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    "reports": [
      {
        "slug": "congenital-adrenal-hyperplasia",
        "name": "Wrodzony przerost nadnerczy",
        "diseases": [
          {
            "mondoId": "MONDO:0018479",
            "name": "Wrodzony przerost nadnerczy",
            "genes": 6,
            "inheritance": "autosomal-recessive",
            "description": "Wrodzony przerost nadnerczy (CAH) to dziedziczne zaburzenie endokrynologiczne spowodowane niedoborem enzymu steroidogenezy. Charakteryzuje się niewydolnością nadnerczy oraz różnym stopniem objawów nadmiaru lub niedoboru androgenów, zależnie od typu i ciężkości choroby.",
            "management": "Terapia zastępcza glikokortykoidami (hydrokortyzon u dzieci; prednizon lub deksametazon u dorosłych); terapia zastępcza mineralokortykoidami w przypadku utraty soli (fludrokortyzon); adrenalektomia w ciężkim hiperandrogenizmie opornym na leczenie farmakologiczne; protokoły dawkowania leków w sytuacjach stresowych",
            "evidence": {
              "gencc": [
                "Labcorp Genetics (formerly Invitae)",
                "Laboratory for Molecular Medicine",
                "Myriad Women's Health"
              ],
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ],
              "actionability": 7
            },
            "sameAsReport": true,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/pl/conditions/congenital-adrenal-hyperplasia"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormal-thorax-morphology",
        "name": "Abnormality of the chest",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/abnormal-thorax-morphology"
      },
      {
        "slug": "adrenogenital-syndrome",
        "name": "Adrenogenital syndrome",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "url": "https://dantelabs.com/traits/adrenogenital-syndrome"
      },
      {
        "slug": "elevated-circulating-21-deoxycortisol-concentration",
        "name": "Elevated circulating 21-deoxycortisol concentration",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "url": "https://dantelabs.com/traits/elevated-circulating-21-deoxycortisol-concentration"
      },
      {
        "slug": "adrenal-hyperplasia",
        "name": "Enlarged adrenal glands",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "url": "https://dantelabs.com/traits/adrenal-hyperplasia"
      },
      {
        "slug": "gynecomastia",
        "name": "Enlarged male breast",
        "systems": [
          "abnormality-of-the-breast"
        ],
        "url": "https://dantelabs.com/traits/gynecomastia"
      },
      {
        "slug": "recurrent-fever",
        "name": "Episodic fever",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "url": "https://dantelabs.com/traits/recurrent-fever"
      },
      {
        "slug": "fever",
        "name": "Fever",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "url": "https://dantelabs.com/traits/fever"
      },
      {
        "slug": "growth-abnormality",
        "name": "Growth abnormality",
        "systems": [],
        "url": "https://dantelabs.com/traits/growth-abnormality"
      },
      {
        "slug": "hypertension",
        "name": "High blood pressure",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "url": "https://dantelabs.com/traits/hypertension"
      },
      {
        "slug": "hypospadias",
        "name": "Hypospadias",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "url": "https://dantelabs.com/traits/hypospadias"
      },
      {
        "slug": "renal-salt-wasting",
        "name": "Loss of salt in urine",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "url": "https://dantelabs.com/traits/renal-salt-wasting"
      },
      {
        "slug": "hypoglycemia",
        "name": "Low blood sugar",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "url": "https://dantelabs.com/traits/hypoglycemia"
      }
    ],
    "related": [
      {
        "slug": "cyp11b1",
        "symbol": "CYP11B1",
        "name": "cytochrome P450 family 11 subfamily B member 1",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/cyp11b1"
      },
      {
        "slug": "cyp17a1",
        "symbol": "CYP17A1",
        "name": "cytochrome P450 family 17 subfamily A member 1",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/cyp17a1"
      },
      {
        "slug": "hsd3b2",
        "symbol": "HSD3B2",
        "name": "hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/hsd3b2"
      },
      {
        "slug": "por",
        "symbol": "POR",
        "name": "cytochrome p450 oxidoreductase",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/por"
      },
      {
        "slug": "star",
        "symbol": "STAR",
        "name": "steroidogenic acute regulatory protein",
        "shared": 1,
        "url": "https://dantelabs.com/pl/genes/star"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}