{
  "url": "https://dantelabs.com/pt/genes/ccdc91",
  "gene": {
    "slug": "ccdc91",
    "symbol": "CCDC91",
    "name": "coiled-coil domain containing 91",
    "hgnc": "HGNC:24855",
    "summary": null,
    "location": "12p11.22",
    "locusType": "gene with protein product",
    "aliases": [
      "p56",
      "FLJ11088",
      "DKFZp779L1558"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000123106",
    "entrezId": 55297,
    "omim": [
      "617366"
    ],
    "uniprot": [
      "Q7Z6B0"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "12",
      "start": 28190456,
      "end": 28550166,
      "strand": "+",
      "ensemblTranscript": "ENST00000536442.6",
      "refseqTranscript": "NM_018318.5",
      "ensemblProtein": "ENSP00000445660.2",
      "refseqProtein": "NP_060788.3",
      "exons": [
        {
          "start": 28190456,
          "end": 28190641
        },
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        },
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        },
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        },
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      ],
      "cds": {
        "start": 28257216,
        "end": 28549173
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    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "12",
      "start": 28286182,
      "end": 28732883,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 27830745,
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      "genes": [
        {
          "symbol": "PTHLH",
          "ensemblId": "ENSG00000087494",
          "biotype": "protein_coding",
          "start": 27958084,
          "end": 27972755,
          "strand": "-",
          "slug": "pthlh"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormality-of-the-lower-limb",
        "name": "Abnormality of the lower limb",
        "systems": [
          "abnormality-of-limbs"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/abnormality-of-the-lower-limb"
      },
      {
        "slug": "palmar-hyperhidrosis",
        "name": "Excessive sweating of hands",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/palmar-hyperhidrosis"
      },
      {
        "slug": "fragmented-elastic-fibers-in-the-dermis",
        "name": "Fragmented elastic fibers in the dermis",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/fragmented-elastic-fibers-in-the-dermis"
      },
      {
        "slug": "granulomatosis",
        "name": "Granulomatosis",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/granulomatosis"
      },
      {
        "slug": "hypergranulosis",
        "name": "Hypergranulosis",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hypergranulosis"
      },
      {
        "slug": "hyperkeratotic-papule",
        "name": "Hyperkeratotic papule",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/hyperkeratotic-papule"
      },
      {
        "slug": "orthokeratosis",
        "name": "Orthokeratosis",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/orthokeratosis"
      },
      {
        "slug": "piezogenic-pedal-papules",
        "name": "Piezogenic pedal papules",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/piezogenic-pedal-papules"
      },
      {
        "slug": "skin-plaque",
        "name": "Skin plaque",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/skin-plaque"
      },
      {
        "slug": "palmoplantar-hyperkeratosis",
        "name": "Thickening of the outer layer of the skin of the palms and soles",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-integument"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/palmoplantar-hyperkeratosis"
      },
      {
        "slug": "epidermal-acanthosis",
        "name": "Thickening of upper layer of skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/epidermal-acanthosis"
      },
      {
        "slug": "yellow-papule",
        "name": "Yellow papule",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/yellow-papule"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}