{
  "url": "https://dantelabs.com/traits/abnormal-hand-bone-ossification",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-hand-bone-ossification",
    "id": "HP:0010660",
    "name": "Abnormal maturation of the hand bones",
    "label": "Abnormal hand bone ossification",
    "definition": "An abnormality of the formation and mineralization of any bone of the skeleton of hand.",
    "synonyms": [
      "Abnormal ossification of hand bones",
      "Abnormality of the mineralisation and ossification of bones of the hand"
    ],
    "systems": [
      {
        "slug": "abnormality-of-limbs",
        "name": "Abnormality of limbs",
        "url": "https://dantelabs.com/traits/abnormality-of-limbs"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-enchondral-ossification",
        "name": "Abnormal enchondral ossification",
        "url": "https://dantelabs.com/traits/abnormal-enchondral-ossification"
      },
      {
        "slug": "abnormal-hand-morphology",
        "name": "Abnormal shape of hand",
        "url": "https://dantelabs.com/traits/abnormal-hand-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "irregular-ossification-of-hand-bones",
        "name": "Irregular maturation of hand bones",
        "genes": 1,
        "url": "https://dantelabs.com/traits/irregular-ossification-of-hand-bones"
      },
      {
        "slug": "abnormality-of-carpal-bone-ossification",
        "name": "Abnormal wrist bone maturation",
        "genes": 0,
        "url": "https://dantelabs.com/traits/abnormality-of-carpal-bone-ossification"
      },
      {
        "slug": "epiphyseal-stippling-of-finger-phalanges",
        "name": "Speckled calcifications in end part of finger bones",
        "genes": 0,
        "url": "https://dantelabs.com/traits/epiphyseal-stippling-of-finger-phalanges"
      }
    ],
    "genes": [
      {
        "slug": "flna",
        "symbol": "FLNA",
        "hgnc": "HGNC:3754",
        "name": "filamin A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flna"
      },
      {
        "slug": "trip11",
        "symbol": "TRIP11",
        "hgnc": "HGNC:12305",
        "name": "thyroid hormone receptor interactor 11",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trip11"
      }
    ]
  }
}