{
  "url": "https://dantelabs.com/traits/retinal-flecks",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "retinal-flecks",
    "id": "HP:0012045",
    "name": "Retinal flecks",
    "definition": "Presence of multiple yellowish-white lesions of various size and configuration on the retina not related to vascular lesions.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "yellow-white-retinal-lesion",
        "name": "Yellow/white retinal lesion",
        "url": "https://dantelabs.com/traits/yellow-white-retinal-lesion"
      }
    ],
    "narrower": [
      {
        "slug": "fundus-albipunctatus",
        "name": "Fundus albipunctatus",
        "genes": 4,
        "url": "https://dantelabs.com/traits/fundus-albipunctatus"
      }
    ],
    "genes": [
      {
        "slug": "pla2g5",
        "symbol": "PLA2G5",
        "hgnc": "HGNC:9038",
        "name": "phospholipase A2 group V",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pla2g5"
      },
      {
        "slug": "rdh8",
        "symbol": "RDH8",
        "hgnc": "HGNC:14423",
        "name": "retinol dehydrogenase 8",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rdh8"
      },
      {
        "slug": "rpgrip1",
        "symbol": "RPGRIP1",
        "hgnc": "HGNC:13436",
        "name": "RPGR interacting protein 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rpgrip1"
      },
      {
        "slug": "ubap1l",
        "symbol": "UBAP1L",
        "hgnc": "HGNC:40028",
        "name": "ubiquitin associated protein 1 like",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ubap1l"
      },
      {
        "slug": "zfyve26",
        "symbol": "ZFYVE26",
        "hgnc": "HGNC:20761",
        "name": "zinc finger FYVE-type containing 26",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zfyve26"
      },
      {
        "slug": "col4a3",
        "symbol": "COL4A3",
        "hgnc": "HGNC:2204",
        "name": "collagen type IV alpha 3 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col4a3"
      },
      {
        "slug": "col4a4",
        "symbol": "COL4A4",
        "hgnc": "HGNC:2206",
        "name": "collagen type IV alpha 4 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col4a4"
      },
      {
        "slug": "col4a5",
        "symbol": "COL4A5",
        "hgnc": "HGNC:2207",
        "name": "collagen type IV alpha 5 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col4a5"
      },
      {
        "slug": "abca4",
        "symbol": "ABCA4",
        "hgnc": "HGNC:34",
        "name": "ATP binding cassette subfamily A member 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/abca4"
      },
      {
        "slug": "best1",
        "symbol": "BEST1",
        "hgnc": "HGNC:12703",
        "name": "bestrophin 1",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/best1"
      },
      {
        "slug": "prom1",
        "symbol": "PROM1",
        "hgnc": "HGNC:9454",
        "name": "prominin 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prom1"
      },
      {
        "slug": "prph2",
        "symbol": "PRPH2",
        "hgnc": "HGNC:9942",
        "name": "peripherin 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prph2"
      },
      {
        "slug": "rdh5",
        "symbol": "RDH5",
        "hgnc": "HGNC:9940",
        "name": "retinol dehydrogenase 5",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rdh5"
      },
      {
        "slug": "rho",
        "symbol": "RHO",
        "hgnc": "HGNC:10012",
        "name": "rhodopsin",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rho"
      },
      {
        "slug": "rlbp1",
        "symbol": "RLBP1",
        "hgnc": "HGNC:10024",
        "name": "retinaldehyde binding protein 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rlbp1"
      }
    ]
  }
}