{
  "url": "https://dantelabs.com/traits/multinucleated-erythroblast",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "multinucleated-erythroblast",
    "id": "HP:0034278",
    "name": "Multinucleated erythroblast",
    "definition": "Erythroblasts with multiple nuclei. Erythroblasts are nucleated precrusor cells of erythrocytes that are localized to the bone marrow. Normally, erythroblasts have a single nucleus. The abnormal finding of erythrocytes with two or more nuclei may be related to defects in cytokinesis.",
    "synonyms": [
      "Bone marrow: multinucleated erythroblasts",
      "Multinucleate erythroblast"
    ],
    "systems": [
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-erythroid-lineage-cell-morphology",
        "name": "Abnormal erythroid lineage cell morphology",
        "url": "https://dantelabs.com/traits/abnormal-erythroid-lineage-cell-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "cdin1",
        "symbol": "CDIN1",
        "hgnc": "HGNC:26929",
        "name": "CDAN1 interacting nuclease 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdin1"
      },
      {
        "slug": "kif23",
        "symbol": "KIF23",
        "hgnc": "HGNC:6392",
        "name": "kinesin family member 23",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kif23"
      }
    ]
  }
}