{
  "url": "https://dantelabs.com/pl/genes/pikfyve",
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          "symbol": "PLEKHM3",
          "ensemblId": "ENSG00000178385",
          "biotype": "protein_coding",
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          "strand": "-",
          "slug": "plekhm3"
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        {
          "symbol": "CRYGD",
          "ensemblId": "ENSG00000118231",
          "biotype": "protein_coding",
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        {
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          "ensemblId": "ENSG00000163254",
          "biotype": "protein_coding",
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          "strand": "-",
          "slug": "crygc"
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        {
          "symbol": "CRYGB",
          "ensemblId": "ENSG00000182187",
          "biotype": "protein_coding",
          "start": 208142573,
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          "strand": "-",
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        {
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          "ensemblId": "ENSG00000168582",
          "biotype": "protein_coding",
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          "strand": "-",
          "slug": "cryga"
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        {
          "symbol": "C2orf80",
          "ensemblId": "ENSG00000188674",
          "biotype": "protein_coding",
          "start": 208165343,
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          "strand": "-",
          "slug": "c2orf80"
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        {
          "symbol": "IDH1",
          "ensemblId": "ENSG00000138413",
          "biotype": "protein_coding",
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          "strand": "-",
          "slug": "idh1"
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        {
          "symbol": "PTH2R",
          "ensemblId": "ENSG00000144407",
          "biotype": "protein_coding",
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          "strand": "+",
          "slug": "pth2r"
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      ],
      "truncated": false
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    "reports": [
      {
        "slug": "hereditary-corneal-dystrophies",
        "name": "Dziedziczne dystrofie rogówki",
        "diseases": [
          {
            "mondoId": "MONDO:0018102",
            "name": "Dystrofia rogówki",
            "genes": 19,
            "inheritance": null,
            "description": "Grupa dziedzicznych schorzeń dotyczących jednej lub kilku warstw rogówki, m.in. dystrofia śródbłonka Fuchsa (często związana z ekspansją powtórzeń w genie TCF4), ziarnista i siateczkowa dystrofia związana z genem TGFBI oraz rzadsze postacie wywoływane przez geny takie jak SLC4A11, COL8A2, ZEB1 i CHST6.",
            "management": "Osobom, u których wykryto warianty w genie TGFBI, zazwyczaj zaleca się unikanie laserowych zabiegów refrakcyjnych (LASIK lub PRK), ponieważ mogą one nasilić złogi. W zaawansowanej chorobie przeszczep rogówki może przywrócić widzenie.",
            "evidence": {
              "gencc": [
                "G2P",
                "Labcorp Genetics (formerly Invitae)",
                "PanelApp Australia"
              ],
              "acmgSf": false,
              "inheritance": [
                "autosomal-dominant"
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            },
            "sameAsReport": false,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/pl/conditions/hereditary-corneal-dystrophies"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "photophobia",
        "name": "Extreme sensitivity of the eyes to light",
        "systems": [
          "abnormality-of-the-eye",
          "abnormality-of-the-nervous-system"
        ],
        "url": "https://dantelabs.com/traits/photophobia"
      },
      {
        "slug": "speckled-corneal-dystrophy",
        "name": "Speckled corneal dystrophy",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "url": "https://dantelabs.com/traits/speckled-corneal-dystrophy"
      }
    ],
    "related": [
      {
        "slug": "chst6",
        "symbol": "CHST6",
        "name": "carbohydrate sulfotransferase 6",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/chst6"
      },
      {
        "slug": "col17a1",
        "symbol": "COL17A1",
        "name": "collagen type XVII alpha 1 chain",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/col17a1"
      },
      {
        "slug": "col8a2",
        "symbol": "COL8A2",
        "name": "collagen type VIII alpha 2 chain",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/col8a2"
      },
      {
        "slug": "dcn",
        "symbol": "DCN",
        "name": "decorin",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/dcn"
      },
      {
        "slug": "grhl2",
        "symbol": "GRHL2",
        "name": "grainyhead like transcription factor 2",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/grhl2"
      },
      {
        "slug": "gsn",
        "symbol": "GSN",
        "name": "gelsolin",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/gsn"
      },
      {
        "slug": "krt12",
        "symbol": "KRT12",
        "name": "keratin 12",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/krt12"
      },
      {
        "slug": "krt3",
        "symbol": "KRT3",
        "name": "keratin 3",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/krt3"
      },
      {
        "slug": "mcoln1",
        "symbol": "MCOLN1",
        "name": "mucolipin TRP cation channel 1",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/mcoln1"
      },
      {
        "slug": "nlrp1",
        "symbol": "NLRP1",
        "name": "NLR family pyrin domain containing 1",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/nlrp1"
      },
      {
        "slug": "ovol2",
        "symbol": "OVOL2",
        "name": "ovo like zinc finger 2",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/ovol2"
      },
      {
        "slug": "prdx3",
        "symbol": "PRDX3",
        "name": "peroxiredoxin 3",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/prdx3"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}