{
  "url": "https://dantelabs.com/traits/c3-nephritic-factor-positivity",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "c3-nephritic-factor-positivity",
    "id": "HP:0030888",
    "name": "C3 nephritic factor positivity",
    "definition": "The presence of autoantibodies (immunoglobulins) in the serum that react against C3 convertase (C3bBb).",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "autoimmune-antibody-positivity",
        "name": "Autoimmune antibody positivity",
        "url": "https://dantelabs.com/traits/autoimmune-antibody-positivity"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "dgke",
        "symbol": "DGKE",
        "hgnc": "HGNC:2852",
        "name": "diacylglycerol kinase epsilon",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dgke"
      }
    ]
  }
}