{
  "url": "https://dantelabs.com/traits/abnormal-lymphocyte-physiology",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-lymphocyte-physiology",
    "id": "HP:0031409",
    "name": "Abnormal lymphocyte physiology",
    "definition": "Any anomaly of lymphocyte function.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormal-cellular-phenotype",
        "name": "Abnormal cellular phenotype",
        "url": "https://dantelabs.com/traits/abnormal-cellular-phenotype"
      },
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      },
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-cellular-physiology",
        "name": "Abnormal cellular physiology",
        "url": "https://dantelabs.com/traits/abnormal-cellular-physiology"
      },
      {
        "slug": "abnormal-leukocyte-physiology",
        "name": "Abnormal leukocyte physiology",
        "url": "https://dantelabs.com/traits/abnormal-leukocyte-physiology"
      }
    ],
    "narrower": [
      {
        "slug": "abnormal-t-cell-physiology",
        "name": "Impaired T cell function",
        "genes": 31,
        "url": "https://dantelabs.com/traits/abnormal-t-cell-physiology"
      },
      {
        "slug": "abnormal-natural-killer-cell-physiology",
        "name": "Abnormal natural killer cell physiology",
        "genes": 16,
        "url": "https://dantelabs.com/traits/abnormal-natural-killer-cell-physiology"
      },
      {
        "slug": "abnormal-lymphocyte-proliferation",
        "name": "Abnormal lymphocyte proliferation",
        "genes": 2,
        "url": "https://dantelabs.com/traits/abnormal-lymphocyte-proliferation"
      },
      {
        "slug": "abnormal-b-cell-physiology",
        "name": "Abnormality of B cell physiology",
        "genes": 2,
        "url": "https://dantelabs.com/traits/abnormal-b-cell-physiology"
      }
    ],
    "genes": [
      {
        "slug": "smarcal1",
        "symbol": "SMARCAL1",
        "hgnc": "HGNC:11102",
        "name": "SNF2 related chromatin remodeling annealing helicase 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smarcal1"
      },
      {
        "slug": "lmna",
        "symbol": "LMNA",
        "hgnc": "HGNC:6636",
        "name": "lamin A/C",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmna"
      }
    ]
  }
}