{
  "url": "https://dantelabs.com/traits/duodenitis",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "duodenitis",
    "id": "HP:0033117",
    "name": "Duodenitis",
    "definition": "Inflammation of the lining of the upper small intestine (duodenum).",
    "synonyms": [
      "Duodenal inflammation"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-duodenum-morphology",
        "name": "Abnormal duodenum morphology",
        "url": "https://dantelabs.com/traits/abnormal-duodenum-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "adam17",
        "symbol": "ADAM17",
        "hgnc": "HGNC:195",
        "name": "ADAM metallopeptidase domain 17",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adam17"
      },
      {
        "slug": "flt3lg",
        "symbol": "FLT3LG",
        "hgnc": "HGNC:3766",
        "name": "fms related receptor tyrosine kinase 3 ligand",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flt3lg"
      },
      {
        "slug": "irf4",
        "symbol": "IRF4",
        "hgnc": "HGNC:6119",
        "name": "interferon regulatory factor 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/irf4"
      },
      {
        "slug": "ptcra",
        "symbol": "PTCRA",
        "hgnc": "HGNC:21290",
        "name": "pre T cell antigen receptor alpha",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptcra"
      },
      {
        "slug": "ipo8",
        "symbol": "IPO8",
        "hgnc": "HGNC:9853",
        "name": "importin 8",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ipo8"
      },
      {
        "slug": "card8",
        "symbol": "CARD8",
        "hgnc": "HGNC:17057",
        "name": "caspase recruitment domain family member 8",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/card8"
      }
    ]
  }
}