{
  "url": "https://dantelabs.com/traits/tuberous-xanthoma",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "tuberous-xanthoma",
    "id": "HP:0031290",
    "name": "Tuberous xanthoma",
    "definition": "A type of xanthoma characterized by a nodular form. Tuberous xanthomas are firm subcutaneous nodules,whereby the overlying skin can have red or red-yellow color changes.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "xanthomatosis",
        "name": "Yellow bumps of fatty deposits on skin",
        "url": "https://dantelabs.com/traits/xanthomatosis"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "lmf1",
        "symbol": "LMF1",
        "hgnc": "HGNC:14154",
        "name": "lipase maturation factor 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmf1"
      },
      {
        "slug": "apoe",
        "symbol": "APOE",
        "hgnc": "HGNC:613",
        "name": "apolipoprotein E",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/apoe"
      },
      {
        "slug": "abcg8",
        "symbol": "ABCG8",
        "hgnc": "HGNC:13887",
        "name": "ATP binding cassette subfamily G member 8",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/abcg8"
      },
      {
        "slug": "cyp27a1",
        "symbol": "CYP27A1",
        "hgnc": "HGNC:2605",
        "name": "cytochrome P450 family 27 subfamily A member 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cyp27a1"
      }
    ]
  }
}