{
  "url": "https://dantelabs.com/traits/hyperamylasemia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hyperamylasemia",
    "id": "HP:0410288",
    "name": "Hyperamylasemia",
    "definition": "The concentration of amylase in the blood circulation is above the upper limit of normal.",
    "synonyms": [
      "Increased circulating amylase level"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-amylase-concentration",
        "name": "Abnormal circulating amylase concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-amylase-concentration"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "slc4a4",
        "symbol": "SLC4A4",
        "hgnc": "HGNC:11030",
        "name": "solute carrier family 4 member 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc4a4"
      },
      {
        "slug": "nek8",
        "symbol": "NEK8",
        "hgnc": "HGNC:13387",
        "name": "NIMA related kinase 8",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nek8"
      },
      {
        "slug": "nfs1",
        "symbol": "NFS1",
        "hgnc": "HGNC:15910",
        "name": "NFS1 cysteine desulfurase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nfs1"
      },
      {
        "slug": "nphp3",
        "symbol": "NPHP3",
        "hgnc": "HGNC:7907",
        "name": "nephrocystin 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nphp3"
      }
    ]
  }
}