{
  "url": "https://dantelabs.com/traits/leiomyosarcoma",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "leiomyosarcoma",
    "id": "HP:0100243",
    "name": "Leiomyosarcoma",
    "definition": "A smooth muscle connective tissue tumor, which is rare type of cancer that is a malignant neoplasm of smooth muscle. When such a neoplasm is benign, it is called a leiomyoma.",
    "synonyms": [],
    "systems": [
      {
        "slug": "neoplasm",
        "name": "Abnormal tissue mass",
        "url": "https://dantelabs.com/traits/neoplasm"
      }
    ],
    "broader": [
      {
        "slug": "soft-tissue-sarcoma",
        "name": "Soft tissue sarcoma",
        "url": "https://dantelabs.com/traits/soft-tissue-sarcoma"
      }
    ],
    "narrower": [
      {
        "slug": "uterine-leiomyosarcoma",
        "name": "Uterine leiomyosarcoma",
        "genes": 28,
        "url": "https://dantelabs.com/traits/uterine-leiomyosarcoma"
      },
      {
        "slug": "cutaneous-leiomyosarcoma",
        "name": "Cutaneous leiomyosarcoma",
        "genes": 2,
        "url": "https://dantelabs.com/traits/cutaneous-leiomyosarcoma"
      }
    ],
    "genes": [
      {
        "slug": "sdha",
        "symbol": "SDHA",
        "hgnc": "HGNC:10680",
        "name": "succinate dehydrogenase complex flavoprotein subunit A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sdha"
      },
      {
        "slug": "sdhb",
        "symbol": "SDHB",
        "hgnc": "HGNC:10681",
        "name": "succinate dehydrogenase complex iron sulfur subunit B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sdhb"
      },
      {
        "slug": "sdhc",
        "symbol": "SDHC",
        "hgnc": "HGNC:10682",
        "name": "succinate dehydrogenase complex subunit C",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sdhc"
      }
    ]
  }
}