{
  "url": "https://dantelabs.com/traits/hemolytic-anemia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hemolytic-anemia",
    "id": "HP:0001878",
    "name": "Hemolytic anemia",
    "definition": "A type of anemia caused by premature destruction of red blood cells (hemolysis).",
    "synonyms": [
      "Haemolytic anaemia",
      "Haemolytic anemia",
      "Hemolytic anaemia",
      "Increased hemolysis"
    ],
    "systems": [
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      }
    ],
    "broader": [
      {
        "slug": "anemia-due-to-reduced-life-span-of-red-cells",
        "name": "Anemia due to reduced life span of red cells",
        "url": "https://dantelabs.com/traits/anemia-due-to-reduced-life-span-of-red-cells"
      }
    ],
    "narrower": [
      {
        "slug": "autoimmune-hemolytic-anemia",
        "name": "Autoimmune hemolytic anemia",
        "genes": 48,
        "url": "https://dantelabs.com/traits/autoimmune-hemolytic-anemia"
      },
      {
        "slug": "microangiopathic-hemolytic-anemia",
        "name": "Microangiopathic hemolytic anemia",
        "genes": 15,
        "url": "https://dantelabs.com/traits/microangiopathic-hemolytic-anemia"
      },
      {
        "slug": "nonspherocytic-hemolytic-anemia",
        "name": "Nonspherocytic hemolytic anemia",
        "genes": 11,
        "url": "https://dantelabs.com/traits/nonspherocytic-hemolytic-anemia"
      },
      {
        "slug": "coombs-positive-hemolytic-anemia",
        "name": "Coombs-positive hemolytic anemia",
        "genes": 10,
        "url": "https://dantelabs.com/traits/coombs-positive-hemolytic-anemia"
      },
      {
        "slug": "congenital-hemolytic-anemia",
        "name": "Congenital hemolytic anemia",
        "genes": 8,
        "url": "https://dantelabs.com/traits/congenital-hemolytic-anemia"
      },
      {
        "slug": "spontaneous-hemolytic-crises",
        "name": "Spontaneous hemolytic crises",
        "genes": 7,
        "url": "https://dantelabs.com/traits/spontaneous-hemolytic-crises"
      },
      {
        "slug": "chronic-hemolytic-anemia",
        "name": "Chronic hemolytic anemia",
        "genes": 5,
        "url": "https://dantelabs.com/traits/chronic-hemolytic-anemia"
      },
      {
        "slug": "episodic-hemolytic-anemia",
        "name": "Episodic hemolytic anemia",
        "genes": 3,
        "url": "https://dantelabs.com/traits/episodic-hemolytic-anemia"
      },
      {
        "slug": "fava-bean-induced-hemolytic-anemia",
        "name": "Fava bean-induced hemolytic anemia",
        "genes": 3,
        "url": "https://dantelabs.com/traits/fava-bean-induced-hemolytic-anemia"
      },
      {
        "slug": "heinz-body-anemia",
        "name": "Heinz body anemia",
        "genes": 3,
        "url": "https://dantelabs.com/traits/heinz-body-anemia"
      },
      {
        "slug": "compensated-hemolytic-anemia",
        "name": "Compensated hemolytic anemia",
        "genes": 1,
        "url": "https://dantelabs.com/traits/compensated-hemolytic-anemia"
      },
      {
        "slug": "drug-sensitive-hemolytic-anemia",
        "name": "Drug-sensitive hemolytic anemia",
        "genes": 1,
        "url": "https://dantelabs.com/traits/drug-sensitive-hemolytic-anemia"
      },
      {
        "slug": "exercise-induced-hemolysis",
        "name": "Exercise-induced hemolysis",
        "genes": 1,
        "url": "https://dantelabs.com/traits/exercise-induced-hemolysis"
      },
      {
        "slug": "increased-red-cell-hemolysis-by-shear-stress",
        "name": "Increased red cell hemolysis by shear stress",
        "genes": 1,
        "url": "https://dantelabs.com/traits/increased-red-cell-hemolysis-by-shear-stress"
      }
    ],
    "genes": [
      {
        "slug": "ank1",
        "symbol": "ANK1",
        "hgnc": "HGNC:492",
        "name": "ankyrin 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ank1"
      },
      {
        "slug": "atp11c",
        "symbol": "ATP11C",
        "hgnc": "HGNC:13554",
        "name": "ATPase phospholipid transporting 11C (ATP11C blood group)",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp11c"
      },
      {
        "slug": "cdan1",
        "symbol": "CDAN1",
        "hgnc": "HGNC:1713",
        "name": "codanin 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdan1"
      },
      {
        "slug": "cybc1",
        "symbol": "CYBC1",
        "hgnc": "HGNC:28672",
        "name": "cytochrome b-245 chaperone 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cybc1"
      },
      {
        "slug": "gata1",
        "symbol": "GATA1",
        "hgnc": "HGNC:4170",
        "name": "GATA binding protein 1",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/gata1"
      },
      {
        "slug": "gclc",
        "symbol": "GCLC",
        "hgnc": "HGNC:4311",
        "name": "glutamate-cysteine ligase catalytic subunit",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gclc"
      },
      {
        "slug": "gss",
        "symbol": "GSS",
        "hgnc": "HGNC:4624",
        "name": "glutathione synthetase",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gss"
      },
      {
        "slug": "hmox1",
        "symbol": "HMOX1",
        "hgnc": "HGNC:5013",
        "name": "heme oxygenase 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/hmox1"
      },
      {
        "slug": "il2ra",
        "symbol": "IL2RA",
        "hgnc": "HGNC:6008",
        "name": "interleukin 2 receptor subunit alpha",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/il2ra"
      },
      {
        "slug": "kcnn4",
        "symbol": "KCNN4",
        "hgnc": "HGNC:6293",
        "name": "potassium calcium-activated channel subfamily N member 4",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/kcnn4"
      },
      {
        "slug": "klf1",
        "symbol": "KLF1",
        "hgnc": "HGNC:6345",
        "name": "KLF transcription factor 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/klf1"
      },
      {
        "slug": "nt5c3a",
        "symbol": "NT5C3A",
        "hgnc": "HGNC:17820",
        "name": "5'-nucleotidase, cytosolic IIIA",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nt5c3a"
      },
      {
        "slug": "pan2",
        "symbol": "PAN2",
        "hgnc": "HGNC:20074",
        "name": "poly(A) specific ribonuclease subunit PAN2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pan2"
      },
      {
        "slug": "pgk1",
        "symbol": "PGK1",
        "hgnc": "HGNC:8896",
        "name": "phosphoglycerate kinase 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pgk1"
      },
      {
        "slug": "pigt",
        "symbol": "PIGT",
        "hgnc": "HGNC:14938",
        "name": "phosphatidylinositol glycan anchor biosynthesis class T",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pigt"
      },
      {
        "slug": "rhag",
        "symbol": "RHAG",
        "hgnc": "HGNC:10006",
        "name": "Rh associated glycoprotein",
        "frequency": "obligate",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/rhag"
      },
      {
        "slug": "rhce",
        "symbol": "RHCE",
        "hgnc": "HGNC:10008",
        "name": "Rh blood group CcEe antigens",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/rhce"
      },
      {
        "slug": "slc2a1",
        "symbol": "SLC2A1",
        "hgnc": "HGNC:11005",
        "name": "solute carrier family 2 member 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/slc2a1"
      },
      {
        "slug": "slc4a1",
        "symbol": "SLC4A1",
        "hgnc": "HGNC:11027",
        "name": "solute carrier family 4 member 1 (Diego blood group)",
        "frequency": "obligate",
        "diseases": 6,
        "url": "https://dantelabs.com/genes/slc4a1"
      },
      {
        "slug": "sptb",
        "symbol": "SPTB",
        "hgnc": "HGNC:11274",
        "name": "spectrin beta, erythrocytic",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sptb"
      },
      {
        "slug": "cd46",
        "symbol": "CD46",
        "hgnc": "HGNC:6953",
        "name": "CD46 molecule",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cd46"
      },
      {
        "slug": "cfh",
        "symbol": "CFH",
        "hgnc": "HGNC:4883",
        "name": "complement factor H",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfh"
      },
      {
        "slug": "cfi",
        "symbol": "CFI",
        "hgnc": "HGNC:5394",
        "name": "complement factor I",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfi"
      },
      {
        "slug": "hbb",
        "symbol": "HBB",
        "hgnc": "HGNC:4827",
        "name": "hemoglobin subunit beta",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/hbb"
      },
      {
        "slug": "hellpar",
        "symbol": "HELLPAR",
        "hgnc": "HGNC:43984",
        "name": "HELLP associated long non-coding RNA",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hellpar"
      },
      {
        "slug": "nbn",
        "symbol": "NBN",
        "hgnc": "HGNC:7652",
        "name": "nibrin",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nbn"
      },
      {
        "slug": "piezo1",
        "symbol": "PIEZO1",
        "hgnc": "HGNC:28993",
        "name": "piezo type mechanosensitive ion channel component 1 (Er blood group)",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/piezo1"
      },
      {
        "slug": "piga",
        "symbol": "PIGA",
        "hgnc": "HGNC:8957",
        "name": "phosphatidylinositol glycan anchor biosynthesis class A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/piga"
      },
      {
        "slug": "rhd",
        "symbol": "RHD",
        "hgnc": "HGNC:10009",
        "name": "Rh blood group D antigen",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rhd"
      },
      {
        "slug": "abcg5",
        "symbol": "ABCG5",
        "hgnc": "HGNC:13886",
        "name": "ATP binding cassette subfamily G member 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/abcg5"
      },
      {
        "slug": "abcg8",
        "symbol": "ABCG8",
        "hgnc": "HGNC:13887",
        "name": "ATP binding cassette subfamily G member 8",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/abcg8"
      },
      {
        "slug": "aldoa",
        "symbol": "ALDOA",
        "hgnc": "HGNC:414",
        "name": "aldolase, fructose-bisphosphate A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aldoa"
      },
      {
        "slug": "atp7b",
        "symbol": "ATP7B",
        "hgnc": "HGNC:870",
        "name": "ATPase copper transporting beta",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/atp7b"
      },
      {
        "slug": "c1galt1c1",
        "symbol": "C1GALT1C1",
        "hgnc": "HGNC:24338",
        "name": "C1GALT1 specific chaperone 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/c1galt1c1"
      },
      {
        "slug": "def6",
        "symbol": "DEF6",
        "hgnc": "HGNC:2760",
        "name": "DEF6 guanine nucleotide exchange factor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/def6"
      },
      {
        "slug": "tpp2",
        "symbol": "TPP2",
        "hgnc": "HGNC:12016",
        "name": "tripeptidyl peptidase 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tpp2"
      },
      {
        "slug": "uros",
        "symbol": "UROS",
        "hgnc": "HGNC:12592",
        "name": "uroporphyrinogen III synthase",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/uros"
      },
      {
        "slug": "was",
        "symbol": "WAS",
        "hgnc": "HGNC:12731",
        "name": "WASP actin nucleation promoting factor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/was"
      },
      {
        "slug": "adar",
        "symbol": "ADAR",
        "hgnc": "HGNC:225",
        "name": "adenosine deaminase RNA specific",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adar"
      },
      {
        "slug": "bank1",
        "symbol": "BANK1",
        "hgnc": "HGNC:18233",
        "name": "B cell scaffold protein with ankyrin repeats 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bank1"
      },
      {
        "slug": "blk",
        "symbol": "BLK",
        "hgnc": "HGNC:1057",
        "name": "BLK proto-oncogene, Src family tyrosine kinase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/blk"
      },
      {
        "slug": "c4a",
        "symbol": "C4A",
        "hgnc": "HGNC:1323",
        "name": "complement C4A (Chido/Rodgers blood group)",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/c4a"
      },
      {
        "slug": "c4b",
        "symbol": "C4B",
        "hgnc": "HGNC:1324",
        "name": "complement C4B (Chido/Rodgers blood group)",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/c4b"
      },
      {
        "slug": "cr2",
        "symbol": "CR2",
        "hgnc": "HGNC:2336",
        "name": "complement C3d receptor 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cr2"
      },
      {
        "slug": "ctla4",
        "symbol": "CTLA4",
        "hgnc": "HGNC:2505",
        "name": "cytotoxic T-lymphocyte associated protein 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ctla4"
      },
      {
        "slug": "dgke",
        "symbol": "DGKE",
        "hgnc": "HGNC:2852",
        "name": "diacylglycerol kinase epsilon",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dgke"
      },
      {
        "slug": "dnase1",
        "symbol": "DNASE1",
        "hgnc": "HGNC:2956",
        "name": "deoxyribonuclease 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dnase1"
      },
      {
        "slug": "epb41",
        "symbol": "EPB41",
        "hgnc": "HGNC:3377",
        "name": "erythrocyte membrane protein band 4.1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/epb41"
      },
      {
        "slug": "ets1",
        "symbol": "ETS1",
        "hgnc": "HGNC:3488",
        "name": "ETS proto-oncogene 1, transcription factor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ets1"
      },
      {
        "slug": "fcgr2b",
        "symbol": "FCGR2B",
        "hgnc": "HGNC:3618",
        "name": "Fc gamma receptor IIb",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/fcgr2b"
      },
      {
        "slug": "fcgr3b",
        "symbol": "FCGR3B",
        "hgnc": "HGNC:3620",
        "name": "Fc gamma receptor IIIb",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fcgr3b"
      },
      {
        "slug": "gnb2",
        "symbol": "GNB2",
        "hgnc": "HGNC:4398",
        "name": "G protein subunit beta 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnb2"
      },
      {
        "slug": "gypc",
        "symbol": "GYPC",
        "hgnc": "HGNC:4704",
        "name": "glycophorin C (Gerbich blood group)",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gypc"
      },
      {
        "slug": "hgd",
        "symbol": "HGD",
        "hgnc": "HGNC:4892",
        "name": "homogentisate 1,2-dioxygenase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hgd"
      },
      {
        "slug": "hla-drb1",
        "symbol": "HLA-DRB1",
        "hgnc": "HGNC:4948",
        "name": "major histocompatibility complex, class II, DR beta 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/hla-drb1"
      },
      {
        "slug": "ifih1",
        "symbol": "IFIH1",
        "hgnc": "HGNC:18873",
        "name": "interferon induced with helicase C domain 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ifih1"
      },
      {
        "slug": "ighg1",
        "symbol": "IGHG1",
        "hgnc": "HGNC:5525",
        "name": "immunoglobulin heavy constant gamma 1 (G1m marker)",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ighg1"
      },
      {
        "slug": "il10",
        "symbol": "IL10",
        "hgnc": "HGNC:5962",
        "name": "interleukin 10",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/il10"
      },
      {
        "slug": "irak1",
        "symbol": "IRAK1",
        "hgnc": "HGNC:6112",
        "name": "interleukin 1 receptor associated kinase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/irak1"
      },
      {
        "slug": "irf5",
        "symbol": "IRF5",
        "hgnc": "HGNC:6120",
        "name": "interferon regulatory factor 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/irf5"
      },
      {
        "slug": "itgam",
        "symbol": "ITGAM",
        "hgnc": "HGNC:6149",
        "name": "integrin subunit alpha M",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/itgam"
      },
      {
        "slug": "jazf1",
        "symbol": "JAZF1",
        "hgnc": "HGNC:28917",
        "name": "JAZF zinc finger 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/jazf1"
      },
      {
        "slug": "kiaa0319l",
        "symbol": "KIAA0319L",
        "hgnc": "HGNC:30071",
        "name": "KIAA0319 like",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiaa0319l"
      },
      {
        "slug": "mecp2",
        "symbol": "MECP2",
        "hgnc": "HGNC:6990",
        "name": "methyl-CpG binding protein 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mecp2"
      },
      {
        "slug": "pdcd1",
        "symbol": "PDCD1",
        "hgnc": "HGNC:8760",
        "name": "programmed cell death 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pdcd1"
      },
      {
        "slug": "pgm3",
        "symbol": "PGM3",
        "hgnc": "HGNC:8907",
        "name": "phosphoglucomutase 3",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pgm3"
      },
      {
        "slug": "ptpn22",
        "symbol": "PTPN22",
        "hgnc": "HGNC:9652",
        "name": "protein tyrosine phosphatase non-receptor type 22",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptpn22"
      },
      {
        "slug": "pxk",
        "symbol": "PXK",
        "hgnc": "HGNC:23326",
        "name": "PX domain containing serine/threonine kinase like",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pxk"
      },
      {
        "slug": "rnu7-1",
        "symbol": "RNU7-1",
        "hgnc": "HGNC:34033",
        "name": "RNA, U7 small nuclear 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu7-1"
      },
      {
        "slug": "spp1",
        "symbol": "SPP1",
        "hgnc": "HGNC:11255",
        "name": "secreted phosphoprotein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spp1"
      },
      {
        "slug": "spta1",
        "symbol": "SPTA1",
        "hgnc": "HGNC:11272",
        "name": "spectrin alpha, erythrocytic 1",
        "frequency": "occasional",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/spta1"
      },
      {
        "slug": "stat4",
        "symbol": "STAT4",
        "hgnc": "HGNC:11365",
        "name": "signal transducer and activator of transcription 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/stat4"
      },
      {
        "slug": "tlr7",
        "symbol": "TLR7",
        "hgnc": "HGNC:15631",
        "name": "toll like receptor 7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tlr7"
      },
      {
        "slug": "tnfaip3",
        "symbol": "TNFAIP3",
        "hgnc": "HGNC:11896",
        "name": "TNF alpha induced protein 3",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tnfaip3"
      },
      {
        "slug": "tnfsf4",
        "symbol": "TNFSF4",
        "hgnc": "HGNC:11934",
        "name": "TNF superfamily member 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnfsf4"
      },
      {
        "slug": "tnip1",
        "symbol": "TNIP1",
        "hgnc": "HGNC:16903",
        "name": "TNFAIP3 interacting protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnip1"
      },
      {
        "slug": "trex1",
        "symbol": "TREX1",
        "hgnc": "HGNC:12269",
        "name": "three prime repair exonuclease 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/trex1"
      },
      {
        "slug": "ube2l3",
        "symbol": "UBE2L3",
        "hgnc": "HGNC:12488",
        "name": "ubiquitin conjugating enzyme E2 L3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ube2l3"
      },
      {
        "slug": "urod",
        "symbol": "UROD",
        "hgnc": "HGNC:12591",
        "name": "uroporphyrinogen decarboxylase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/urod"
      },
      {
        "slug": "btnl2",
        "symbol": "BTNL2",
        "hgnc": "HGNC:1142",
        "name": "butyrophilin like 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/btnl2"
      },
      {
        "slug": "ak1",
        "symbol": "AK1",
        "hgnc": "HGNC:361",
        "name": "adenylate kinase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ak1"
      },
      {
        "slug": "alad",
        "symbol": "ALAD",
        "hgnc": "HGNC:395",
        "name": "aminolevulinate dehydratase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alad"
      },
      {
        "slug": "cd40lg",
        "symbol": "CD40LG",
        "hgnc": "HGNC:11935",
        "name": "CD40 ligand",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cd40lg"
      },
      {
        "slug": "cd59",
        "symbol": "CD59",
        "hgnc": "HGNC:1689",
        "name": "CD59 molecule (CD59 blood group)",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cd59"
      },
      {
        "slug": "col4a1",
        "symbol": "COL4A1",
        "hgnc": "HGNC:2202",
        "name": "collagen type IV alpha 1 chain",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col4a1"
      },
      {
        "slug": "cpox",
        "symbol": "CPOX",
        "hgnc": "HGNC:2321",
        "name": "coproporphyrinogen oxidase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cpox"
      },
      {
        "slug": "epb42",
        "symbol": "EPB42",
        "hgnc": "HGNC:3381",
        "name": "erythrocyte membrane protein band 4.2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/epb42"
      },
      {
        "slug": "fcgr2a",
        "symbol": "FCGR2A",
        "hgnc": "HGNC:3616",
        "name": "Fc gamma receptor IIa",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fcgr2a"
      },
      {
        "slug": "fech",
        "symbol": "FECH",
        "hgnc": "HGNC:3647",
        "name": "ferrochelatase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fech"
      },
      {
        "slug": "galt",
        "symbol": "GALT",
        "hgnc": "HGNC:4135",
        "name": "galactose-1-phosphate uridylyltransferase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/galt"
      },
      {
        "slug": "gp1ba",
        "symbol": "GP1BA",
        "hgnc": "HGNC:4439",
        "name": "glycoprotein Ib platelet subunit alpha",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gp1ba"
      },
      {
        "slug": "hba1",
        "symbol": "HBA1",
        "hgnc": "HGNC:4823",
        "name": "hemoglobin subunit alpha 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hba1"
      },
      {
        "slug": "hba2",
        "symbol": "HBA2",
        "hgnc": "HGNC:4824",
        "name": "hemoglobin subunit alpha 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hba2"
      },
      {
        "slug": "kdm6a",
        "symbol": "KDM6A",
        "hgnc": "HGNC:12637",
        "name": "lysine demethylase 6A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdm6a"
      },
      {
        "slug": "kmt2d",
        "symbol": "KMT2D",
        "hgnc": "HGNC:7133",
        "name": "lysine methyltransferase 2D",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kmt2d"
      },
      {
        "slug": "lcat",
        "symbol": "LCAT",
        "hgnc": "HGNC:6522",
        "name": "lecithin-cholesterol acyltransferase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lcat"
      },
      {
        "slug": "nras",
        "symbol": "NRAS",
        "hgnc": "HGNC:7989",
        "name": "NRAS proto-oncogene, GTPase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nras"
      },
      {
        "slug": "pfkm",
        "symbol": "PFKM",
        "hgnc": "HGNC:8877",
        "name": "phosphofructokinase, muscle",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pfkm"
      },
      {
        "slug": "tpi1",
        "symbol": "TPI1",
        "hgnc": "HGNC:12009",
        "name": "triosephosphate isomerase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tpi1"
      }
    ]
  }
}