{
  "url": "https://dantelabs.com/traits/2-hydroxyadipic-aciduria",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "2-hydroxyadipic-aciduria",
    "id": "HP:0034465",
    "name": "2-hydroxyadipic aciduria",
    "definition": "The concentration of 2-hydroxyadipic acid in the urine, normalized for urine concentration, is above the upper limit of normal.",
    "synonyms": [
      "2-hydroxyadipic acid high in urine"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "elevated-urinary-dicarboxylic-acid-level",
        "name": "Elevated urinary dicarboxylic acid level",
        "url": "https://dantelabs.com/traits/elevated-urinary-dicarboxylic-acid-level"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "dhtkd1",
        "symbol": "DHTKD1",
        "hgnc": "HGNC:23537",
        "name": "dehydrogenase E1 and transketolase domain containing 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dhtkd1"
      }
    ]
  }
}