{
  "url": "https://dantelabs.com/pt/genes/taf11",
  "gene": {
    "slug": "taf11",
    "symbol": "TAF11",
    "name": "TATA-box binding protein associated factor 11",
    "hgnc": "HGNC:11544",
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    "location": "6p21.31",
    "locusType": "gene with protein product",
    "aliases": [
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    "previousSymbols": [
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    "omim": [
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    "uniprot": [
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      "release": "v1.5",
      "chrom": "6",
      "start": 34877462,
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      "strand": "-",
      "ensemblTranscript": "ENST00000361288.9",
      "refseqTranscript": "NM_005643.4",
      "ensemblProtein": "ENSP00000354633.4",
      "refseqProtein": "NP_005634.1",
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        {
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        {
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          "biotype": "protein_coding",
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        {
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        {
          "symbol": "SNRPC",
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          "slug": "snrpc"
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        {
          "symbol": "BLTP3A",
          "ensemblId": "ENSG00000065060",
          "biotype": "protein_coding",
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          "strand": "+",
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        },
        {
          "symbol": "ANKS1A",
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          "biotype": "protein_coding",
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          "strand": "+",
          "slug": "anks1a"
        },
        {
          "symbol": "TCP11",
          "ensemblId": "ENSG00000124678",
          "biotype": "protein_coding",
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          "strand": "-",
          "slug": "tcp11"
        },
        {
          "symbol": "SCUBE3",
          "ensemblId": "ENSG00000146197",
          "biotype": "protein_coding",
          "start": 35213859,
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        {
          "symbol": "ZNF76",
          "ensemblId": "ENSG00000065029",
          "biotype": "protein_coding",
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          "slug": "znf76"
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        {
          "symbol": "DEF6",
          "ensemblId": "ENSG00000023892",
          "biotype": "protein_coding",
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          "slug": "def6"
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        {
          "symbol": "PPARD",
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          "strand": "+",
          "slug": "ppard"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormal-eustachian-tube-morphology",
        "name": "Abnormal Eustachian tube morphology",
        "systems": [
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        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-eustachian-tube-morphology"
      },
      {
        "slug": "situs-inversus-totalis",
        "name": "All organs on wrong side of body",
        "systems": [
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        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/situs-inversus-totalis"
      },
      {
        "slug": "atypical-behavior",
        "name": "Behavioral abnormality",
        "systems": [
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        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/atypical-behavior"
      },
      {
        "slug": "bilateral-cleft-lip",
        "name": "Both sided cleft lip",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/bilateral-cleft-lip"
      },
      {
        "slug": "chronic-otitis-media",
        "name": "Chronic infections of the middle ear",
        "systems": [
          "abnormality-of-the-ear",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/chronic-otitis-media"
      },
      {
        "slug": "talipes-equinovarus",
        "name": "Club feet",
        "systems": [
          "abnormality-of-limbs"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/talipes-equinovarus"
      },
      {
        "slug": "conductive-hearing-impairment",
        "name": "Conductive deafness",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/conductive-hearing-impairment"
      },
      {
        "slug": "supernumerary-maxillary-incisor",
        "name": "Extra upper front tooth",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/supernumerary-maxillary-incisor"
      },
      {
        "slug": "hypodontia",
        "name": "Failure of development of between one and six teeth",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/hypodontia"
      },
      {
        "slug": "polyhydramnios",
        "name": "High levels of amniotic fluid",
        "systems": [
          "abnormality-of-prenatal-development-or-birth"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/polyhydramnios"
      },
      {
        "slug": "macrodontia",
        "name": "Increased size of tooth",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/macrodontia"
      },
      {
        "slug": "low-self-esteem",
        "name": "Low self-esteem",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/low-self-esteem"
      },
      {
        "slug": "non-midline-cleft-of-the-upper-lip",
        "name": "Non-midline cleft of the upper lip",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/non-midline-cleft-of-the-upper-lip"
      },
      {
        "slug": "small-for-gestational-age",
        "name": "Small for gestational age",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/small-for-gestational-age"
      },
      {
        "slug": "specific-learning-disability",
        "name": "Specific learning disability",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/specific-learning-disability"
      },
      {
        "slug": "speech-articulation-difficulties",
        "name": "Speech articulation difficulties",
        "systems": [
          "abnormality-of-the-nervous-system",
          "abnormality-of-the-voice"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/speech-articulation-difficulties"
      },
      {
        "slug": "umbilical-hernia",
        "name": "Umbilical hernia",
        "systems": [
          "abnormality-of-the-digestive-system",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/umbilical-hernia"
      },
      {
        "slug": "velopharyngeal-insufficiency",
        "name": "Velopharyngeal incompetence",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/velopharyngeal-insufficiency"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}