{
  "url": "https://dantelabs.com/traits/hypoprolinemia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hypoprolinemia",
    "id": "HP:0500139",
    "name": "Decreased blood proline levels",
    "label": "Hypoprolinemia",
    "definition": "The concentration of proline in the blood circulation is below the lower limit of normal.",
    "synonyms": [
      "Low blood proline concentration",
      "Decreased proline concentration",
      "Decreased proline level",
      "Decreased proline level in blood",
      "Reduced proline concentration",
      "Reduced proline level",
      "Reduced proline level in blood"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-proline-concentration",
        "name": "Abnormal circulating proline concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-proline-concentration"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "aldh18a1",
        "symbol": "ALDH18A1",
        "hgnc": "HGNC:9722",
        "name": "aldehyde dehydrogenase 18 family member A1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aldh18a1"
      }
    ]
  }
}