{
  "url": "https://dantelabs.com/traits/bladder-neoplasm",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "bladder-neoplasm",
    "id": "HP:0009725",
    "name": "Bladder neoplasm",
    "definition": "The presence of a neoplasm of the urinary bladder.",
    "synonyms": [
      "Bladder cancer"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      },
      {
        "slug": "neoplasm",
        "name": "Abnormal tissue mass",
        "url": "https://dantelabs.com/traits/neoplasm"
      }
    ],
    "broader": [
      {
        "slug": "urinary-tract-neoplasm",
        "name": "Urinary tract neoplasm",
        "url": "https://dantelabs.com/traits/urinary-tract-neoplasm"
      }
    ],
    "narrower": [
      {
        "slug": "bladder-carcinoma",
        "name": "Bladder carcinoma",
        "genes": 3,
        "url": "https://dantelabs.com/traits/bladder-carcinoma"
      }
    ],
    "genes": [
      {
        "slug": "nthl1",
        "symbol": "NTHL1",
        "hgnc": "HGNC:8028",
        "name": "nth like DNA glycosylase 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/nthl1"
      },
      {
        "slug": "fgfr3",
        "symbol": "FGFR3",
        "hgnc": "HGNC:3690",
        "name": "fibroblast growth factor receptor 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgfr3"
      },
      {
        "slug": "hras",
        "symbol": "HRAS",
        "hgnc": "HGNC:5173",
        "name": "HRas proto-oncogene, GTPase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hras"
      },
      {
        "slug": "kras",
        "symbol": "KRAS",
        "hgnc": "HGNC:6407",
        "name": "KRas proto-oncogene, GTPase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kras"
      },
      {
        "slug": "rb1",
        "symbol": "RB1",
        "hgnc": "HGNC:9884",
        "name": "RB transcriptional corepressor 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rb1"
      }
    ]
  }
}