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  "url": "https://dantelabs.com/no/genes/ptprq",
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          "symbol": "OTOGL",
          "ensemblId": "ENSG00000165899",
          "biotype": "protein_coding",
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        "name": "Hørselstap og døvhet",
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            "name": "Autosomal dominant ikke-syndromisk hørselstap",
            "genes": 39,
            "inheritance": "autosomal-dominant",
            "description": "Autosomal dominant form for ikke-syndromisk døvhet.",
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              "inheritance": [
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            "name": "Ikke-syndromisk genetisk hørselstap",
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            "inheritance": null,
            "description": "Arvelig hørselstap uten andre medisinske trekk, inkludert de vanlige recessive formene forårsaket av GJB2, OTOF, SLC26A4, STRC og mange andre gener, samt dominante, X-bundne og mitokondrielle former.",
            "management": "Kunnskap om den genetiske årsaken kan veilede valg av hørselshjelpemidler og cochleaimplantat, vurdering av om du kan delta i genterapistudier (for eksempel OTOF), og familieveiledning.",
            "evidence": {
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              "clingen": "Definitive",
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              "actionability": 10
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        "url": "https://dantelabs.com/no/conditions/hearing-loss-and-deafness"
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    ],
    "pharmacogenomics": [],
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        "slug": "abnormal-vestibular-function",
        "name": "Abnormal vestibular function",
        "systems": [
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        "url": "https://dantelabs.com/traits/abnormal-vestibular-function"
      },
      {
        "slug": "hearing-impairment",
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        "url": "https://dantelabs.com/traits/hearing-impairment"
      },
      {
        "slug": "motor-delay",
        "name": "Motor delay",
        "systems": [
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        "url": "https://dantelabs.com/traits/motor-delay"
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      {
        "slug": "sensorineural-hearing-impairment",
        "name": "Sensorineural hearing impairment",
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        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/sensorineural-hearing-impairment"
      }
    ],
    "related": [
      {
        "slug": "actg1",
        "symbol": "ACTG1",
        "name": "actin gamma 1",
        "shared": 2,
        "url": "https://dantelabs.com/no/genes/actg1"
      },
      {
        "slug": "atp11a",
        "symbol": "ATP11A",
        "name": "ATPase phospholipid transporting 11A",
        "shared": 2,
        "url": "https://dantelabs.com/no/genes/atp11a"
      },
      {
        "slug": "atp2b2",
        "symbol": "ATP2B2",
        "name": "ATPase plasma membrane Ca2+ transporting 2",
        "shared": 2,
        "url": "https://dantelabs.com/no/genes/atp2b2"
      },
      {
        "slug": "cd164",
        "symbol": "CD164",
        "name": "CD164 molecule",
        "shared": 2,
        "url": "https://dantelabs.com/no/genes/cd164"
      },
      {
        "slug": "ceacam16",
        "symbol": "CEACAM16",
        "name": "CEA cell adhesion molecule 16, tectorial membrane component",
        "shared": 2,
        "url": "https://dantelabs.com/no/genes/ceacam16"
      },
      {
        "slug": "coch",
        "symbol": "COCH",
        "name": "cochlin",
        "shared": 2,
        "url": "https://dantelabs.com/no/genes/coch"
      },
      {
        "slug": "col11a1",
        "symbol": "COL11A1",
        "name": "collagen type XI alpha 1 chain",
        "shared": 2,
        "url": "https://dantelabs.com/no/genes/col11a1"
      },
      {
        "slug": "col11a2",
        "symbol": "COL11A2",
        "name": "collagen type XI alpha 2 chain",
        "shared": 2,
        "url": "https://dantelabs.com/no/genes/col11a2"
      },
      {
        "slug": "diaph1",
        "symbol": "DIAPH1",
        "name": "diaphanous related formin 1",
        "shared": 2,
        "url": "https://dantelabs.com/no/genes/diaph1"
      },
      {
        "slug": "eya4",
        "symbol": "EYA4",
        "name": "EYA transcriptional coactivator and phosphatase 4",
        "shared": 2,
        "url": "https://dantelabs.com/no/genes/eya4"
      },
      {
        "slug": "gjb2",
        "symbol": "GJB2",
        "name": "gap junction protein beta 2",
        "shared": 2,
        "url": "https://dantelabs.com/no/genes/gjb2"
      },
      {
        "slug": "gjb6",
        "symbol": "GJB6",
        "name": "gap junction protein beta 6",
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        "url": "https://dantelabs.com/no/genes/gjb6"
      }
    ],
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      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
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}