{
  "url": "https://dantelabs.com/traits/autoamputation",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "autoamputation",
    "id": "HP:0001218",
    "name": "Autoamputation",
    "definition": "Auto-amputation is the spontaneous detachment of an appendage from the body due to long standing pathology.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-limbs",
        "name": "Abnormality of limbs",
        "url": "https://dantelabs.com/traits/abnormality-of-limbs"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-limbs",
        "name": "Abnormality of limbs",
        "url": "https://dantelabs.com/traits/abnormality-of-limbs"
      }
    ],
    "narrower": [
      {
        "slug": "autoamputation-of-digits",
        "name": "Autoamputation of digits",
        "genes": 14,
        "url": "https://dantelabs.com/traits/autoamputation-of-digits"
      },
      {
        "slug": "autoamputation-of-foot",
        "name": "Autoamputation of foot",
        "genes": 2,
        "url": "https://dantelabs.com/traits/autoamputation-of-foot"
      }
    ],
    "genes": [
      {
        "slug": "slurp1",
        "symbol": "SLURP1",
        "hgnc": "HGNC:18746",
        "name": "secreted LY6/PLAUR domain containing 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slurp1"
      },
      {
        "slug": "rab7a",
        "symbol": "RAB7A",
        "hgnc": "HGNC:9788",
        "name": "RAB7A, member RAS oncogene family",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab7a"
      }
    ]
  }
}