{
  "url": "https://dantelabs.com/traits/reduced-delayed-hypersensitivity",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "reduced-delayed-hypersensitivity",
    "id": "HP:0002972",
    "name": "Reduced delayed hypersensitivity",
    "definition": "Decreased ability to react to a delayed hypersensitivity skin test.",
    "synonyms": [
      "Decreased reactivity to skin test antigens",
      "Deficiency of delayed skin hypersensitivity",
      "Impaired delayed hypersensitivity"
    ],
    "systems": [
      {
        "slug": "abnormal-cellular-phenotype",
        "name": "Abnormal cellular phenotype",
        "url": "https://dantelabs.com/traits/abnormal-cellular-phenotype"
      },
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      },
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-delayed-hypersensitivity-skin-test",
        "name": "Abnormal delayed hypersensitivity skin test",
        "url": "https://dantelabs.com/traits/abnormal-delayed-hypersensitivity-skin-test"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "nsmce3",
        "symbol": "NSMCE3",
        "hgnc": "HGNC:7677",
        "name": "NSE3 component of SMC5/6 complex",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nsmce3"
      },
      {
        "slug": "casp10",
        "symbol": "CASP10",
        "hgnc": "HGNC:1500",
        "name": "caspase 10",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/casp10"
      },
      {
        "slug": "fas",
        "symbol": "FAS",
        "hgnc": "HGNC:11920",
        "name": "Fas cell surface death receptor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fas"
      },
      {
        "slug": "faslg",
        "symbol": "FASLG",
        "hgnc": "HGNC:11936",
        "name": "Fas ligand",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/faslg"
      },
      {
        "slug": "foxn1",
        "symbol": "FOXN1",
        "hgnc": "HGNC:12765",
        "name": "forkhead box N1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/foxn1"
      },
      {
        "slug": "rab27a",
        "symbol": "RAB27A",
        "hgnc": "HGNC:9766",
        "name": "RAB27A, member RAS oncogene family",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab27a"
      }
    ]
  }
}