{
  "url": "https://dantelabs.com/no/genes/tmem132e",
  "gene": {
    "slug": "tmem132e",
    "symbol": "TMEM132E",
    "name": "transmembrane protein 132E",
    "hgnc": "HGNC:26991",
    "summary": null,
    "location": "17q12",
    "locusType": "gene with protein product",
    "aliases": [
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    "previousSymbols": [],
    "ensemblId": "ENSG00000181291",
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      "refseqProtein": "NP_001291367.1",
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        {
          "symbol": "ASIC2",
          "ensemblId": "ENSG00000108684",
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        {
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          "ensemblId": "ENSG00000108688",
          "biotype": "protein_coding",
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        {
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          "biotype": "protein_coding",
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          "strand": "+",
          "slug": "ccl8"
        },
        {
          "symbol": "CCL13",
          "ensemblId": "ENSG00000181374",
          "biotype": "protein_coding",
          "start": 34356438,
          "end": 34358610,
          "strand": "+",
          "slug": "ccl13"
        },
        {
          "symbol": "CCL1",
          "ensemblId": "ENSG00000108702",
          "biotype": "protein_coding",
          "start": 34360328,
          "end": 34363233,
          "strand": "-",
          "slug": "ccl1"
        },
        {
          "symbol": "CCT6B",
          "ensemblId": "ENSG00000132141",
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          "end": 34981078,
          "strand": "-",
          "slug": "cct6b"
        },
        {
          "symbol": "ZNF830",
          "ensemblId": "ENSG00000198783",
          "biotype": "protein_coding",
          "start": 34961540,
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          "strand": "+",
          "slug": "znf830"
        },
        {
          "symbol": "LIG3",
          "ensemblId": "ENSG00000005156",
          "biotype": "protein_coding",
          "start": 34980462,
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          "strand": "+",
          "slug": "lig3"
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        {
          "symbol": "RFFL",
          "ensemblId": "ENSG00000092871",
          "biotype": "protein_coding",
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          "strand": "-",
          "slug": "rffl"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000267618",
          "biotype": "protein_coding",
          "start": 35011349,
          "end": 35121493,
          "strand": "-"
        },
        {
          "symbol": "RAD51D",
          "ensemblId": "ENSG00000185379",
          "biotype": "protein_coding",
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          "end": 35121522,
          "strand": "-",
          "slug": "rad51d"
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      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "hearing-loss-and-deafness",
        "name": "Hørselstap og døvhet",
        "diseases": [
          {
            "mondoId": "MONDO:0019497",
            "name": "Ikke-syndromisk genetisk hørselstap",
            "genes": 97,
            "inheritance": null,
            "description": "Arvelig hørselstap uten andre medisinske trekk, inkludert de vanlige recessive formene forårsaket av GJB2, OTOF, SLC26A4, STRC og mange andre gener, samt dominante, X-bundne og mitokondrielle former.",
            "management": "Kunnskap om den genetiske årsaken kan veilede valg av hørselshjelpemidler og cochleaimplantat, vurdering av om du kan delta i genterapistudier (for eksempel OTOF), og familieveiledning.",
            "evidence": {
              "gencc": [
                "Labcorp Genetics (formerly Invitae)"
              ],
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ]
            },
            "sameAsReport": false,
            "broad": true
          }
        ],
        "url": "https://dantelabs.com/no/conditions/hearing-loss-and-deafness"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormal-vestibular-function",
        "name": "Abnormal vestibular function",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/abnormal-vestibular-function"
      },
      {
        "slug": "sensorineural-hearing-impairment",
        "name": "Sensorineural hearing impairment",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/sensorineural-hearing-impairment"
      }
    ],
    "related": [
      {
        "slug": "actg1",
        "symbol": "ACTG1",
        "name": "actin gamma 1",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/actg1"
      },
      {
        "slug": "afg2b",
        "symbol": "AFG2B",
        "name": "AAA ATPase AFG2B",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/afg2b"
      },
      {
        "slug": "aifm1",
        "symbol": "AIFM1",
        "name": "apoptosis inducing factor mitochondria associated 1",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/aifm1"
      },
      {
        "slug": "atp11a",
        "symbol": "ATP11A",
        "name": "ATPase phospholipid transporting 11A",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/atp11a"
      },
      {
        "slug": "atp2b2",
        "symbol": "ATP2B2",
        "name": "ATPase plasma membrane Ca2+ transporting 2",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/atp2b2"
      },
      {
        "slug": "cabp2",
        "symbol": "CABP2",
        "name": "calcium binding protein 2",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cabp2"
      },
      {
        "slug": "cd164",
        "symbol": "CD164",
        "name": "CD164 molecule",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cd164"
      },
      {
        "slug": "cdc14a",
        "symbol": "CDC14A",
        "name": "cell division cycle 14A",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cdc14a"
      },
      {
        "slug": "cdh23",
        "symbol": "CDH23",
        "name": "cadherin related 23",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cdh23"
      },
      {
        "slug": "ceacam16",
        "symbol": "CEACAM16",
        "name": "CEA cell adhesion molecule 16, tectorial membrane component",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/ceacam16"
      },
      {
        "slug": "cib2",
        "symbol": "CIB2",
        "name": "calcium and integrin binding family member 2",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cib2"
      },
      {
        "slug": "cldn14",
        "symbol": "CLDN14",
        "name": "claudin 14",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cldn14"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}