{
  "url": "https://dantelabs.com/no/genes/odad1",
  "gene": {
    "slug": "odad1",
    "symbol": "ODAD1",
    "name": "outer dynein arm docking complex subunit 1",
    "hgnc": "HGNC:26560",
    "summary": null,
    "location": "19q13.33",
    "locusType": "gene with protein product",
    "aliases": [
      "FLJ32926",
      "CILD20"
    ],
    "previousSymbols": [
      "CCDC114"
    ],
    "ensemblId": "ENSG00000105479",
    "entrezId": 93233,
    "omim": [
      "615038"
    ],
    "uniprot": [
      "Q96M63"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "19",
      "start": 48296462,
      "end": 48321971,
      "strand": "-",
      "ensemblTranscript": "ENST00000674294.1",
      "refseqTranscript": "NM_001364171.2",
      "ensemblProtein": "ENSP00000501363.1",
      "refseqProtein": "NP_001351100.1",
      "exons": [
        {
          "start": 48296462,
          "end": 48297518
        },
        {
          "start": 48297590,
          "end": 48297668
        },
        {
          "start": 48298000,
          "end": 48298097
        },
        {
          "start": 48298177,
          "end": 48298340
        },
        {
          "start": 48302694,
          "end": 48302862
        },
        {
          "start": 48303013,
          "end": 48303095
        },
        {
          "start": 48303650,
          "end": 48303784
        },
        {
          "start": 48303953,
          "end": 48304140
        },
        {
          "start": 48306256,
          "end": 48306323
        },
        {
          "start": 48311553,
          "end": 48311666
        },
        {
          "start": 48311994,
          "end": 48312116
        },
        {
          "start": 48318387,
          "end": 48318576
        },
        {
          "start": 48318713,
          "end": 48318812
        },
        {
          "start": 48320299,
          "end": 48320391
        },
        {
          "start": 48320772,
          "end": 48320811
        },
        {
          "start": 48321678,
          "end": 48321971
        }
      ],
      "cds": {
        "start": 48296976,
        "end": 48320368
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "19",
      "start": 48799714,
      "end": 48825151,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 47809217,
      "end": 48809216,
      "genes": [
        {
          "symbol": "TPRX1",
          "ensemblId": "ENSG00000178928",
          "biotype": "protein_coding",
          "start": 47801232,
          "end": 47819051,
          "strand": "-",
          "slug": "tprx1"
        },
        {
          "symbol": "CRX",
          "ensemblId": "ENSG00000105392",
          "biotype": "protein_coding",
          "start": 47819779,
          "end": 47843330,
          "strand": "+",
          "slug": "crx"
        },
        {
          "symbol": "TPRX2",
          "ensemblId": "ENSG00000259009",
          "biotype": "protein_coding",
          "start": 47859235,
          "end": 47861721,
          "strand": "+",
          "slug": "tprx2"
        },
        {
          "symbol": "SULT2A1",
          "ensemblId": "ENSG00000105398",
          "biotype": "protein_coding",
          "start": 47870327,
          "end": 47886479,
          "strand": "-",
          "slug": "sult2a1"
        },
        {
          "symbol": "BSPH1",
          "ensemblId": "ENSG00000188334",
          "biotype": "protein_coding",
          "start": 47968046,
          "end": 47992170,
          "strand": "-",
          "slug": "bsph1"
        },
        {
          "symbol": "ELSPBP1",
          "ensemblId": "ENSG00000169393",
          "biotype": "protein_coding",
          "start": 47994632,
          "end": 48025154,
          "strand": "+",
          "slug": "elspbp1"
        },
        {
          "symbol": "CABP5",
          "ensemblId": "ENSG00000105507",
          "biotype": "protein_coding",
          "start": 48029383,
          "end": 48044079,
          "strand": "-",
          "slug": "cabp5"
        },
        {
          "symbol": "PLA2G4C",
          "ensemblId": "ENSG00000105499",
          "biotype": "protein_coding",
          "start": 48047843,
          "end": 48111390,
          "strand": "-",
          "slug": "pla2g4c"
        },
        {
          "symbol": "LIG1",
          "ensemblId": "ENSG00000105486",
          "biotype": "protein_coding",
          "start": 48115444,
          "end": 48170654,
          "strand": "-",
          "slug": "lig1"
        },
        {
          "symbol": "ZSWIM9",
          "ensemblId": "ENSG00000185453",
          "biotype": "protein_coding",
          "start": 48170645,
          "end": 48197624,
          "strand": "+",
          "slug": "zswim9"
        },
        {
          "symbol": "CARD8",
          "ensemblId": "ENSG00000105483",
          "biotype": "protein_coding",
          "start": 48180770,
          "end": 48255976,
          "strand": "-",
          "slug": "card8"
        },
        {
          "symbol": "ZNF114",
          "ensemblId": "ENSG00000178150",
          "biotype": "protein_coding",
          "start": 48270041,
          "end": 48289292,
          "strand": "+",
          "slug": "znf114"
        },
        {
          "symbol": "EMP3",
          "ensemblId": "ENSG00000142227",
          "biotype": "protein_coding",
          "start": 48321310,
          "end": 48330560,
          "strand": "+",
          "slug": "emp3"
        },
        {
          "symbol": "TMEM143",
          "ensemblId": "ENSG00000161558",
          "biotype": "protein_coding",
          "start": 48329918,
          "end": 48364245,
          "strand": "-",
          "slug": "tmem143"
        },
        {
          "symbol": "SYNGR4",
          "ensemblId": "ENSG00000105467",
          "biotype": "protein_coding",
          "start": 48364260,
          "end": 48376377,
          "strand": "+",
          "slug": "syngr4"
        },
        {
          "symbol": "KDELR1",
          "ensemblId": "ENSG00000105438",
          "biotype": "protein_coding",
          "start": 48382558,
          "end": 48393837,
          "strand": "-",
          "slug": "kdelr1"
        },
        {
          "symbol": "GRIN2D",
          "ensemblId": "ENSG00000105464",
          "biotype": "protein_coding",
          "start": 48393668,
          "end": 48444931,
          "strand": "+",
          "slug": "grin2d"
        },
        {
          "symbol": "GRWD1",
          "ensemblId": "ENSG00000105447",
          "biotype": "protein_coding",
          "start": 48445512,
          "end": 48458382,
          "strand": "+",
          "slug": "grwd1"
        },
        {
          "symbol": "KCNJ14",
          "ensemblId": "ENSG00000182324",
          "biotype": "protein_coding",
          "start": 48454464,
          "end": 48466980,
          "strand": "+",
          "slug": "kcnj14"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000268465",
          "biotype": "protein_coding",
          "start": 48465837,
          "end": 48472431,
          "strand": "+"
        },
        {
          "symbol": "CYTH2",
          "ensemblId": "ENSG00000105443",
          "biotype": "protein_coding",
          "start": 48469203,
          "end": 48482314,
          "strand": "+",
          "slug": "cyth2"
        },
        {
          "symbol": "LMTK3",
          "ensemblId": "ENSG00000142235",
          "biotype": "protein_coding",
          "start": 48485271,
          "end": 48513935,
          "strand": "-",
          "slug": "lmtk3"
        },
        {
          "symbol": "SULT2B1",
          "ensemblId": "ENSG00000088002",
          "biotype": "protein_coding",
          "start": 48552140,
          "end": 48599425,
          "strand": "+",
          "slug": "sult2b1"
        },
        {
          "symbol": "SACK1E",
          "ensemblId": "ENSG00000105523",
          "biotype": "protein_coding",
          "start": 48599961,
          "end": 48615093,
          "strand": "-",
          "slug": "sack1e"
        },
        {
          "symbol": "SPACA4",
          "ensemblId": "ENSG00000177202",
          "biotype": "protein_coding",
          "start": 48606742,
          "end": 48607962,
          "strand": "+",
          "slug": "spaca4"
        },
        {
          "symbol": "RPL18",
          "ensemblId": "ENSG00000063177",
          "biotype": "protein_coding",
          "start": 48615284,
          "end": 48619213,
          "strand": "-",
          "slug": "rpl18"
        },
        {
          "symbol": "SPHK2",
          "ensemblId": "ENSG00000063176",
          "biotype": "protein_coding",
          "start": 48619291,
          "end": 48630717,
          "strand": "+",
          "slug": "sphk2"
        },
        {
          "symbol": "DBP",
          "ensemblId": "ENSG00000105516",
          "biotype": "protein_coding",
          "start": 48630030,
          "end": 48637695,
          "strand": "-",
          "slug": "dbp"
        },
        {
          "symbol": "CA11",
          "ensemblId": "ENSG00000063180",
          "biotype": "protein_coding",
          "start": 48637946,
          "end": 48646386,
          "strand": "-",
          "slug": "ca11"
        },
        {
          "symbol": "NTN5",
          "ensemblId": "ENSG00000142233",
          "biotype": "protein_coding",
          "start": 48661407,
          "end": 48673081,
          "strand": "-",
          "slug": "ntn5"
        },
        {
          "symbol": "FUT2",
          "ensemblId": "ENSG00000176920",
          "biotype": "protein_coding",
          "start": 48695953,
          "end": 48705951,
          "strand": "+",
          "slug": "fut2"
        },
        {
          "symbol": "MAMSTR",
          "ensemblId": "ENSG00000176909",
          "biotype": "protein_coding",
          "start": 48711737,
          "end": 48719966,
          "strand": "-",
          "slug": "mamstr"
        },
        {
          "symbol": "RASIP1",
          "ensemblId": "ENSG00000105538",
          "biotype": "protein_coding",
          "start": 48720571,
          "end": 48740616,
          "strand": "-",
          "slug": "rasip1"
        },
        {
          "symbol": "IZUMO1",
          "ensemblId": "ENSG00000182264",
          "biotype": "protein_coding",
          "start": 48740852,
          "end": 48746909,
          "strand": "-",
          "slug": "izumo1"
        },
        {
          "symbol": "FUT1",
          "ensemblId": "ENSG00000174951",
          "biotype": "protein_coding",
          "start": 48748011,
          "end": 48755390,
          "strand": "-",
          "slug": "fut1"
        },
        {
          "symbol": "FGF21",
          "ensemblId": "ENSG00000105550",
          "biotype": "protein_coding",
          "start": 48755524,
          "end": 48758333,
          "strand": "+",
          "slug": "fgf21"
        },
        {
          "symbol": "BCAT2",
          "ensemblId": "ENSG00000105552",
          "biotype": "protein_coding",
          "start": 48795061,
          "end": 48811066,
          "strand": "-",
          "slug": "bcat2"
        }
      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "primary-ciliary-dyskinesia",
        "name": "Primær ciliær dyskinesi",
        "diseases": [
          {
            "mondoId": "MONDO:0016575",
            "name": "Primær ciliær dyskinesi",
            "genes": 50,
            "inheritance": "autosomal-recessive",
            "description": "En sjelden, genetisk heterogen sykdom som først og fremst rammer luftveiene, og som kjennetegnes av kronisk sykdom i øvre og nedre luftveier. Omtrent halvparten av pasientene med primær ciliær dyskinesi har en lateralitetsdefekt i organene (situs inversus totalis eller situs ambiguus/heterotaksi).",
            "management": null,
            "evidence": {
              "gencc": [
                "ClinGen",
                "G2P",
                "Labcorp Genetics (formerly Invitae)"
              ],
              "clingen": "Definitive",
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ],
              "actionability": 10
            },
            "sameAsReport": true,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/no/conditions/primary-ciliary-dyskinesia"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormal-cardiovascular-system-morphology",
        "name": "Abnormal cardiovascular system morphology",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-cardiovascular-system-morphology"
      },
      {
        "slug": "abnormal-inferior-vena-cava-morphology",
        "name": "Abnormal inferior vena cava morphology",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/abnormal-inferior-vena-cava-morphology"
      },
      {
        "slug": "abnormal-atrial-arrangement",
        "name": "Abnormal location of heart atrium",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/abnormal-atrial-arrangement"
      },
      {
        "slug": "abnormal-sperm-motility",
        "name": "Abnormal sperm motility",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-sperm-motility"
      },
      {
        "slug": "abnormal-sputum",
        "name": "Abnormal sputum",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-sputum"
      },
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "systems": [],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      },
      {
        "slug": "abnormal-heart-morphology",
        "name": "Abnormality of the heart",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-heart-morphology"
      },
      {
        "slug": "abnormality-of-the-skeletal-system",
        "name": "Abnormality of the skeletal system",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormality-of-the-skeletal-system"
      },
      {
        "slug": "absent-outer-dynein-arms",
        "name": "Absent outer dynein arms",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/absent-outer-dynein-arms"
      },
      {
        "slug": "asplenia",
        "name": "Absent spleen",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-digestive-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/asplenia"
      },
      {
        "slug": "situs-inversus-totalis",
        "name": "All organs on wrong side of body",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/situs-inversus-totalis"
      },
      {
        "slug": "anomalous-pulmonary-venous-return",
        "name": "Anomalous pulmonary venous return",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/anomalous-pulmonary-venous-return"
      },
      {
        "slug": "atrial-situs-ambiguous",
        "name": "Atrial situs ambiguous",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/atrial-situs-ambiguous"
      },
      {
        "slug": "atrial-situs-inversus",
        "name": "Atrial situs inversus",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/atrial-situs-inversus"
      },
      {
        "slug": "nasal-congestion",
        "name": "Blockage of nose",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/nasal-congestion"
      },
      {
        "slug": "chronic-otitis-media",
        "name": "Chronic infections of the middle ear",
        "systems": [
          "abnormality-of-the-ear",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/chronic-otitis-media"
      },
      {
        "slug": "chronic-rhinitis",
        "name": "Chronic rhinitis",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/chronic-rhinitis"
      },
      {
        "slug": "chronic-sinusitis",
        "name": "Chronic sinus disease",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-immune-system",
          "abnormality-of-the-musculoskeletal-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/chronic-sinusitis"
      },
      {
        "slug": "ciliary-dyskinesia",
        "name": "Ciliary dyskinesia",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "url": "https://dantelabs.com/traits/ciliary-dyskinesia"
      },
      {
        "slug": "clubbing",
        "name": "Clubbing of fingers and toes",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/clubbing"
      },
      {
        "slug": "conductive-hearing-impairment",
        "name": "Conductive deafness",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/conductive-hearing-impairment"
      },
      {
        "slug": "hemoptysis",
        "name": "Coughing up blood",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hemoptysis"
      },
      {
        "slug": "delayed-speech-and-language-development",
        "name": "Delayed speech and language development",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/delayed-speech-and-language-development"
      },
      {
        "slug": "double-outlet-right-ventricle",
        "name": "Double outlet right ventricle",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/double-outlet-right-ventricle"
      },
      {
        "slug": "female-infertility",
        "name": "Female infertility",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/female-infertility"
      },
      {
        "slug": "hearing-impairment",
        "name": "Hearing impairment",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/hearing-impairment"
      },
      {
        "slug": "dextrocardia",
        "name": "Heart tip and four chambers point towards right side of body",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/dextrocardia"
      },
      {
        "slug": "ventricular-septal-defect",
        "name": "Hole in heart wall separating two lower heart chambers",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/ventricular-septal-defect"
      },
      {
        "slug": "pulmonary-arterial-hypertension",
        "name": "Increased blood pressure in blood vessels of lungs",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/pulmonary-arterial-hypertension"
      },
      {
        "slug": "intestinal-malrotation",
        "name": "Intestinal malrotation",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/intestinal-malrotation"
      },
      {
        "slug": "lithoptysis",
        "name": "Lithoptysis",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/lithoptysis"
      },
      {
        "slug": "male-infertility",
        "name": "Male infertility",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/male-infertility"
      },
      {
        "slug": "morphological-central-nervous-system-abnormality",
        "name": "Morphological central nervous system abnormality",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/morphological-central-nervous-system-abnormality"
      },
      {
        "slug": "polysplenia",
        "name": "Multiple small spleens",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-digestive-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/polysplenia"
      },
      {
        "slug": "aortic-valve-stenosis",
        "name": "Narrowing of aortic valve",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/aortic-valve-stenosis"
      },
      {
        "slug": "pulmonary-artery-stenosis",
        "name": "Narrowing of lung artery",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/pulmonary-artery-stenosis"
      },
      {
        "slug": "nasal-polyposis",
        "name": "Nasal polyposis",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/nasal-polyposis"
      },
      {
        "slug": "neonatal-respiratory-distress",
        "name": "Neonatal respiratory distress",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/neonatal-respiratory-distress"
      },
      {
        "slug": "airway-obstruction",
        "name": "Obstructive lung disease",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/airway-obstruction"
      },
      {
        "slug": "atelectasis",
        "name": "Partial or complete collapse of part or entire lung",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/atelectasis"
      },
      {
        "slug": "peribronchovascular-interstitial-thickening",
        "name": "Peribronchovascular interstitial thickening",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/peribronchovascular-interstitial-thickening"
      },
      {
        "slug": "bronchiectasis",
        "name": "Permanent enlargement of the airways of the lungs",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/bronchiectasis"
      },
      {
        "slug": "persistent-left-superior-vena-cava",
        "name": "Persistent left superior vena cava",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/persistent-left-superior-vena-cava"
      },
      {
        "slug": "pulmonary-situs-ambiguus",
        "name": "Pulmonary situs ambiguus",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/pulmonary-situs-ambiguus"
      },
      {
        "slug": "recurrent-otitis-media",
        "name": "Recurrent middle ear infection",
        "systems": [
          "abnormality-of-the-ear",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/recurrent-otitis-media"
      },
      {
        "slug": "recurrent-mycobacterial-infections",
        "name": "Recurrent mycobacterial infections",
        "systems": [
          "abnormality-of-the-immune-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/recurrent-mycobacterial-infections"
      },
      {
        "slug": "recurrent-pneumonia",
        "name": "Recurrent pneumonia",
        "systems": [
          "abnormality-of-the-immune-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/recurrent-pneumonia"
      },
      {
        "slug": "recurrent-respiratory-infections",
        "name": "Recurrent respiratory infections",
        "systems": [
          "abnormality-of-the-immune-system",
          "abnormality-of-the-respiratory-system"
        ],
        "url": "https://dantelabs.com/traits/recurrent-respiratory-infections"
      },
      {
        "slug": "recurrent-sinopulmonary-infections",
        "name": "Recurrent sinus and lung infections",
        "systems": [
          "abnormality-of-the-immune-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/recurrent-sinopulmonary-infections"
      },
      {
        "slug": "recurrent-sinusitis",
        "name": "Recurrent sinus disease",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-immune-system",
          "abnormality-of-the-musculoskeletal-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/recurrent-sinusitis"
      },
      {
        "slug": "respiratory-failure",
        "name": "Respiratory failure",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/respiratory-failure"
      },
      {
        "slug": "respiratory-insufficiency-due-to-defective-ciliary-clearance",
        "name": "Respiratory insufficiency due to defective ciliary clearance",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "url": "https://dantelabs.com/traits/respiratory-insufficiency-due-to-defective-ciliary-clearance"
      },
      {
        "slug": "respiratory-tract-infection",
        "name": "Respiratory tract infection",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/respiratory-tract-infection"
      },
      {
        "slug": "rod-cone-dystrophy",
        "name": "Rod-cone dystrophy",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/rod-cone-dystrophy"
      },
      {
        "slug": "rhinorrhea",
        "name": "Runny Nose",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "url": "https://dantelabs.com/traits/rhinorrhea"
      },
      {
        "slug": "hydrocephalus",
        "name": "Too much cerebrospinal fluid in the brain",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/hydrocephalus"
      },
      {
        "slug": "transposition-of-the-great-arteries",
        "name": "Transposition of the great arteries",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/transposition-of-the-great-arteries"
      },
      {
        "slug": "ventriculomegaly",
        "name": "Ventriculomegaly",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/ventriculomegaly"
      },
      {
        "slug": "productive-cough",
        "name": "Wet cough",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/productive-cough"
      },
      {
        "slug": "wheezing",
        "name": "Wheezing",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/wheezing"
      }
    ],
    "related": [
      {
        "slug": "ccdc39",
        "symbol": "CCDC39",
        "name": "coiled-coil domain 39 molecular ruler complex subunit",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/ccdc39"
      },
      {
        "slug": "ccdc40",
        "symbol": "CCDC40",
        "name": "coiled-coil domain 40 molecular ruler complex subunit",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/ccdc40"
      },
      {
        "slug": "ccno",
        "symbol": "CCNO",
        "name": "cyclin O",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/ccno"
      },
      {
        "slug": "cenpf",
        "symbol": "CENPF",
        "name": "centromere protein F",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cenpf"
      },
      {
        "slug": "cfap20dc",
        "symbol": "CFAP20DC",
        "name": "CFAP20 domain containing",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cfap20dc"
      },
      {
        "slug": "cfap221",
        "symbol": "CFAP221",
        "name": "cilia and flagella associated protein 221",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cfap221"
      },
      {
        "slug": "cfap298",
        "symbol": "CFAP298",
        "name": "cilia and flagella associated protein 298",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cfap298"
      },
      {
        "slug": "cfap300",
        "symbol": "CFAP300",
        "name": "cilia and flagella associated protein 300",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cfap300"
      },
      {
        "slug": "cfap54",
        "symbol": "CFAP54",
        "name": "cilia and flagella associated protein 54",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/cfap54"
      },
      {
        "slug": "clxn",
        "symbol": "CLXN",
        "name": "calaxin",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/clxn"
      },
      {
        "slug": "daw1",
        "symbol": "DAW1",
        "name": "dynein assembly factor with WD repeats 1",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/daw1"
      },
      {
        "slug": "dnaaf1",
        "symbol": "DNAAF1",
        "name": "dynein axonemal assembly factor 1",
        "shared": 1,
        "url": "https://dantelabs.com/no/genes/dnaaf1"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}