{
  "url": "https://dantelabs.com/pt/genes/rpl18",
  "gene": {
    "slug": "rpl18",
    "symbol": "RPL18",
    "name": "ribosomal protein L18",
    "hgnc": "HGNC:10310",
    "summary": null,
    "location": "19q13.33",
    "locusType": "gene with protein product",
    "aliases": [
      "L18",
      "eL18"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000063177",
    "entrezId": 6141,
    "omim": [
      "604179"
    ],
    "uniprot": [
      "Q07020"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "19",
      "start": 48615331,
      "end": 48619178,
      "strand": "-",
      "ensemblTranscript": "ENST00000549920.6",
      "refseqTranscript": "NM_000979.4",
      "ensemblProtein": "ENSP00000447001.1",
      "refseqProtein": "NP_000970.1",
      "exons": [
        {
          "start": 48615331,
          "end": 48615447
        },
        {
          "start": 48615877,
          "end": 48615946
        },
        {
          "start": 48616079,
          "end": 48616202
        },
        {
          "start": 48616726,
          "end": 48616824
        },
        {
          "start": 48617316,
          "end": 48617423
        },
        {
          "start": 48617791,
          "end": 48617877
        },
        {
          "start": 48619141,
          "end": 48619178
        }
      ],
      "cds": {
        "start": 48615372,
        "end": 48619143
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "19",
      "start": 49118585,
      "end": 49122793,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 48117255,
      "end": 49117254,
      "genes": [
        {
          "symbol": "LIG1",
          "ensemblId": "ENSG00000105486",
          "biotype": "protein_coding",
          "start": 48115444,
          "end": 48170654,
          "strand": "-",
          "slug": "lig1"
        },
        {
          "symbol": "ZSWIM9",
          "ensemblId": "ENSG00000185453",
          "biotype": "protein_coding",
          "start": 48170645,
          "end": 48197624,
          "strand": "+",
          "slug": "zswim9"
        },
        {
          "symbol": "CARD8",
          "ensemblId": "ENSG00000105483",
          "biotype": "protein_coding",
          "start": 48180770,
          "end": 48255976,
          "strand": "-",
          "slug": "card8"
        },
        {
          "symbol": "ZNF114",
          "ensemblId": "ENSG00000178150",
          "biotype": "protein_coding",
          "start": 48270041,
          "end": 48289292,
          "strand": "+",
          "slug": "znf114"
        },
        {
          "symbol": "ODAD1",
          "ensemblId": "ENSG00000105479",
          "biotype": "protein_coding",
          "start": 48296355,
          "end": 48321971,
          "strand": "-",
          "slug": "odad1"
        },
        {
          "symbol": "EMP3",
          "ensemblId": "ENSG00000142227",
          "biotype": "protein_coding",
          "start": 48321310,
          "end": 48330560,
          "strand": "+",
          "slug": "emp3"
        },
        {
          "symbol": "TMEM143",
          "ensemblId": "ENSG00000161558",
          "biotype": "protein_coding",
          "start": 48329918,
          "end": 48364245,
          "strand": "-",
          "slug": "tmem143"
        },
        {
          "symbol": "SYNGR4",
          "ensemblId": "ENSG00000105467",
          "biotype": "protein_coding",
          "start": 48364260,
          "end": 48376377,
          "strand": "+",
          "slug": "syngr4"
        },
        {
          "symbol": "KDELR1",
          "ensemblId": "ENSG00000105438",
          "biotype": "protein_coding",
          "start": 48382558,
          "end": 48393837,
          "strand": "-",
          "slug": "kdelr1"
        },
        {
          "symbol": "GRIN2D",
          "ensemblId": "ENSG00000105464",
          "biotype": "protein_coding",
          "start": 48393668,
          "end": 48444931,
          "strand": "+",
          "slug": "grin2d"
        },
        {
          "symbol": "GRWD1",
          "ensemblId": "ENSG00000105447",
          "biotype": "protein_coding",
          "start": 48445512,
          "end": 48458382,
          "strand": "+",
          "slug": "grwd1"
        },
        {
          "symbol": "KCNJ14",
          "ensemblId": "ENSG00000182324",
          "biotype": "protein_coding",
          "start": 48454464,
          "end": 48466980,
          "strand": "+",
          "slug": "kcnj14"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000268465",
          "biotype": "protein_coding",
          "start": 48465837,
          "end": 48472431,
          "strand": "+"
        },
        {
          "symbol": "CYTH2",
          "ensemblId": "ENSG00000105443",
          "biotype": "protein_coding",
          "start": 48469203,
          "end": 48482314,
          "strand": "+",
          "slug": "cyth2"
        },
        {
          "symbol": "LMTK3",
          "ensemblId": "ENSG00000142235",
          "biotype": "protein_coding",
          "start": 48485271,
          "end": 48513935,
          "strand": "-",
          "slug": "lmtk3"
        },
        {
          "symbol": "SULT2B1",
          "ensemblId": "ENSG00000088002",
          "biotype": "protein_coding",
          "start": 48552140,
          "end": 48599425,
          "strand": "+",
          "slug": "sult2b1"
        },
        {
          "symbol": "SACK1E",
          "ensemblId": "ENSG00000105523",
          "biotype": "protein_coding",
          "start": 48599961,
          "end": 48615093,
          "strand": "-",
          "slug": "sack1e"
        },
        {
          "symbol": "SPACA4",
          "ensemblId": "ENSG00000177202",
          "biotype": "protein_coding",
          "start": 48606742,
          "end": 48607962,
          "strand": "+",
          "slug": "spaca4"
        },
        {
          "symbol": "SPHK2",
          "ensemblId": "ENSG00000063176",
          "biotype": "protein_coding",
          "start": 48619291,
          "end": 48630717,
          "strand": "+",
          "slug": "sphk2"
        },
        {
          "symbol": "DBP",
          "ensemblId": "ENSG00000105516",
          "biotype": "protein_coding",
          "start": 48630030,
          "end": 48637695,
          "strand": "-",
          "slug": "dbp"
        },
        {
          "symbol": "CA11",
          "ensemblId": "ENSG00000063180",
          "biotype": "protein_coding",
          "start": 48637946,
          "end": 48646386,
          "strand": "-",
          "slug": "ca11"
        },
        {
          "symbol": "NTN5",
          "ensemblId": "ENSG00000142233",
          "biotype": "protein_coding",
          "start": 48661407,
          "end": 48673081,
          "strand": "-",
          "slug": "ntn5"
        },
        {
          "symbol": "FUT2",
          "ensemblId": "ENSG00000176920",
          "biotype": "protein_coding",
          "start": 48695953,
          "end": 48705951,
          "strand": "+",
          "slug": "fut2"
        },
        {
          "symbol": "MAMSTR",
          "ensemblId": "ENSG00000176909",
          "biotype": "protein_coding",
          "start": 48711737,
          "end": 48719966,
          "strand": "-",
          "slug": "mamstr"
        },
        {
          "symbol": "RASIP1",
          "ensemblId": "ENSG00000105538",
          "biotype": "protein_coding",
          "start": 48720571,
          "end": 48740616,
          "strand": "-",
          "slug": "rasip1"
        },
        {
          "symbol": "IZUMO1",
          "ensemblId": "ENSG00000182264",
          "biotype": "protein_coding",
          "start": 48740852,
          "end": 48746909,
          "strand": "-",
          "slug": "izumo1"
        },
        {
          "symbol": "FUT1",
          "ensemblId": "ENSG00000174951",
          "biotype": "protein_coding",
          "start": 48748011,
          "end": 48755390,
          "strand": "-",
          "slug": "fut1"
        },
        {
          "symbol": "FGF21",
          "ensemblId": "ENSG00000105550",
          "biotype": "protein_coding",
          "start": 48755524,
          "end": 48758333,
          "strand": "+",
          "slug": "fgf21"
        },
        {
          "symbol": "BCAT2",
          "ensemblId": "ENSG00000105552",
          "biotype": "protein_coding",
          "start": 48795061,
          "end": 48811066,
          "strand": "-",
          "slug": "bcat2"
        },
        {
          "symbol": "HSD17B14",
          "ensemblId": "ENSG00000087076",
          "biotype": "protein_coding",
          "start": 48813014,
          "end": 48837064,
          "strand": "-",
          "slug": "hsd17b14"
        },
        {
          "symbol": "PLEKHA4",
          "ensemblId": "ENSG00000105559",
          "biotype": "protein_coding",
          "start": 48837091,
          "end": 48868855,
          "strand": "-",
          "slug": "plekha4"
        },
        {
          "symbol": "PPP1R15A",
          "ensemblId": "ENSG00000087074",
          "biotype": "protein_coding",
          "start": 48872212,
          "end": 48879061,
          "strand": "+",
          "slug": "ppp1r15a"
        },
        {
          "symbol": "TULP2",
          "ensemblId": "ENSG00000104804",
          "biotype": "protein_coding",
          "start": 48880965,
          "end": 48898744,
          "strand": "-",
          "slug": "tulp2"
        },
        {
          "symbol": "NUCB1",
          "ensemblId": "ENSG00000104805",
          "biotype": "protein_coding",
          "start": 48900050,
          "end": 48923958,
          "strand": "+",
          "slug": "nucb1"
        },
        {
          "symbol": "DHDH",
          "ensemblId": "ENSG00000104808",
          "biotype": "protein_coding",
          "start": 48933517,
          "end": 48944969,
          "strand": "+",
          "slug": "dhdh"
        },
        {
          "symbol": "BAX",
          "ensemblId": "ENSG00000087088",
          "biotype": "protein_coding",
          "start": 48954815,
          "end": 48961806,
          "strand": "+",
          "slug": "bax"
        },
        {
          "symbol": "FTL",
          "ensemblId": "ENSG00000087086",
          "biotype": "protein_coding",
          "start": 48965275,
          "end": 48967896,
          "strand": "+",
          "slug": "ftl"
        },
        {
          "symbol": "GYS1",
          "ensemblId": "ENSG00000104812",
          "biotype": "protein_coding",
          "start": 48968125,
          "end": 48993349,
          "strand": "-",
          "slug": "gys1"
        },
        {
          "symbol": "RUVBL2",
          "ensemblId": "ENSG00000183207",
          "biotype": "protein_coding",
          "start": 48993476,
          "end": 49017868,
          "strand": "+",
          "slug": "ruvbl2"
        },
        {
          "symbol": "LHB",
          "ensemblId": "ENSG00000104826",
          "biotype": "protein_coding",
          "start": 49015980,
          "end": 49017091,
          "strand": "-",
          "slug": "lhb"
        },
        {
          "symbol": "SAXO3",
          "ensemblId": "ENSG00000268655",
          "biotype": "protein_coding",
          "start": 49017968,
          "end": 49020549,
          "strand": "-",
          "slug": "saxo3"
        },
        {
          "symbol": "CGB3",
          "ensemblId": "ENSG00000104827",
          "biotype": "protein_coding",
          "start": 49022869,
          "end": 49024360,
          "strand": "-",
          "slug": "cgb3"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000267335",
          "biotype": "protein_coding",
          "start": 49022953,
          "end": 49036895,
          "strand": "-"
        },
        {
          "symbol": "CGB2",
          "ensemblId": "ENSG00000104818",
          "biotype": "protein_coding",
          "start": 49031890,
          "end": 49033238,
          "strand": "+",
          "slug": "cgb2"
        },
        {
          "symbol": "CGB1",
          "ensemblId": "ENSG00000267631",
          "biotype": "protein_coding",
          "start": 49035569,
          "end": 49036895,
          "strand": "-",
          "slug": "cgb1"
        },
        {
          "symbol": "CGB5",
          "ensemblId": "ENSG00000189052",
          "biotype": "protein_coding",
          "start": 49043595,
          "end": 49045312,
          "strand": "+",
          "slug": "cgb5"
        },
        {
          "symbol": "CGB8",
          "ensemblId": "ENSG00000213030",
          "biotype": "protein_coding",
          "start": 49047638,
          "end": 49049125,
          "strand": "-",
          "slug": "cgb8"
        },
        {
          "symbol": "CGB7",
          "ensemblId": "ENSG00000196337",
          "biotype": "protein_coding",
          "start": 49054274,
          "end": 49058860,
          "strand": "-",
          "slug": "cgb7"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000283663",
          "biotype": "protein_coding",
          "start": 49055793,
          "end": 49065076,
          "strand": "-"
        },
        {
          "symbol": "NTF4",
          "ensemblId": "ENSG00000225950",
          "biotype": "protein_coding",
          "start": 49061066,
          "end": 49065076,
          "strand": "-",
          "slug": "ntf4"
        },
        {
          "symbol": "KCNA7",
          "ensemblId": "ENSG00000104848",
          "biotype": "protein_coding",
          "start": 49067397,
          "end": 49072702,
          "strand": "-",
          "slug": "kcna7"
        },
        {
          "symbol": "SNRNP70",
          "ensemblId": "ENSG00000104852",
          "biotype": "protein_coding",
          "start": 49085164,
          "end": 49108618,
          "strand": "+",
          "slug": "snrnp70"
        },
        {
          "symbol": "LIN7B",
          "ensemblId": "ENSG00000104863",
          "biotype": "protein_coding",
          "start": 49114324,
          "end": 49118463,
          "strand": "+",
          "slug": "lin7b"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "systems": [],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      },
      {
        "slug": "abnormality-of-the-head",
        "name": "Abnormality of the head",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormality-of-the-head"
      },
      {
        "slug": "abnormal-heart-morphology",
        "name": "Abnormality of the heart",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-heart-morphology"
      },
      {
        "slug": "abnormality-of-the-thenar-eminence",
        "name": "Abnormality of the thenar eminence",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormality-of-the-thenar-eminence"
      },
      {
        "slug": "abnormality-of-the-upper-limb",
        "name": "Abnormality of the upper limb",
        "systems": [
          "abnormality-of-limbs"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormality-of-the-upper-limb"
      },
      {
        "slug": "microcephaly",
        "name": "Abnormally small head",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/microcephaly"
      },
      {
        "slug": "renal-agenesis",
        "name": "Absent kidney",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/renal-agenesis"
      },
      {
        "slug": "absent-thumb",
        "name": "Absent thumb",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/absent-thumb"
      },
      {
        "slug": "acute-myeloid-leukemia",
        "name": "Acute myeloid leukemia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-the-immune-system",
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/acute-myeloid-leukemia"
      },
      {
        "slug": "adenocarcinoma-of-the-colon",
        "name": "Adenocarcinoma of the colon",
        "systems": [
          "abnormality-of-the-digestive-system",
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/adenocarcinoma-of-the-colon"
      },
      {
        "slug": "atrial-septal-defect",
        "name": "An opening in the wall separating the top two chambers of the heart",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/atrial-septal-defect"
      },
      {
        "slug": "osteosarcoma",
        "name": "Bone cell cancer",
        "systems": [
          "abnormality-of-the-musculoskeletal-system",
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/osteosarcoma"
      },
      {
        "slug": "cleft-lip",
        "name": "Cleft lip",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/cleft-lip"
      },
      {
        "slug": "cleft-soft-palate",
        "name": "Cleft soft palate",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/cleft-soft-palate"
      },
      {
        "slug": "developmental-cataract",
        "name": "Clouding of the lens of the eye at birth",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/developmental-cataract"
      },
      {
        "slug": "strabismus",
        "name": "Cross-eyed",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/strabismus"
      },
      {
        "slug": "decreased-total-leukocyte-count",
        "name": "Decreased blood leukocyte number",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/decreased-total-leukocyte-count"
      },
      {
        "slug": "depressed-nasal-bridge",
        "name": "Depressed nasal bridge",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/depressed-nasal-bridge"
      },
      {
        "slug": "developmental-glaucoma",
        "name": "Developmental glaucoma",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/developmental-glaucoma"
      },
      {
        "slug": "ptosis",
        "name": "Drooping upper eyelid",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/ptosis"
      },
      {
        "slug": "elevated-red-cell-adenosine-deaminase-activity",
        "name": "Elevated red cell adenosine deaminase activity",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/elevated-red-cell-adenosine-deaminase-activity"
      },
      {
        "slug": "erythroid-hypoplasia",
        "name": "Erythroid hypoplasia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/erythroid-hypoplasia"
      },
      {
        "slug": "epicanthus",
        "name": "Eye folds",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/epicanthus"
      },
      {
        "slug": "triphalangeal-thumb",
        "name": "Finger-like thumb",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/triphalangeal-thumb"
      },
      {
        "slug": "granulocytic-hypoplasia",
        "name": "Granulocytic hypoplasia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/granulocytic-hypoplasia"
      },
      {
        "slug": "growth-delay",
        "name": "Growth delay",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/growth-delay"
      },
      {
        "slug": "high-palate",
        "name": "High palate",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/high-palate"
      },
      {
        "slug": "sprengel-anomaly",
        "name": "High shoulder blade",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/sprengel-anomaly"
      },
      {
        "slug": "ventricular-septal-defect",
        "name": "Hole in heart wall separating two lower heart chambers",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/ventricular-septal-defect"
      },
      {
        "slug": "horseshoe-kidney",
        "name": "Horseshoe kidney",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/horseshoe-kidney"
      },
      {
        "slug": "hypospadias",
        "name": "Hypospadias",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/hypospadias"
      },
      {
        "slug": "increased-mean-corpuscular-volume",
        "name": "Increased mean corpuscular volume",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/increased-mean-corpuscular-volume"
      },
      {
        "slug": "thrombocytosis",
        "name": "Increased number of platelets in blood",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/thrombocytosis"
      },
      {
        "slug": "lethargy",
        "name": "Lethargy",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/lethargy"
      },
      {
        "slug": "micrognathia",
        "name": "Little lower jaw",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/micrognathia"
      },
      {
        "slug": "decreased-total-neutrophil-count",
        "name": "Low blood neutrophil count",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/decreased-total-neutrophil-count"
      },
      {
        "slug": "low-anterior-hairline",
        "name": "Low frontal hairline",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-integument"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/low-anterior-hairline"
      },
      {
        "slug": "thrombocytopenia",
        "name": "Low platelet count",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/thrombocytopenia"
      },
      {
        "slug": "low-set-ears",
        "name": "Low-set ears",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/low-set-ears"
      },
      {
        "slug": "macrocytic-dyserythropoietic-anemia",
        "name": "Macrocytic dyserythropoietic anemia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/macrocytic-dyserythropoietic-anemia"
      },
      {
        "slug": "malignant-genitourinary-tract-tumor",
        "name": "Malignant genitourinary tract tumor",
        "systems": [
          "abnormality-of-the-genitourinary-system",
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/malignant-genitourinary-tract-tumor"
      },
      {
        "slug": "myelodysplasia",
        "name": "Myelodysplasia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "neoplasm"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/myelodysplasia"
      },
      {
        "slug": "coarctation-of-aorta",
        "name": "Narrowing of aorta",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/coarctation-of-aorta"
      },
      {
        "slug": "neurodevelopmental-delay",
        "name": "Neurodevelopmental delay",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/neurodevelopmental-delay"
      },
      {
        "slug": "nonimmune-hydrops-fetalis",
        "name": "Nonimmune hydrops fetalis",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-prenatal-development-or-birth"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/nonimmune-hydrops-fetalis"
      },
      {
        "slug": "normochromic-anemia",
        "name": "Normochromic anemia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/normochromic-anemia"
      },
      {
        "slug": "pallor",
        "name": "Paleness",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/pallor"
      },
      {
        "slug": "partial-duplication-of-thumb-phalanx",
        "name": "Partial duplication of the thumb bones",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/partial-duplication-of-thumb-phalanx"
      },
      {
        "slug": "persistence-of-hemoglobin-f",
        "name": "Persistence of hemoglobin F",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/persistence-of-hemoglobin-f"
      },
      {
        "slug": "pure-red-cell-aplasia",
        "name": "Pure red cell aplasia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/pure-red-cell-aplasia"
      },
      {
        "slug": "radial-artery-aplasia",
        "name": "Radial artery aplasia",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/radial-artery-aplasia"
      },
      {
        "slug": "reticulocytopenia",
        "name": "Reticulocytopenia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/reticulocytopenia"
      },
      {
        "slug": "short-neck",
        "name": "Short neck",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/short-neck"
      },
      {
        "slug": "short-stature",
        "name": "Short stature",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/short-stature"
      },
      {
        "slug": "short-thumb",
        "name": "Short thumb",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/short-thumb"
      },
      {
        "slug": "microtia",
        "name": "Small ears",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/microtia"
      },
      {
        "slug": "small-for-gestational-age",
        "name": "Small for gestational age",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/small-for-gestational-age"
      },
      {
        "slug": "steroid-responsive-anemia",
        "name": "Steroid-responsive anemia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/steroid-responsive-anemia"
      },
      {
        "slug": "webbed-neck",
        "name": "Webbed neck",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/webbed-neck"
      },
      {
        "slug": "wide-nasal-bridge",
        "name": "Wide nasal bridge",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/wide-nasal-bridge"
      },
      {
        "slug": "hypertelorism",
        "name": "Wide-set eyes",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/hypertelorism"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}