{
  "url": "https://dantelabs.com/traits/hypermagnesemia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hypermagnesemia",
    "id": "HP:0002918",
    "name": "High blood magnesium levels",
    "label": "Hypermagnesemia",
    "definition": "The concentration of magnesium in the blood circulation is above the upper limit of normal.",
    "synonyms": [
      "Elevated magnesium(2+) concentration",
      "Elevated magnesium(2+) level",
      "Elevated magnesium(2+) level in blood",
      "High blood Mg levels",
      "Increased magnesium(2+) concentration",
      "Increased magnesium(2+) level",
      "Increased magnesium(2+) level in blood"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-magnesium-concentration",
        "name": "Abnormal circulating magnesium concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-magnesium-concentration"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "casr",
        "symbol": "CASR",
        "hgnc": "HGNC:1514",
        "name": "calcium sensing receptor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/casr"
      },
      {
        "slug": "cldn10",
        "symbol": "CLDN10",
        "hgnc": "HGNC:2033",
        "name": "claudin 10",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cldn10"
      },
      {
        "slug": "gna11",
        "symbol": "GNA11",
        "hgnc": "HGNC:4379",
        "name": "G protein subunit alpha 11",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gna11"
      },
      {
        "slug": "aldob",
        "symbol": "ALDOB",
        "hgnc": "HGNC:417",
        "name": "aldolase, fructose-bisphosphate B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aldob"
      },
      {
        "slug": "clcnkb",
        "symbol": "CLCNKB",
        "hgnc": "HGNC:2027",
        "name": "chloride voltage-gated channel Kb",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/clcnkb"
      },
      {
        "slug": "slc12a3",
        "symbol": "SLC12A3",
        "hgnc": "HGNC:10912",
        "name": "solute carrier family 12 member 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc12a3"
      },
      {
        "slug": "ap2s1",
        "symbol": "AP2S1",
        "hgnc": "HGNC:565",
        "name": "adaptor related protein complex 2 subunit sigma 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ap2s1"
      }
    ]
  }
}