{
  "url": "https://dantelabs.com/traits/cleft-helix",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "cleft-helix",
    "id": "HP:0009902",
    "name": "Cleft helix",
    "definition": "A notched form of the helix of the ear. That is, a defect in the continuity of the helix, which may occur at any point along its length.",
    "synonyms": [
      "Notched helix",
      "Notching of the ear helix"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-ear",
        "name": "Abnormality of the ear",
        "url": "https://dantelabs.com/traits/abnormality-of-the-ear"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-helix-morphology",
        "name": "Abnormal helix morphology",
        "url": "https://dantelabs.com/traits/abnormal-helix-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "cleft-at-the-superior-portion-of-the-pinna",
        "name": "Cleft at the superior portion of the pinna",
        "genes": 2,
        "url": "https://dantelabs.com/traits/cleft-at-the-superior-portion-of-the-pinna"
      }
    ],
    "genes": [
      {
        "slug": "edn1",
        "symbol": "EDN1",
        "hgnc": "HGNC:3176",
        "name": "endothelin 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/edn1"
      },
      {
        "slug": "gnai3",
        "symbol": "GNAI3",
        "hgnc": "HGNC:4387",
        "name": "G protein subunit alpha i3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnai3"
      },
      {
        "slug": "plcb4",
        "symbol": "PLCB4",
        "hgnc": "HGNC:9059",
        "name": "phospholipase C beta 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/plcb4"
      }
    ]
  }
}