{
  "url": "https://dantelabs.com/traits/malar-prominence",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "malar-prominence",
    "id": "HP:0010620",
    "name": "Malar prominence",
    "definition": "Prominence of the malar process of the maxilla and infraorbital area appreciated in profile and from in front of the face.",
    "synonyms": [
      "Malar excess",
      "Malar hyperplasia",
      "Prominent malar region"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-zygomatic-bone-morphology",
        "name": "Abnormality of the cheekbone",
        "url": "https://dantelabs.com/traits/abnormal-zygomatic-bone-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "ctdp1",
        "symbol": "CTDP1",
        "hgnc": "HGNC:2498",
        "name": "CTD phosphatase 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ctdp1"
      },
      {
        "slug": "hdac8",
        "symbol": "HDAC8",
        "hgnc": "HGNC:13315",
        "name": "histone deacetylase 8",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hdac8"
      },
      {
        "slug": "las1l",
        "symbol": "LAS1L",
        "hgnc": "HGNC:25726",
        "name": "LAS1 like ribosome biogenesis factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/las1l"
      },
      {
        "slug": "nsmce2",
        "symbol": "NSMCE2",
        "hgnc": "HGNC:26513",
        "name": "NSE2 SUMO ligase component of SMC5/6 complex",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nsmce2"
      },
      {
        "slug": "xrcc4",
        "symbol": "XRCC4",
        "hgnc": "HGNC:12831",
        "name": "X-ray repair cross complementing 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/xrcc4"
      },
      {
        "slug": "hbb",
        "symbol": "HBB",
        "hgnc": "HGNC:4827",
        "name": "hemoglobin subunit beta",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/hbb"
      },
      {
        "slug": "nbn",
        "symbol": "NBN",
        "hgnc": "HGNC:7652",
        "name": "nibrin",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nbn"
      }
    ]
  }
}