{
  "url": "https://dantelabs.com/pl/genes/foxj1",
  "gene": {
    "slug": "foxj1",
    "symbol": "FOXJ1",
    "name": "forkhead box J1",
    "hgnc": "HGNC:3816",
    "summary": null,
    "location": "17q25.1",
    "locusType": "gene with protein product",
    "aliases": [
      "HFH-4",
      "HFH4"
    ],
    "previousSymbols": [
      "FKHL13"
    ],
    "ensemblId": "ENSG00000129654",
    "entrezId": 2302,
    "omim": [
      "602291"
    ],
    "uniprot": [
      "Q92949"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "17",
      "start": 76136333,
      "end": 76141245,
      "strand": "-",
      "ensemblTranscript": "ENST00000322957.7",
      "refseqTranscript": "NM_001454.4",
      "ensemblProtein": "ENSP00000323880.4",
      "refseqProtein": "NP_001445.2",
      "exons": [
        {
          "start": 76136333,
          "end": 76138120
        },
        {
          "start": 76139898,
          "end": 76140564
        },
        {
          "start": 76141114,
          "end": 76141245
        }
      ],
      "cds": {
        "start": 76137353,
        "end": 76140395
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "17",
      "start": 74132414,
      "end": 74137380,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 75638789,
      "end": 76638788,
      "genes": [
        {
          "symbol": "RECQL5",
          "ensemblId": "ENSG00000108469",
          "biotype": "protein_coding",
          "start": 75626839,
          "end": 75667197,
          "strand": "-",
          "slug": "recql5"
        },
        {
          "symbol": "SMIM5",
          "ensemblId": "ENSG00000204323",
          "biotype": "protein_coding",
          "start": 75628368,
          "end": 75642570,
          "strand": "+",
          "slug": "smim5"
        },
        {
          "symbol": "ERLN",
          "ensemblId": "ENSG00000259120",
          "biotype": "protein_coding",
          "start": 75646243,
          "end": 75647975,
          "strand": "+",
          "slug": "erln"
        },
        {
          "symbol": "SAP30BP",
          "ensemblId": "ENSG00000161526",
          "biotype": "protein_coding",
          "start": 75667230,
          "end": 75708062,
          "strand": "+",
          "slug": "sap30bp"
        },
        {
          "symbol": "ITGB4",
          "ensemblId": "ENSG00000132470",
          "biotype": "protein_coding",
          "start": 75721190,
          "end": 75757821,
          "strand": "+",
          "slug": "itgb4"
        },
        {
          "symbol": "GALK1",
          "ensemblId": "ENSG00000108479",
          "biotype": "protein_coding",
          "start": 75751470,
          "end": 75765251,
          "strand": "-",
          "slug": "galk1"
        },
        {
          "symbol": "H3-3B",
          "ensemblId": "ENSG00000132475",
          "biotype": "protein_coding",
          "start": 75776434,
          "end": 75785893,
          "strand": "-",
          "slug": "h3-3b"
        },
        {
          "symbol": "UNK",
          "ensemblId": "ENSG00000132478",
          "biotype": "protein_coding",
          "start": 75784799,
          "end": 75825799,
          "strand": "+",
          "slug": "unk"
        },
        {
          "symbol": "UNC13D",
          "ensemblId": "ENSG00000092929",
          "biotype": "protein_coding",
          "start": 75827032,
          "end": 75845353,
          "strand": "-",
          "slug": "unc13d"
        },
        {
          "symbol": "WBP2",
          "ensemblId": "ENSG00000132471",
          "biotype": "protein_coding",
          "start": 75845699,
          "end": 75856507,
          "strand": "-",
          "slug": "wbp2"
        },
        {
          "symbol": "TRIM47",
          "ensemblId": "ENSG00000132481",
          "biotype": "protein_coding",
          "start": 75874161,
          "end": 75878637,
          "strand": "-",
          "slug": "trim47"
        },
        {
          "symbol": "TRIM65",
          "ensemblId": "ENSG00000141569",
          "biotype": "protein_coding",
          "start": 75879538,
          "end": 75897018,
          "strand": "-",
          "slug": "trim65"
        },
        {
          "symbol": "MRPL38",
          "ensemblId": "ENSG00000204316",
          "biotype": "protein_coding",
          "start": 75898642,
          "end": 75905097,
          "strand": "-",
          "slug": "mrpl38"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000267426",
          "biotype": "protein_coding",
          "start": 75898645,
          "end": 75930129,
          "strand": "-"
        },
        {
          "symbol": "FBF1",
          "ensemblId": "ENSG00000188878",
          "biotype": "protein_coding",
          "start": 75908212,
          "end": 75941140,
          "strand": "-",
          "slug": "fbf1"
        },
        {
          "symbol": "ACOX1",
          "ensemblId": "ENSG00000161533",
          "biotype": "protein_coding",
          "start": 75941507,
          "end": 75979459,
          "strand": "-",
          "slug": "acox1"
        },
        {
          "symbol": "TEN1",
          "ensemblId": "ENSG00000257949",
          "biotype": "protein_coding",
          "start": 75979212,
          "end": 76000587,
          "strand": "+",
          "slug": "ten1"
        },
        {
          "symbol": "TEN1-CDK3",
          "ensemblId": "ENSG00000261408",
          "biotype": "protein_coding",
          "start": 75979231,
          "end": 76005999,
          "strand": "+",
          "slug": "ten1-cdk3"
        },
        {
          "symbol": "CDK3",
          "ensemblId": "ENSG00000250506",
          "biotype": "protein_coding",
          "start": 76000644,
          "end": 76005999,
          "strand": "+",
          "slug": "cdk3"
        },
        {
          "symbol": "EVPL",
          "ensemblId": "ENSG00000167880",
          "biotype": "protein_coding",
          "start": 76004379,
          "end": 76027465,
          "strand": "-",
          "slug": "evpl"
        },
        {
          "symbol": "SRP68",
          "ensemblId": "ENSG00000167881",
          "biotype": "protein_coding",
          "start": 76037989,
          "end": 76072718,
          "strand": "-",
          "slug": "srp68"
        },
        {
          "symbol": "ZACN",
          "ensemblId": "ENSG00000186919",
          "biotype": "protein_coding",
          "start": 76071961,
          "end": 76083666,
          "strand": "+",
          "slug": "zacn"
        },
        {
          "symbol": "GALR2",
          "ensemblId": "ENSG00000182687",
          "biotype": "protein_coding",
          "start": 76074773,
          "end": 76077537,
          "strand": "+",
          "slug": "galr2"
        },
        {
          "symbol": "EXOC7",
          "ensemblId": "ENSG00000182473",
          "biotype": "protein_coding",
          "start": 76080995,
          "end": 76121576,
          "strand": "-",
          "slug": "exoc7"
        },
        {
          "symbol": "RNF157",
          "ensemblId": "ENSG00000141576",
          "biotype": "protein_coding",
          "start": 76142460,
          "end": 76240662,
          "strand": "-",
          "slug": "rnf157"
        },
        {
          "symbol": "UBALD2",
          "ensemblId": "ENSG00000185262",
          "biotype": "protein_coding",
          "start": 76265197,
          "end": 76271298,
          "strand": "+",
          "slug": "ubald2"
        },
        {
          "symbol": "QRICH2",
          "ensemblId": "ENSG00000129646",
          "biotype": "protein_coding",
          "start": 76274049,
          "end": 76308282,
          "strand": "-",
          "slug": "qrich2"
        },
        {
          "symbol": "PRPSAP1",
          "ensemblId": "ENSG00000161542",
          "biotype": "protein_coding",
          "start": 76309478,
          "end": 76384521,
          "strand": "-",
          "slug": "prpsap1"
        },
        {
          "symbol": "SPHK1",
          "ensemblId": "ENSG00000176170",
          "biotype": "protein_coding",
          "start": 76376584,
          "end": 76387860,
          "strand": "+",
          "slug": "sphk1"
        },
        {
          "symbol": "UBE2O",
          "ensemblId": "ENSG00000175931",
          "biotype": "protein_coding",
          "start": 76389456,
          "end": 76453226,
          "strand": "-",
          "slug": "ube2o"
        },
        {
          "symbol": "AANAT",
          "ensemblId": "ENSG00000129673",
          "biotype": "protein_coding",
          "start": 76452749,
          "end": 76470122,
          "strand": "+",
          "slug": "aanat"
        },
        {
          "symbol": "RHBDF2",
          "ensemblId": "ENSG00000129667",
          "biotype": "protein_coding",
          "start": 76470884,
          "end": 76501790,
          "strand": "-",
          "slug": "rhbdf2"
        },
        {
          "symbol": "CYGB",
          "ensemblId": "ENSG00000161544",
          "biotype": "protein_coding",
          "start": 76527356,
          "end": 76551175,
          "strand": "-",
          "slug": "cygb"
        },
        {
          "symbol": "PRCD",
          "ensemblId": "ENSG00000214140",
          "biotype": "protein_coding",
          "start": 76527586,
          "end": 76553578,
          "strand": "+",
          "slug": "prcd"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000284526",
          "biotype": "protein_coding",
          "start": 76563710,
          "end": 76569724,
          "strand": "-"
        },
        {
          "symbol": "ST6GALNAC2",
          "ensemblId": "ENSG00000070731",
          "biotype": "protein_coding",
          "start": 76564424,
          "end": 76586956,
          "strand": "-",
          "slug": "st6galnac2"
        },
        {
          "symbol": "ST6GALNAC1",
          "ensemblId": "ENSG00000070526",
          "biotype": "protein_coding",
          "start": 76624228,
          "end": 76643907,
          "strand": "-",
          "slug": "st6galnac1"
        }
      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "primary-ciliary-dyskinesia",
        "name": "Dyskinezja rzęsek pierwotna",
        "diseases": [
          {
            "mondoId": "MONDO:0016575",
            "name": "Dyskinezja rzęsek pierwotna",
            "genes": 50,
            "inheritance": "autosomal-recessive",
            "description": "Rzadka, genetycznie heterogenna choroba, przede wszystkim układu oddechowego, charakteryzująca się przewlekłymi chorobami górnych i dolnych dróg oddechowych. U około połowy pacjentów z dyskinezją rzęsek pierwotną występuje zaburzenie ułożenia narządów (sytus inwersyjny całkowity lub sytus niejednoznaczny/heterotaksja).",
            "management": null,
            "evidence": {
              "gencc": [
                "ClinGen",
                "G2P",
                "Labcorp Genetics (formerly Invitae)",
                "PanelApp Australia"
              ],
              "clingen": "Definitive",
              "acmgSf": false,
              "inheritance": [
                "autosomal-dominant"
              ],
              "actionability": 10
            },
            "sameAsReport": true,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/pl/conditions/primary-ciliary-dyskinesia"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abdominal-situs-inversus",
        "name": "Abdominal situs inversus",
        "systems": [
          "abnormality-of-the-digestive-system",
          "growth-abnormality"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abdominal-situs-inversus"
      },
      {
        "slug": "abnormal-cardiovascular-system-morphology",
        "name": "Abnormal cardiovascular system morphology",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-cardiovascular-system-morphology"
      },
      {
        "slug": "abnormal-inferior-vena-cava-morphology",
        "name": "Abnormal inferior vena cava morphology",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/abnormal-inferior-vena-cava-morphology"
      },
      {
        "slug": "abnormal-atrial-arrangement",
        "name": "Abnormal location of heart atrium",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/abnormal-atrial-arrangement"
      },
      {
        "slug": "abnormal-sperm-motility",
        "name": "Abnormal sperm motility",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-sperm-motility"
      },
      {
        "slug": "abnormal-sputum",
        "name": "Abnormal sputum",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-sputum"
      },
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "systems": [],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      },
      {
        "slug": "abnormal-heart-morphology",
        "name": "Abnormality of the heart",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-heart-morphology"
      },
      {
        "slug": "abnormality-of-the-skeletal-system",
        "name": "Abnormality of the skeletal system",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormality-of-the-skeletal-system"
      },
      {
        "slug": "asplenia",
        "name": "Absent spleen",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-digestive-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/asplenia"
      },
      {
        "slug": "situs-inversus-totalis",
        "name": "All organs on wrong side of body",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/situs-inversus-totalis"
      },
      {
        "slug": "anomalous-pulmonary-venous-return",
        "name": "Anomalous pulmonary venous return",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/anomalous-pulmonary-venous-return"
      },
      {
        "slug": "atrial-situs-ambiguous",
        "name": "Atrial situs ambiguous",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/atrial-situs-ambiguous"
      },
      {
        "slug": "nasal-congestion",
        "name": "Blockage of nose",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/nasal-congestion"
      },
      {
        "slug": "chronic-otitis-media",
        "name": "Chronic infections of the middle ear",
        "systems": [
          "abnormality-of-the-ear",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/chronic-otitis-media"
      },
      {
        "slug": "chronic-rhinitis",
        "name": "Chronic rhinitis",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/chronic-rhinitis"
      },
      {
        "slug": "chronic-sinusitis",
        "name": "Chronic sinus disease",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-immune-system",
          "abnormality-of-the-musculoskeletal-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/chronic-sinusitis"
      },
      {
        "slug": "clubbing",
        "name": "Clubbing of fingers and toes",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/clubbing"
      },
      {
        "slug": "conductive-hearing-impairment",
        "name": "Conductive deafness",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/conductive-hearing-impairment"
      },
      {
        "slug": "delayed-speech-and-language-development",
        "name": "Delayed speech and language development",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/delayed-speech-and-language-development"
      },
      {
        "slug": "double-outlet-right-ventricle",
        "name": "Double outlet right ventricle",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/double-outlet-right-ventricle"
      },
      {
        "slug": "female-infertility",
        "name": "Female infertility",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/female-infertility"
      },
      {
        "slug": "hearing-impairment",
        "name": "Hearing impairment",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/hearing-impairment"
      },
      {
        "slug": "intestinal-malrotation",
        "name": "Intestinal malrotation",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/intestinal-malrotation"
      },
      {
        "slug": "lithoptysis",
        "name": "Lithoptysis",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/lithoptysis"
      },
      {
        "slug": "male-infertility",
        "name": "Male infertility",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/male-infertility"
      },
      {
        "slug": "morphological-central-nervous-system-abnormality",
        "name": "Morphological central nervous system abnormality",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/morphological-central-nervous-system-abnormality"
      },
      {
        "slug": "polysplenia",
        "name": "Multiple small spleens",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-digestive-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/polysplenia"
      },
      {
        "slug": "nasal-polyposis",
        "name": "Nasal polyposis",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/nasal-polyposis"
      },
      {
        "slug": "neonatal-respiratory-distress",
        "name": "Neonatal respiratory distress",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/neonatal-respiratory-distress"
      },
      {
        "slug": "noncommunicating-hydrocephalus",
        "name": "Noncommunicating hydrocephalus",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/noncommunicating-hydrocephalus"
      },
      {
        "slug": "airway-obstruction",
        "name": "Obstructive lung disease",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/airway-obstruction"
      },
      {
        "slug": "atelectasis",
        "name": "Partial or complete collapse of part or entire lung",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/atelectasis"
      },
      {
        "slug": "peribronchovascular-interstitial-thickening",
        "name": "Peribronchovascular interstitial thickening",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/peribronchovascular-interstitial-thickening"
      },
      {
        "slug": "bronchiectasis",
        "name": "Permanent enlargement of the airways of the lungs",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/bronchiectasis"
      },
      {
        "slug": "persistent-left-superior-vena-cava",
        "name": "Persistent left superior vena cava",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/persistent-left-superior-vena-cava"
      },
      {
        "slug": "pulmonary-situs-ambiguus",
        "name": "Pulmonary situs ambiguus",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/pulmonary-situs-ambiguus"
      },
      {
        "slug": "recurrent-lower-respiratory-tract-infections",
        "name": "Recurrent chest infections",
        "systems": [
          "abnormality-of-the-immune-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/recurrent-lower-respiratory-tract-infections"
      },
      {
        "slug": "recurrent-upper-respiratory-tract-infections",
        "name": "Recurrent colds",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-immune-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/recurrent-upper-respiratory-tract-infections"
      },
      {
        "slug": "recurrent-otitis-media",
        "name": "Recurrent middle ear infection",
        "systems": [
          "abnormality-of-the-ear",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/recurrent-otitis-media"
      },
      {
        "slug": "recurrent-mycobacterial-infections",
        "name": "Recurrent mycobacterial infections",
        "systems": [
          "abnormality-of-the-immune-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/recurrent-mycobacterial-infections"
      },
      {
        "slug": "recurrent-sinopulmonary-infections",
        "name": "Recurrent sinus and lung infections",
        "systems": [
          "abnormality-of-the-immune-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/recurrent-sinopulmonary-infections"
      },
      {
        "slug": "respiratory-failure",
        "name": "Respiratory failure",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/respiratory-failure"
      },
      {
        "slug": "respiratory-tract-infection",
        "name": "Respiratory tract infection",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/respiratory-tract-infection"
      },
      {
        "slug": "rod-cone-dystrophy",
        "name": "Rod-cone dystrophy",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/rod-cone-dystrophy"
      },
      {
        "slug": "hydrocephalus",
        "name": "Too much cerebrospinal fluid in the brain",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/hydrocephalus"
      },
      {
        "slug": "transposition-of-the-great-arteries",
        "name": "Transposition of the great arteries",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/transposition-of-the-great-arteries"
      },
      {
        "slug": "ventriculomegaly",
        "name": "Ventriculomegaly",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/ventriculomegaly"
      },
      {
        "slug": "productive-cough",
        "name": "Wet cough",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/productive-cough"
      },
      {
        "slug": "wheezing",
        "name": "Wheezing",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/wheezing"
      }
    ],
    "related": [
      {
        "slug": "ccdc39",
        "symbol": "CCDC39",
        "name": "coiled-coil domain 39 molecular ruler complex subunit",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/ccdc39"
      },
      {
        "slug": "ccdc40",
        "symbol": "CCDC40",
        "name": "coiled-coil domain 40 molecular ruler complex subunit",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/ccdc40"
      },
      {
        "slug": "ccno",
        "symbol": "CCNO",
        "name": "cyclin O",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/ccno"
      },
      {
        "slug": "cenpf",
        "symbol": "CENPF",
        "name": "centromere protein F",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/cenpf"
      },
      {
        "slug": "cfap20dc",
        "symbol": "CFAP20DC",
        "name": "CFAP20 domain containing",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/cfap20dc"
      },
      {
        "slug": "cfap221",
        "symbol": "CFAP221",
        "name": "cilia and flagella associated protein 221",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/cfap221"
      },
      {
        "slug": "cfap298",
        "symbol": "CFAP298",
        "name": "cilia and flagella associated protein 298",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/cfap298"
      },
      {
        "slug": "cfap300",
        "symbol": "CFAP300",
        "name": "cilia and flagella associated protein 300",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/cfap300"
      },
      {
        "slug": "cfap54",
        "symbol": "CFAP54",
        "name": "cilia and flagella associated protein 54",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/cfap54"
      },
      {
        "slug": "clxn",
        "symbol": "CLXN",
        "name": "calaxin",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/clxn"
      },
      {
        "slug": "daw1",
        "symbol": "DAW1",
        "name": "dynein assembly factor with WD repeats 1",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/daw1"
      },
      {
        "slug": "dnaaf1",
        "symbol": "DNAAF1",
        "name": "dynein axonemal assembly factor 1",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/dnaaf1"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}