{
  "url": "https://dantelabs.com/traits/cutaneous-abscess",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "cutaneous-abscess",
    "id": "HP:0031292",
    "name": "Skin abscess",
    "label": "Cutaneous abscess",
    "definition": "A circumscribed area of pus or necrotic debris in the skin (within the epidermis or dermis).",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      },
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "abscess",
        "name": "Abscess",
        "url": "https://dantelabs.com/traits/abscess"
      },
      {
        "slug": "inflammatory-abnormality-of-the-skin",
        "name": "Inflammatory abnormality of the skin",
        "url": "https://dantelabs.com/traits/inflammatory-abnormality-of-the-skin"
      }
    ],
    "narrower": [
      {
        "slug": "perianal-abscess",
        "name": "Perianal abscess",
        "genes": 13,
        "url": "https://dantelabs.com/traits/perianal-abscess"
      },
      {
        "slug": "recurrent-cutaneous-abscess-formation",
        "name": "Recurrent cutaneous abscess formation",
        "genes": 12,
        "url": "https://dantelabs.com/traits/recurrent-cutaneous-abscess-formation"
      }
    ],
    "genes": [
      {
        "slug": "il17ra",
        "symbol": "IL17RA",
        "hgnc": "HGNC:5985",
        "name": "interleukin 17 receptor A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/il17ra"
      },
      {
        "slug": "mpeg1",
        "symbol": "MPEG1",
        "hgnc": "HGNC:29619",
        "name": "macrophage expressed 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mpeg1"
      },
      {
        "slug": "dock8",
        "symbol": "DOCK8",
        "hgnc": "HGNC:19191",
        "name": "dedicator of cytokinesis 8",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dock8"
      },
      {
        "slug": "pgm3",
        "symbol": "PGM3",
        "hgnc": "HGNC:8907",
        "name": "phosphoglucomutase 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pgm3"
      },
      {
        "slug": "stat3",
        "symbol": "STAT3",
        "hgnc": "HGNC:11364",
        "name": "signal transducer and activator of transcription 3",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/stat3"
      },
      {
        "slug": "dclre1c",
        "symbol": "DCLRE1C",
        "hgnc": "HGNC:17642",
        "name": "DNA cross-link repair 1C",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dclre1c"
      },
      {
        "slug": "ikbkb",
        "symbol": "IKBKB",
        "hgnc": "HGNC:5960",
        "name": "inhibitor of nuclear factor kappa B kinase subunit beta",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ikbkb"
      },
      {
        "slug": "il6st",
        "symbol": "IL6ST",
        "hgnc": "HGNC:6021",
        "name": "interleukin 6 cytokine family signal transducer",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/il6st"
      },
      {
        "slug": "carmil2",
        "symbol": "CARMIL2",
        "hgnc": "HGNC:27089",
        "name": "capping protein regulator and myosin 1 linker 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/carmil2"
      },
      {
        "slug": "xiap",
        "symbol": "XIAP",
        "hgnc": "HGNC:592",
        "name": "X-linked inhibitor of apoptosis",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/xiap"
      },
      {
        "slug": "znf341",
        "symbol": "ZNF341",
        "hgnc": "HGNC:15992",
        "name": "zinc finger protein 341",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znf341"
      },
      {
        "slug": "il6r",
        "symbol": "IL6R",
        "hgnc": "HGNC:6019",
        "name": "interleukin 6 receptor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/il6r"
      },
      {
        "slug": "otulin",
        "symbol": "OTULIN",
        "hgnc": "HGNC:25118",
        "name": "OTU deubiquitinase with linear linkage specificity",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/otulin"
      }
    ]
  }
}