{
  "url": "https://dantelabs.com/traits/abnormal-pons-morphology",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-pons-morphology",
    "id": "HP:0007361",
    "name": "Abnormal pons morphology",
    "definition": "A structural abnormality of the pons.",
    "synonyms": [
      "Abnormality of the pons"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-metencephalon-morphology",
        "name": "Abnormal metencephalon morphology",
        "url": "https://dantelabs.com/traits/abnormal-metencephalon-morphology"
      },
      {
        "slug": "abnormal-brainstem-morphology",
        "name": "Abnormal shape of brainstem",
        "url": "https://dantelabs.com/traits/abnormal-brainstem-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "hypoplasia-of-the-pons",
        "name": "Hypoplasia of the pons",
        "genes": 92,
        "url": "https://dantelabs.com/traits/hypoplasia-of-the-pons"
      },
      {
        "slug": "pontocerebellar-atrophy",
        "name": "Pontocerebellar atrophy",
        "genes": 9,
        "url": "https://dantelabs.com/traits/pontocerebellar-atrophy"
      },
      {
        "slug": "abnormal-superior-cerebellar-peduncle-morphology",
        "name": "Abnormal superior cerebellar peduncle morphology",
        "genes": 1,
        "url": "https://dantelabs.com/traits/abnormal-superior-cerebellar-peduncle-morphology"
      },
      {
        "slug": "hot-cross-bun-sign",
        "name": "Hot cross bun sign",
        "genes": 1,
        "url": "https://dantelabs.com/traits/hot-cross-bun-sign"
      },
      {
        "slug": "pontine-t2-hypointensity",
        "name": "Pontine T2 hypointensity",
        "genes": 1,
        "url": "https://dantelabs.com/traits/pontine-t2-hypointensity"
      }
    ],
    "genes": [
      {
        "slug": "dag1",
        "symbol": "DAG1",
        "hgnc": "HGNC:2666",
        "name": "dystroglycan 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dag1"
      },
      {
        "slug": "galc",
        "symbol": "GALC",
        "hgnc": "HGNC:4115",
        "name": "galactosylceramidase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/galc"
      },
      {
        "slug": "sacs",
        "symbol": "SACS",
        "hgnc": "HGNC:10519",
        "name": "sacsin molecular chaperone",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sacs"
      },
      {
        "slug": "fkrp",
        "symbol": "FKRP",
        "hgnc": "HGNC:17997",
        "name": "fukutin related protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fkrp"
      },
      {
        "slug": "gmppb",
        "symbol": "GMPPB",
        "hgnc": "HGNC:22932",
        "name": "GDP-mannose pyrophosphorylase B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gmppb"
      },
      {
        "slug": "idh1",
        "symbol": "IDH1",
        "hgnc": "HGNC:5382",
        "name": "isocitrate dehydrogenase (NADP(+)) 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/idh1"
      },
      {
        "slug": "large1",
        "symbol": "LARGE1",
        "hgnc": "HGNC:6511",
        "name": "LARGE xylosyl- and glucuronyltransferase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/large1"
      },
      {
        "slug": "pomt1",
        "symbol": "POMT1",
        "hgnc": "HGNC:9202",
        "name": "protein O-mannosyltransferase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pomt1"
      },
      {
        "slug": "pomt2",
        "symbol": "POMT2",
        "hgnc": "HGNC:19743",
        "name": "protein O-mannosyltransferase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pomt2"
      },
      {
        "slug": "piga",
        "symbol": "PIGA",
        "hgnc": "HGNC:8957",
        "name": "phosphatidylinositol glycan anchor biosynthesis class A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/piga"
      }
    ]
  }
}