "slug": "gnb2",
        "symbol": "GNB2",
        "hgnc": "HGNC:4398",
        "name": "G protein subunit beta 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnb2"
      },
      {
        "slug": "hgsnat",
        "symbol": "HGSNAT",
        "hgnc": "HGNC:26527",
        "name": "heparan-alpha-glucosaminide N-acetyltransferase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hgsnat"
      },
      {
        "slug": "hivep2",
        "symbol": "HIVEP2",
        "hgnc": "HGNC:4921",
        "name": "HIVEP zinc finger 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hivep2"
      },
      {
        "slug": "hsd3b2",
        "symbol": "HSD3B2",
        "hgnc": "HGNC:5218",
        "name": "hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hsd3b2"
      },
      {
        "slug": "hspg2",
        "symbol": "HSPG2",
        "hgnc": "HGNC:5273",
        "name": "heparan sulfate proteoglycan 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hspg2"
      },
      {
        "slug": "ipo8",
        "symbol": "IPO8",
        "hgnc": "HGNC:9853",
        "name": "importin 8",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ipo8"
      },
      {
        "slug": "lrpprc",
        "symbol": "LRPPRC",
        "hgnc": "HGNC:15714",
        "name": "leucine rich pentatricopeptide repeat containing",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrpprc"
      },
      {
        "slug": "map3k1",
        "symbol": "MAP3K1",
        "hgnc": "HGNC:6848",
        "name": "mitogen-activated protein kinase kinase kinase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/map3k1"
      },
      {
        "slug": "map3k7",
        "symbol": "MAP3K7",
        "hgnc": "HGNC:6859",
        "name": "mitogen-activated protein kinase kinase kinase 7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/map3k7"
      },
      {
        "slug": "mdga2",
        "symbol": "MDGA2",
        "hgnc": "HGNC:19835",
        "name": "MAM domain containing glycosylphosphatidylinositol anchor 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mdga2"
      },
      {
        "slug": "mgat2",
        "symbol": "MGAT2",
        "hgnc": "HGNC:7045",
        "name": "alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/mgat2"
      },
      {
        "slug": "nkx6-2",
        "symbol": "NKX6-2",
        "hgnc": "HGNC:19321",
        "name": "NK6 homeobox 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nkx6-2"
      },
      {
        "slug": "pde11a",
        "symbol": "PDE11A",
        "hgnc": "HGNC:8773",
        "name": "phosphodiesterase 11A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pde11a"
      },
      {
        "slug": "prkar1a",
        "symbol": "PRKAR1A",
        "hgnc": "HGNC:9388",
        "name": "protein kinase cAMP-dependent type I regulatory subunit alpha",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/prkar1a"
      },
      {
        "slug": "rpl10",
        "symbol": "RPL10",
        "hgnc": "HGNC:10298",
        "name": "ribosomal protein L10",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rpl10"
      },
      {
        "slug": "setbp1",
        "symbol": "SETBP1",
        "hgnc": "HGNC:15573",
        "name": "SET binding protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/setbp1"
      },
      {
        "slug": "smc1a",
        "symbol": "SMC1A",
        "hgnc": "HGNC:11111",
        "name": "structural maintenance of chromosomes 1A",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/smc1a"
      },
      {
        "slug": "smo",
        "symbol": "SMO",
        "hgnc": "HGNC:11119",
        "name": "smoothened, frizzled class receptor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smo"
      },
      {
        "slug": "sox6",
        "symbol": "SOX6",
        "hgnc": "HGNC:16421",
        "name": "SRY-box transcription factor 6",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox6"
      },
      {
        "slug": "spen",
        "symbol": "SPEN",
        "hgnc": "HGNC:17575",
        "name": "spen family transcriptional repressor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spen"
      },
      {
        "slug": "taf1",
        "symbol": "TAF1",
        "hgnc": "HGNC:11535",
        "name": "TATA-box binding protein associated factor 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/taf1"
      },
      {
        "slug": "tbc1d20",
        "symbol": "TBC1D20",
        "hgnc": "HGNC:16133",
        "name": "TBC1 domain family member 20",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbc1d20"
      },
      {
        "slug": "tbck",
        "symbol": "TBCK",
        "hgnc": "HGNC:28261",
        "name": "TBC1 domain containing kinase",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tbck"
      },
      {
        "slug": "toe1",
        "symbol": "TOE1",
        "hgnc": "HGNC:15954",
        "name": "target of EGR1, exonuclease",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/toe1"
      },
      {
        "slug": "trio",
        "symbol": "TRIO",
        "hgnc": "HGNC:12303",
        "name": "trio Rho guanine nucleotide exchange factor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trio"
      },
      {
        "slug": "ttc5",
        "symbol": "TTC5",
        "hgnc": "HGNC:19274",
        "name": "tetratricopeptide repeat domain 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ttc5"
      },
      {
        "slug": "ufc1",
        "symbol": "UFC1",
        "hgnc": "HGNC:26941",
        "name": "ubiquitin-fold modifier conjugating enzyme 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ufc1"
      },
      {
        "slug": "wac",
        "symbol": "WAC",
        "hgnc": "HGNC:17327",
        "name": "WW domain containing adaptor with coiled-coil",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/wac"
      },
      {
        "slug": "wdr26",
        "symbol": "WDR26",
        "hgnc": "HGNC:21208",
        "name": "WD repeat domain 26",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wdr26"
      },
      {
        "slug": "wdr83os",
        "symbol": "WDR83OS",
        "hgnc": "HGNC:30203",
        "name": "WD repeat domain 83 opposite strand",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wdr83os"
      },
      {
        "slug": "xylt1",
        "symbol": "XYLT1",
        "hgnc": "HGNC:15516",
        "name": "xylosyltransferase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/xylt1"
      },
      {
        "slug": "adnp",
        "symbol": "ADNP",
        "hgnc": "HGNC:15766",
        "name": "activity dependent neuroprotector homeobox",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adnp"
      },
      {
        "slug": "tbcd",
        "symbol": "TBCD",
        "hgnc": "HGNC:11581",
        "name": "tubulin folding cofactor D",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbcd"
      },
      {
        "slug": "agpat2",
        "symbol": "AGPAT2",
        "hgnc": "HGNC:325",
        "name": "1-acylglycerol-3-phosphate O-acyltransferase 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/agpat2"
      },
      {
        "slug": "aip",
        "symbol": "AIP",
        "hgnc": "HGNC:358",
        "name": "AHR interacting HSP90 co-chaperone",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aip"
      },
      {
        "slug": "arl6",
        "symbol": "ARL6",
        "hgnc": "HGNC:13210",
        "name": "ARF like GTPase 6",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arl6"
      },
      {
        "slug": "arx",
        "symbol": "ARX",
        "hgnc": "HGNC:18060",
        "name": "aristaless related homeobox",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arx"
      },
      {
        "slug": "asxl1",
        "symbol": "ASXL1",
        "hgnc": "HGNC:18318",
        "name": "ASXL transcriptional regulator 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/asxl1"
      },
      {
        "slug": "bbs1",
        "symbol": "BBS1",
        "hgnc": "HGNC:966",
        "name": "Bardet-Biedl syndrome 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbs1"
      },
      {
        "slug": "bcl11b",
        "symbol": "BCL11B",
        "hgnc": "HGNC:13222",
        "name": "BCL11 transcription factor B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bcl11b"
      },
      {
        "slug": "bscl2",
        "symbol": "BSCL2",
        "hgnc": "HGNC:15832",
        "name": "BSCL2 lipid droplet biogenesis associated, seipin",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bscl2"
      },
      {
        "slug": "cav1",
        "symbol": "CAV1",
        "hgnc": "HGNC:1527",
        "name": "caveolin 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cav1"
      },
      {
        "slug": "ccbe1",
        "symbol": "CCBE1",
        "hgnc": "HGNC:29426",
        "name": "collagen and calcium binding EGF domains 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccbe1"
      },
      {
        "slug": "ccdc28b",
        "symbol": "CCDC28B",
        "hgnc": "HGNC:28163",
        "name": "coiled-coil domain containing 28B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc28b"
      },
      {
        "slug": "ercc6",
        "symbol": "ERCC6",
        "hgnc": "HGNC:3438",
        "name": "ERCC excision repair 6, chromatin remodeling factor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ercc6"
      },
      {
        "slug": "flna",
        "symbol": "FLNA",
        "hgnc": "HGNC:3754",
        "name": "filamin A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flna"
      },
      {
        "slug": "gns",
        "symbol": "GNS",
        "hgnc": "HGNC:4422",
        "name": "glucosamine (N-acetyl)-6-sulfatase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gns"
      },
      {
        "slug": "gusb",
        "symbol": "GUSB",
        "hgnc": "HGNC:4696",
        "name": "glucuronidase beta",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gusb"
      },
      {
        "slug": "idua",
        "symbol": "IDUA",
        "hgnc": "HGNC:5391",
        "name": "alpha-L-iduronidase",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/idua"
      },
      {
        "slug": "kmt2d",
        "symbol": "KMT2D",
        "hgnc": "HGNC:7133",
        "name": "lysine methyltransferase 2D",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kmt2d"
      },
      {
        "slug": "lmna",
        "symbol": "LMNA",
        "hgnc": "HGNC:6636",
        "name": "lamin A/C",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmna"
      },
      {
        "slug": "lmnb2",
        "symbol": "LMNB2",
        "hgnc": "HGNC:6638",
        "name": "lamin B2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmnb2"
      },
      {
        "slug": "naglu",
        "symbol": "NAGLU",
        "hgnc": "HGNC:7632",
        "name": "N-acetyl-alpha-glucosaminidase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/naglu"
      },
      {
        "slug": "nans",
        "symbol": "NANS",
        "hgnc": "HGNC:19237",
        "name": "N-acetylneuraminate synthase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nans"
      },
      {
        "slug": "notch2",
        "symbol": "NOTCH2",
        "hgnc": "HGNC:7882",
        "name": "notch receptor 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/notch2"
      },
      {
        "slug": "papss2",
        "symbol": "PAPSS2",
        "hgnc": "HGNC:8604",
        "name": "3'-phosphoadenosine 5'-phosphosulfate synthase 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/papss2"
      },
      {
        "slug": "pparg",
        "symbol": "PPARG",
        "hgnc": "HGNC:9236",
        "name": "peroxisome proliferator activated receptor gamma",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pparg"
      },
      {
        "slug": "prkaca",
        "symbol": "PRKACA",
        "hgnc": "HGNC:9380",
        "name": "protein kinase cAMP-activated catalytic subunit alpha",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prkaca"
      },
      {
        "slug": "setd2",
        "symbol": "SETD2",
        "hgnc": "HGNC:18420",
        "name": "SET domain containing 2, histone lysine methyltransferase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/setd2"
      },
      {
        "slug": "sgsh",
        "symbol": "SGSH",
        "hgnc": "HGNC:10818",
        "name": "N-sulfoglucosamine sulfohydrolase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sgsh"
      },
      {
        "slug": "srcap",
        "symbol": "SRCAP",
        "hgnc": "HGNC:16974",
        "name": "Snf2 related CREBBP activator protein",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/srcap"
      },
      {
        "slug": "wdr81",
        "symbol": "WDR81",
        "hgnc": "HGNC:26600",
        "name": "WD repeat domain 81",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wdr81"
      }
    ]
  }
}