{
  "url": "https://dantelabs.com/traits/psychosis",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "psychosis",
    "id": "HP:0000709",
    "name": "Psychosis",
    "definition": "A condition characterized by changes in personality and thought patterns, often accompanied by hallucinations and delusional beliefs, is known as psychosis.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-psychotic-pattern",
        "name": "Abnormal psychotic pattern",
        "url": "https://dantelabs.com/traits/abnormal-psychotic-pattern"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "lrrc7",
        "symbol": "LRRC7",
        "hgnc": "HGNC:18531",
        "name": "leucine rich repeat containing 7",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrrc7"
      },
      {
        "slug": "mmadhc",
        "symbol": "MMADHC",
        "hgnc": "HGNC:25221",
        "name": "metabolism of cobalamin associated D",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mmadhc"
      },
      {
        "slug": "notch3",
        "symbol": "NOTCH3",
        "hgnc": "HGNC:7883",
        "name": "notch receptor 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/notch3"
      },
      {
        "slug": "rfc4",
        "symbol": "RFC4",
        "hgnc": "HGNC:9972",
        "name": "replication factor C subunit 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rfc4"
      },
      {
        "slug": "tbc1d7",
        "symbol": "TBC1D7",
        "hgnc": "HGNC:21066",
        "name": "TBC1 domain family member 7",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbc1d7"
      },
      {
        "slug": "trrap",
        "symbol": "TRRAP",
        "hgnc": "HGNC:12347",
        "name": "transformation/transcription domain associated protein",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trrap"
      },
      {
        "slug": "unc13a",
        "symbol": "UNC13A",
        "hgnc": "HGNC:23150",
        "name": "unc-13 homolog A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/unc13a"
      },
      {
        "slug": "wfs1",
        "symbol": "WFS1",
        "hgnc": "HGNC:12762",
        "name": "wolframin ER transmembrane glycoprotein",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wfs1"
      },
      {
        "slug": "cmpk2",
        "symbol": "CMPK2",
        "hgnc": "HGNC:27015",
        "name": "cytidine/uridine monophosphate kinase 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cmpk2"
      },
      {
        "slug": "dnmt1",
        "symbol": "DNMT1",
        "hgnc": "HGNC:2976",
        "name": "DNA methyltransferase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnmt1"
      },
      {
        "slug": "h4c3",
        "symbol": "H4C3",
        "hgnc": "HGNC:4787",
        "name": "H4 clustered histone 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/h4c3"
      },
      {
        "slug": "jam2",
        "symbol": "JAM2",
        "hgnc": "HGNC:14686",
        "name": "junctional adhesion molecule 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/jam2"
      },
      {
        "slug": "magel2",
        "symbol": "MAGEL2",
        "hgnc": "HGNC:6814",
        "name": "MAGE family member L2",
        "frequency": "frequent",
        "diseases": 5,
        "url": "https://dantelabs.com/genes/magel2"
      },
      {
        "slug": "mt-co1",
        "symbol": "MT-CO1",
        "hgnc": "HGNC:7419",
        "name": "mitochondrially encoded cytochrome c oxidase I",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-co1"
      },
      {
        "slug": "mt-co2",
        "symbol": "MT-CO2",
        "hgnc": "HGNC:7421",
        "name": "mitochondrially encoded cytochrome c oxidase II",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-co2"
      },
      {
        "slug": "mt-co3",
        "symbol": "MT-CO3",
        "hgnc": "HGNC:7422",
        "name": "mitochondrially encoded cytochrome c oxidase III",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-co3"
      },
      {
        "slug": "mt-nd1",
        "symbol": "MT-ND1",
        "hgnc": "HGNC:7455",
        "name": "mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-nd1"
      },
      {
        "slug": "mt-nd4",
        "symbol": "MT-ND4",
        "hgnc": "HGNC:7459",
        "name": "mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-nd4"
      },
      {
        "slug": "mt-nd5",
        "symbol": "MT-ND5",
        "hgnc": "HGNC:7461",
        "name": "mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-nd5"
      },
      {
        "slug": "mt-nd6",
        "symbol": "MT-ND6",
        "hgnc": "HGNC:7462",
        "name": "mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-nd6"
      },
      {
        "slug": "mt-tf",
        "symbol": "MT-TF",
        "hgnc": "HGNC:7481",
        "name": "mitochondrially encoded tRNA-Phe (UUU/C)",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-tf"
      },
      {
        "slug": "mt-th",
        "symbol": "MT-TH",
        "hgnc": "HGNC:7487",
        "name": "mitochondrially encoded tRNA-His (CAU/C)",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-th"
      },
      {
        "slug": "mt-tl1",
        "symbol": "MT-TL1",
        "hgnc": "HGNC:7490",
        "name": "mitochondrially encoded tRNA-Leu (UUA/G) 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-tl1"
      },
      {
        "slug": "mt-tq",
        "symbol": "MT-TQ",
        "hgnc": "HGNC:7495",
        "name": "mitochondrially encoded tRNA-Gln (CAA/G)",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-tq"
      },
      {
        "slug": "mt-ts1",
        "symbol": "MT-TS1",
        "hgnc": "HGNC:7497",
        "name": "mitochondrially encoded tRNA-Ser (UCN) 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-ts1"
      },
      {
        "slug": "mt-ts2",
        "symbol": "MT-TS2",
        "hgnc": "HGNC:7498",
        "name": "mitochondrially encoded tRNA-Ser (AGU/C) 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-ts2"
      },
      {
        "slug": "mt-tw",
        "symbol": "MT-TW",
        "hgnc": "HGNC:7501",
        "name": "mitochondrially encoded tRNA-Trp (UGA/G)",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-tw"
      },
      {
        "slug": "myorg",
        "symbol": "MYORG",
        "hgnc": "HGNC:19918",
        "name": "myogenesis regulating glycosidase",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/myorg"
      },
      {
        "slug": "naa60",
        "symbol": "NAA60",
        "hgnc": "HGNC:25875",
        "name": "N-alpha-acetyltransferase 60, NatF catalytic subunit",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/naa60"
      },
      {
        "slug": "ndn",
        "symbol": "NDN",
        "hgnc": "HGNC:7675",
        "name": "necdin, MAGE family member",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/ndn"
      },
      {
        "slug": "ndp",
        "symbol": "NDP",
        "hgnc": "HGNC:7678",
        "name": "norrin cystine knot growth factor NDP",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ndp"
      },
      {
        "slug": "oca2",
        "symbol": "OCA2",
        "hgnc": "HGNC:8101",
        "name": "OCA2 melanosomal transmembrane protein",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/oca2"
      },
      {
        "slug": "pdgfb",
        "symbol": "PDGFB",
        "hgnc": "HGNC:8800",
        "name": "platelet derived growth factor subunit B",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/pdgfb"
      },
      {
        "slug": "pdgfrb",
        "symbol": "PDGFRB",
        "hgnc": "HGNC:8804",
        "name": "platelet derived growth factor receptor beta",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pdgfrb"
      },
      {
        "slug": "rrp12",
        "symbol": "RRP12",
        "hgnc": "HGNC:29100",
        "name": "ribosomal RNA processing 12 homolog",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rrp12"
      },
      {
        "slug": "slc20a2",
        "symbol": "SLC20A2",
        "hgnc": "HGNC:10947",
        "name": "solute carrier family 20 member 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/slc20a2"
      },
      {
        "slug": "snrpn",
        "symbol": "SNRPN",
        "hgnc": "HGNC:11164",
        "name": "small nuclear ribonucleoprotein polypeptide N",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/snrpn"
      },
      {
        "slug": "tpm2",
        "symbol": "TPM2",
        "hgnc": "HGNC:12011",
        "name": "tropomyosin 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tpm2"
      },
      {
        "slug": "wars2",
        "symbol": "WARS2",
        "hgnc": "HGNC:12730",
        "name": "tryptophanyl tRNA synthetase 2, mitochondrial",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wars2"
      },
      {
        "slug": "xpr1",
        "symbol": "XPR1",
        "hgnc": "HGNC:12827",
        "name": "xenotropic and polytropic retrovirus receptor 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/xpr1"
      },
      {
        "slug": "aars2",
        "symbol": "AARS2",
        "hgnc": "HGNC:21022",
        "name": "alanyl-tRNA synthetase 2, mitochondrial",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aars2"
      },
      {
        "slug": "acads",
        "symbol": "ACADS",
        "hgnc": "HGNC:90",
        "name": "acyl-CoA dehydrogenase short chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/acads"
      },
      {
        "slug": "aldh18a1",
        "symbol": "ALDH18A1",
        "hgnc": "HGNC:9722",
        "name": "aldehyde dehydrogenase 18 family member A1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aldh18a1"
      },
      {
        "slug": "asl",
        "symbol": "ASL",
        "hgnc": "HGNC:746",
        "name": "argininosuccinate lyase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/asl"
      },
      {
        "slug": "atp7b",
        "symbol": "ATP7B",
        "hgnc": "HGNC:870",
        "name": "ATPase copper transporting beta",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp7b"
      },
      {
        "slug": "atxn7",
        "symbol": "ATXN7",
        "hgnc": "HGNC:10560",
        "name": "ataxin 7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atxn7"
      },
      {
        "slug": "brd4",
        "symbol": "BRD4",
        "hgnc": "HGNC:13575",
        "name": "bromodomain containing 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brd4"
      },
      {
        "slug": "cacna1a",
        "symbol": "CACNA1A",
        "hgnc": "HGNC:1388",
        "name": "calcium voltage-gated channel subunit alpha1 A",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cacna1a"
      },
      {
        "slug": "cbs",
        "symbol": "CBS",
        "hgnc": "HGNC:1550",
        "name": "cystathionine beta-synthase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cbs"
      },
      {
        "slug": "chd2",
        "symbol": "CHD2",
        "hgnc": "HGNC:1917",
        "name": "chromodomain helicase DNA binding protein 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chd2"
      },
      {
        "slug": "chd8",
        "symbol": "CHD8",
        "hgnc": "HGNC:20153",
        "name": "chromodomain helicase DNA binding protein 8",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chd8"
      },
      {
        "slug": "chmp2b",
        "symbol": "CHMP2B",
        "hgnc": "HGNC:24537",
        "name": "charged multivesicular body protein 2B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chmp2b"
      },
      {
        "slug": "cltrn",
        "symbol": "CLTRN",
        "hgnc": "HGNC:29437",
        "name": "collectrin, amino acid transport regulator",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cltrn"
      },
      {
        "slug": "cpox",
        "symbol": "CPOX",
        "hgnc": "HGNC:2321",
        "name": "coproporphyrinogen oxidase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cpox"
      },
      {
        "slug": "cux2",
        "symbol": "CUX2",
        "hgnc": "HGNC:19347",
        "name": "cut like homeobox 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cux2"
      },
      {
        "slug": "dcaf17",
        "symbol": "DCAF17",
        "hgnc": "HGNC:25784",
        "name": "DDB1 and CUL4 associated factor 17",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dcaf17"
      },
      {
        "slug": "dnm1",
        "symbol": "DNM1",
        "hgnc": "HGNC:2972",
        "name": "dynamin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnm1"
      },
      {
        "slug": "ehmt1",
        "symbol": "EHMT1",
        "hgnc": "HGNC:24650",
        "name": "euchromatic histone lysine methyltransferase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ehmt1"
      },
      {
        "slug": "gabrb3",
        "symbol": "GABRB3",
        "hgnc": "HGNC:4083",
        "name": "gamma-aminobutyric acid type A receptor subunit beta3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gabrb3"
      },
      {
        "slug": "gclc",
        "symbol": "GCLC",
        "hgnc": "HGNC:4311",
        "name": "glutamate-cysteine ligase catalytic subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gclc"
      },
      {
        "slug": "grn",
        "symbol": "GRN",
        "hgnc": "HGNC:4601",
        "name": "granulin precursor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/grn"
      },
      {
        "slug": "herc2",
        "symbol": "HERC2",
        "hgnc": "HGNC:4868",
        "name": "HECT and RLD domain containing E3 ubiquitin protein ligase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/herc2"
      },
      {
        "slug": "irak1",
        "symbol": "IRAK1",
        "hgnc": "HGNC:6112",
        "name": "interleukin 1 receptor associated kinase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/irak1"
      },
      {
        "slug": "jarid2",
        "symbol": "JARID2",
        "hgnc": "HGNC:6196",
        "name": "jumonji and AT-rich interaction domain containing 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/jarid2"
      },
      {
        "slug": "kcnn2",
        "symbol": "KCNN2",
        "hgnc": "HGNC:6291",
        "name": "potassium calcium-activated channel subfamily N member 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnn2"
      },
      {
        "slug": "kcnt1",
        "symbol": "KCNT1",
        "hgnc": "HGNC:18865",
        "name": "potassium sodium-activated channel subfamily T member 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnt1"
      },
      {
        "slug": "kdm6b",
        "symbol": "KDM6B",
        "hgnc": "HGNC:29012",
        "name": "lysine demethylase 6B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdm6b"
      },
      {
        "slug": "mapk10",
        "symbol": "MAPK10",
        "hgnc": "HGNC:6872",
        "name": "mitogen-activated protein kinase 10",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mapk10"
      },
      {
        "slug": "mapt",
        "symbol": "MAPT",
        "hgnc": "HGNC:6893",
        "name": "microtubule associated protein tau",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mapt"
      },
      {
        "slug": "mecp2",
        "symbol": "MECP2",
        "hgnc": "HGNC:6990",
        "name": "methyl-CpG binding protein 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mecp2"
      },
      {
        "slug": "med12",
        "symbol": "MED12",
        "hgnc": "HGNC:11957",
        "name": "mediator complex subunit 12",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/med12"
      },
      {
        "slug": "mkrn3",
        "symbol": "MKRN3",
        "hgnc": "HGNC:7114",
        "name": "makorin ring finger protein 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mkrn3"
      },
      {
        "slug": "mthfr",
        "symbol": "MTHFR",
        "hgnc": "HGNC:7436",
        "name": "methylenetetrahydrofolate reductase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mthfr"
      },
      {
        "slug": "nit1",
        "symbol": "NIT1",
        "hgnc": "HGNC:7828",
        "name": "nitrilase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nit1"
      },
      {
        "slug": "npap1",
        "symbol": "NPAP1",
        "hgnc": "HGNC:1190",
        "name": "nuclear pore associated protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/npap1"
      },
      {
        "slug": "pak3",
        "symbol": "PAK3",
        "hgnc": "HGNC:8592",
        "name": "p21 (RAC1) activated kinase 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pak3"
      },
      {
        "slug": "pidd1",
        "symbol": "PIDD1",
        "hgnc": "HGNC:16491",
        "name": "p53-induced death domain protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pidd1"
      },
      {
        "slug": "prorp",
        "symbol": "PRORP",
        "hgnc": "HGNC:19958",
        "name": "protein only RNase P catalytic subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prorp"
      },
      {
        "slug": "psen1",
        "symbol": "PSEN1",
        "hgnc": "HGNC:9508",
        "name": "presenilin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/psen1"
      },
      {
        "slug": "pus3",
        "symbol": "PUS3",
        "hgnc": "HGNC:25461",
        "name": "pseudouridine synthase 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pus3"
      },
      {
        "slug": "pwar1",
        "symbol": "PWAR1",
        "hgnc": "HGNC:30089",
        "name": "Prader Willi/Angelman region RNA 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pwar1"
      },
      {
        "slug": "pwrn1",
        "symbol": "PWRN1",
        "hgnc": "HGNC:33235",
        "name": "Prader-Willi region non-protein coding RNA 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pwrn1"
      },
      {
        "slug": "rps6ka3",
        "symbol": "RPS6KA3",
        "hgnc": "HGNC:10432",
        "name": "ribosomal protein S6 kinase A3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rps6ka3"
      },
      {
        "slug": "sat1",
        "symbol": "SAT1",
        "hgnc": "HGNC:10540",
        "name": "spermidine/spermine N1-acetyltransferase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sat1"
      },
      {
        "slug": "scn1a",
        "symbol": "SCN1A",
        "hgnc": "HGNC:10585",
        "name": "sodium voltage-gated channel alpha subunit 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scn1a"
      },
      {
        "slug": "sim1",
        "symbol": "SIM1",
        "hgnc": "HGNC:10882",
        "name": "SIM bHLH transcription factor 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sim1"
      },
      {
        "slug": "slc25a13",
        "symbol": "SLC25A13",
        "hgnc": "HGNC:10983",
        "name": "solute carrier family 25 member 13",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc25a13"
      },
      {
        "slug": "slc6a19",
        "symbol": "SLC6A19",
        "hgnc": "HGNC:27960",
        "name": "solute carrier family 6 member 19",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/slc6a19"
      },
      {
        "slug": "smad4",
        "symbol": "SMAD4",
        "hgnc": "HGNC:6770",
        "name": "SMAD family member 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smad4"
      },
      {
        "slug": "snord115-1",
        "symbol": "SNORD115-1",
        "hgnc": "HGNC:33020",
        "name": "small nucleolar RNA, C/D box 115-1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/snord115-1"
      },
      {
        "slug": "snord116-1",
        "symbol": "SNORD116-1",
        "hgnc": "HGNC:33067",
        "name": "small nucleolar RNA, C/D box 116-1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/snord116-1"
      },
      {
        "slug": "sobp",
        "symbol": "SOBP",
        "hgnc": "HGNC:29256",
        "name": "sine oculis binding protein homolog",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sobp"
      },
      {
        "slug": "spart",
        "symbol": "SPART",
        "hgnc": "HGNC:18514",
        "name": "spartin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spart"
      },
      {
        "slug": "spg11",
        "symbol": "SPG11",
        "hgnc": "HGNC:11226",
        "name": "SPG11 vesicle trafficking associated, spatacsin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spg11"
      },
      {
        "slug": "spp1",
        "symbol": "SPP1",
        "hgnc": "HGNC:11255",
        "name": "secreted phosphoprotein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spp1"
      },
      {
        "slug": "sqstm1",
        "symbol": "SQSTM1",
        "hgnc": "HGNC:11280",
        "name": "sequestosome 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sqstm1"
      },
      {
        "slug": "srcap",
        "symbol": "SRCAP",
        "hgnc": "HGNC:16974",
        "name": "Snf2 related CREBBP activator protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/srcap"
      },
      {
        "slug": "stat4",
        "symbol": "STAT4",
        "hgnc": "HGNC:11365",
        "name": "signal transducer and activator of transcription 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/stat4"
      },
      {
        "slug": "tmem106b",
        "symbol": "TMEM106B",
        "hgnc": "HGNC:22407",
        "name": "transmembrane protein 106B",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tmem106b"
      },
      {
        "slug": "trem2",
        "symbol": "TREM2",
        "hgnc": "HGNC:17761",
        "name": "triggering receptor expressed on myeloid cells 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trem2"
      },
      {
        "slug": "trex1",
        "symbol": "TREX1",
        "hgnc": "HGNC:12269",
        "name": "three prime repair exonuclease 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/trex1"
      },
      {
        "slug": "upf3b",
        "symbol": "UPF3B",
        "hgnc": "HGNC:20439",
        "name": "UPF3B regulator of nonsense mediated mRNA decay",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/upf3b"
      },
      {
        "slug": "vcp",
        "symbol": "VCP",
        "hgnc": "HGNC:12666",
        "name": "valosin containing protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vcp"
      },
      {
        "slug": "zdhhc9",
        "symbol": "ZDHHC9",
        "hgnc": "HGNC:18475",
        "name": "zDHHC palmitoyltransferase 9",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zdhhc9"
      },
      {
        "slug": "zmym2",
        "symbol": "ZMYM2",
        "hgnc": "HGNC:12989",
        "name": "zinc finger MYM-type containing 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zmym2"
      },
      {
        "slug": "atrx",
        "symbol": "ATRX",
        "hgnc": "HGNC:886",
        "name": "ATRX chromatin remodeler",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atrx"
      },
      {
        "slug": "braf",
        "symbol": "BRAF",
        "hgnc": "HGNC:1097",
        "name": "B-Raf proto-oncogene, serine/threonine kinase",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/braf"
      },
      {
        "slug": "cdh23",
        "symbol": "CDH23",
        "hgnc": "HGNC:13733",
        "name": "cadherin related 23",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdh23"
      },
      {
        "slug": "ctsh",
        "symbol": "CTSH",
        "hgnc": "HGNC:2535",
        "name": "cathepsin H",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ctsh"
      },
      {
        "slug": "eif3f",
        "symbol": "EIF3F",
        "hgnc": "HGNC:3275",
        "name": "eukaryotic translation initiation factor 3 subunit F",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eif3f"
      },
      {
        "slug": "ftl",
        "symbol": "FTL",
        "hgnc": "HGNC:3999",
        "name": "ferritin light chain",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ftl"
      },
      {
        "slug": "hcrt",
        "symbol": "HCRT",
        "hgnc": "HGNC:4847",
        "name": "hypocretin neuropeptide precursor",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hcrt"
      },
      {
        "slug": "hla-dqb1",
        "symbol": "HLA-DQB1",
        "hgnc": "HGNC:4944",
        "name": "major histocompatibility complex, class II, DQ beta 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hla-dqb1"
      },
      {
        "slug": "hla-drb1",
        "symbol": "HLA-DRB1",
        "hgnc": "HGNC:4948",
        "name": "major histocompatibility complex, class II, DR beta 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hla-drb1"
      },
      {
        "slug": "mmachc",
        "symbol": "MMACHC",
        "hgnc": "HGNC:24525",
        "name": "metabolism of cobalamin associated C",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mmachc"
      },
      {
        "slug": "mog",
        "symbol": "MOG",
        "hgnc": "HGNC:7197",
        "name": "myelin oligodendrocyte glycoprotein",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mog"
      },
      {
        "slug": "nr3c1",
        "symbol": "NR3C1",
        "hgnc": "HGNC:7978",
        "name": "nuclear receptor subfamily 3 group C member 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nr3c1"
      },
      {
        "slug": "p2ry11",
        "symbol": "P2RY11",
        "hgnc": "HGNC:8540",
        "name": "purinergic receptor P2Y11",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/p2ry11"
      },
      {
        "slug": "pank2",
        "symbol": "PANK2",
        "hgnc": "HGNC:15894",
        "name": "pantothenate kinase 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pank2"
      },
      {
        "slug": "pcdh19",
        "symbol": "PCDH19",
        "hgnc": "HGNC:14270",
        "name": "protocadherin 19",
        "frequency": "very-rare",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pcdh19"
      },
      {
        "slug": "tnfsf4",
        "symbol": "TNFSF4",
        "hgnc": "HGNC:11934",
        "name": "TNF superfamily member 4",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnfsf4"
      },
      {
        "slug": "tp53",
        "symbol": "TP53",
        "hgnc": "HGNC:11998",
        "name": "tumor protein p53",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tp53"
      },
      {
        "slug": "usp48",
        "symbol": "USP48",
        "hgnc": "HGNC:18533",
        "name": "ubiquitin specific peptidase 48",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/usp48"
      },
      {
        "slug": "usp8",
        "symbol": "USP8",
        "hgnc": "HGNC:12631",
        "name": "ubiquitin specific peptidase 8",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/usp8"
      },
      {
        "slug": "znf365",
        "symbol": "ZNF365",
        "hgnc": "HGNC:18194",
        "name": "zinc finger protein 365",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znf365"
      },
      {
        "slug": "abcd1",
        "symbol": "ABCD1",
        "hgnc": "HGNC:61",
        "name": "ATP binding cassette subfamily D member 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/abcd1"
      },
      {
        "slug": "aldh5a1",
        "symbol": "ALDH5A1",
        "hgnc": "HGNC:408",
        "name": "aldehyde dehydrogenase 5 family member A1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aldh5a1"
      },
      {
        "slug": "cln3",
        "symbol": "CLN3",
        "hgnc": "HGNC:2074",
        "name": "CLN3 lysosomal/endosomal transmembrane protein, battenin",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cln3"
      },
      {
        "slug": "dnase1",
        "symbol": "DNASE1",
        "hgnc": "HGNC:2956",
        "name": "deoxyribonuclease 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnase1"
      },
      {
        "slug": "epm2a",
        "symbol": "EPM2A",
        "hgnc": "HGNC:3413",
        "name": "EPM2A glucan phosphatase, laforin",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/epm2a"
      },
      {
        "slug": "fcgr2a",
        "symbol": "FCGR2A",
        "hgnc": "HGNC:3616",
        "name": "Fc gamma receptor IIa",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fcgr2a"
      },
      {
        "slug": "fcgr2b",
        "symbol": "FCGR2B",
        "hgnc": "HGNC:3618",
        "name": "Fc gamma receptor IIb",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fcgr2b"
      },
      {
        "slug": "gnas",
        "symbol": "GNAS",
        "hgnc": "HGNC:4392",
        "name": "GNAS complex locus",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnas"
      },
      {
        "slug": "itm2b",
        "symbol": "ITM2B",
        "hgnc": "HGNC:6174",
        "name": "integral membrane protein 2B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/itm2b"
      },
      {
        "slug": "npc1",
        "symbol": "NPC1",
        "hgnc": "HGNC:7897",
        "name": "NPC intracellular cholesterol transporter 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/npc1"
      },
      {
        "slug": "npc2",
        "symbol": "NPC2",
        "hgnc": "HGNC:14537",
        "name": "NPC intracellular cholesterol transporter 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/npc2"
      },
      {
        "slug": "pah",
        "symbol": "PAH",
        "hgnc": "HGNC:8582",
        "name": "phenylalanine hydroxylase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pah"
      },
      {
        "slug": "pde11a",
        "symbol": "PDE11A",
        "hgnc": "HGNC:8773",
        "name": "phosphodiesterase 11A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pde11a"
      },
      {
        "slug": "ppox",
        "symbol": "PPOX",
        "hgnc": "HGNC:9280",
        "name": "protoporphyrinogen oxidase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppox"
      },
      {
        "slug": "prdm8",
        "symbol": "PRDM8",
        "hgnc": "HGNC:13993",
        "name": "PR/SET domain 8",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prdm8"
      },
      {
        "slug": "prkar1a",
        "symbol": "PRKAR1A",
        "hgnc": "HGNC:9388",
        "name": "protein kinase cAMP-dependent type I regulatory subunit alpha",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prkar1a"
      },
      {
        "slug": "prnp",
        "symbol": "PRNP",
        "hgnc": "HGNC:9449",
        "name": "prion protein (Kanno blood group)",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prnp"
      },
      {
        "slug": "slc12a6",
        "symbol": "SLC12A6",
        "hgnc": "HGNC:10914",
        "name": "solute carrier family 12 member 6",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc12a6"
      },
      {
        "slug": "ttc19",
        "symbol": "TTC19",
        "hgnc": "HGNC:26006",
        "name": "tetratricopeptide repeat domain 19",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ttc19"
      },
      {
        "slug": "twnk",
        "symbol": "TWNK",
        "hgnc": "HGNC:1160",
        "name": "twinkle mtDNA helicase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/twnk"
      },
      {
        "slug": "vps13a",
        "symbol": "VPS13A",
        "hgnc": "HGNC:1908",
        "name": "vacuolar protein sorting 13 homolog A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vps13a"
      },
      {
        "slug": "zfyve26",
        "symbol": "ZFYVE26",
        "hgnc": "HGNC:20761",
        "name": "zinc finger FYVE-type containing 26",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zfyve26"
      }
    ]
  }
}