{
  "url": "https://dantelabs.com/no/genes/vim",
  "gene": {
    "slug": "vim",
    "symbol": "VIM",
    "name": "vimentin",
    "hgnc": "HGNC:12692",
    "summary": null,
    "location": "10p13",
    "locusType": "gene with protein product",
    "aliases": [],
    "previousSymbols": [],
    "ensemblId": "ENSG00000026025",
    "entrezId": 7431,
    "omim": [
      "193060"
    ],
    "uniprot": [
      "P08670"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "10",
      "start": 17228241,
      "end": 17237593,
      "strand": "+",
      "ensemblTranscript": "ENST00000544301.7",
      "refseqTranscript": "NM_003380.5",
      "ensemblProtein": "ENSP00000446007.1",
      "refseqProtein": "NP_003371.2",
      "exons": [
        {
          "start": 17228241,
          "end": 17228524
        },
        {
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        {
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        {
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        {
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        },
        {
          "start": 17234693,
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        },
        {
          "start": 17235169,
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        {
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        {
          "start": 17236294,
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        },
        {
          "start": 17237230,
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        }
      ],
      "cds": {
        "start": 17229423,
        "end": 17237271
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "10",
      "start": 17270258,
      "end": 17279592,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 16732917,
      "end": 17732916,
      "genes": [
        {
          "symbol": "RSU1",
          "ensemblId": "ENSG00000148484",
          "biotype": "protein_coding",
          "start": 16567276,
          "end": 16817603,
          "strand": "-",
          "slug": "rsu1"
        },
        {
          "symbol": "CUBN",
          "ensemblId": "ENSG00000107611",
          "biotype": "protein_coding",
          "start": 16823966,
          "end": 17129970,
          "strand": "-",
          "slug": "cubn"
        },
        {
          "symbol": "TRDMT1",
          "ensemblId": "ENSG00000107614",
          "biotype": "protein_coding",
          "start": 17137336,
          "end": 17202054,
          "strand": "-",
          "slug": "trdmt1"
        },
        {
          "symbol": "ST8SIA6",
          "ensemblId": "ENSG00000148488",
          "biotype": "protein_coding",
          "start": 17315416,
          "end": 17454681,
          "strand": "-",
          "slug": "st8sia6"
        },
        {
          "symbol": "HACD1",
          "ensemblId": "ENSG00000165996",
          "biotype": "protein_coding",
          "start": 17588301,
          "end": 17617566,
          "strand": "-",
          "slug": "hacd1"
        },
        {
          "symbol": "STAM",
          "ensemblId": "ENSG00000136738",
          "biotype": "protein_coding",
          "start": 17644124,
          "end": 17735901,
          "strand": "+",
          "slug": "stam"
        }
      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "hereditary-congenital-and-juvenile-cataract",
        "name": "Arvelig medfødt og juvenil katarakt",
        "diseases": [
          {
            "mondoId": "MONDO:0011060",
            "name": "Ikke-syndromisk katarakt med tidlig debut",
            "genes": 22,
            "inheritance": null,
            "description": "Katarakt som oppstår ved fødselen eller tidlig i livet uten andre trekk, forårsaket av endringer i linsegener som krystallinene (CRYAA, CRYBB2, CRYGD og andre), GJA3, GJA8 og MIP.",
            "management": "Tidlig oppdagelse og operasjon hos barn bidrar til å forhindre varig synstap på grunn av amblyopi, og familiemedlemmer kan tilbys øyekontroller.",
            "evidence": {
              "gencc": [
                "Labcorp Genetics (formerly Invitae)",
                "PanelApp Australia"
              ],
              "acmgSf": false,
              "inheritance": [
                "autosomal-dominant"
              ]
            },
            "sameAsReport": false,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/no/conditions/hereditary-congenital-and-juvenile-cataract"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "diffuse-nuclear-cataract",
        "name": "Diffuse nuclear cataract",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/diffuse-nuclear-cataract"
      },
      {
        "slug": "posterior-polar-cataract",
        "name": "Posterior polar cataract",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/posterior-polar-cataract"
      },
      {
        "slug": "pulverulent-cataract",
        "name": "Pulverulent cataract",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/pulverulent-cataract"
      }
    ],
    "related": [
      {
        "slug": "bfsp1",
        "symbol": "BFSP1",
        "name": "beaded filament structural protein 1",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/bfsp1"
      },
      {
        "slug": "chmp4b",
        "symbol": "CHMP4B",
        "name": "charged multivesicular body protein 4B",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/chmp4b"
      },
      {
        "slug": "cryab",
        "symbol": "CRYAB",
        "name": "crystallin alpha B",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cryab"
      },
      {
        "slug": "cryba1",
        "symbol": "CRYBA1",
        "name": "crystallin beta A1",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cryba1"
      },
      {
        "slug": "cryba2",
        "symbol": "CRYBA2",
        "name": "crystallin beta A2",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cryba2"
      },
      {
        "slug": "cryba4",
        "symbol": "CRYBA4",
        "name": "crystallin beta A4",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cryba4"
      },
      {
        "slug": "crybb1",
        "symbol": "CRYBB1",
        "name": "crystallin beta B1",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/crybb1"
      },
      {
        "slug": "crybb3",
        "symbol": "CRYBB3",
        "name": "crystallin beta B3",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/crybb3"
      },
      {
        "slug": "crygs",
        "symbol": "CRYGS",
        "name": "crystallin gamma S",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/crygs"
      },
      {
        "slug": "epha2",
        "symbol": "EPHA2",
        "name": "EPH receptor A2",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/epha2"
      },
      {
        "slug": "gcnt2",
        "symbol": "GCNT2",
        "name": "glucosaminyl (N-acetyl) transferase 2 (I blood group)",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/gcnt2"
      },
      {
        "slug": "gja3",
        "symbol": "GJA3",
        "name": "gap junction protein alpha 3",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/gja3"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}