{
  "url": "https://dantelabs.com/traits/flared-nostrils",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "flared-nostrils",
    "id": "HP:0000454",
    "name": "Flared nostrils",
    "synonyms": [
      "Flared nasal alae"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-morphology-of-the-nasal-alae",
        "name": "Abnormal morphology of the nasal alae",
        "url": "https://dantelabs.com/traits/abnormal-morphology-of-the-nasal-alae"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "tcf4",
        "symbol": "TCF4",
        "hgnc": "HGNC:11634",
        "name": "transcription factor 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tcf4"
      },
      {
        "slug": "ankrd17",
        "symbol": "ANKRD17",
        "hgnc": "HGNC:23575",
        "name": "ankyrin repeat domain 17",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ankrd17"
      },
      {
        "slug": "camta1",
        "symbol": "CAMTA1",
        "hgnc": "HGNC:18806",
        "name": "calmodulin binding transcription activator 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/camta1"
      },
      {
        "slug": "naa10",
        "symbol": "NAA10",
        "hgnc": "HGNC:18704",
        "name": "N-alpha-acetyltransferase 10, NatA catalytic subunit",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/naa10"
      },
      {
        "slug": "borcs8",
        "symbol": "BORCS8",
        "hgnc": "HGNC:37247",
        "name": "BLOC-1 related complex subunit 8",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/borcs8"
      },
      {
        "slug": "brcc3",
        "symbol": "BRCC3",
        "hgnc": "HGNC:24185",
        "name": "BRCA1/BRCA2-containing complex subunit 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brcc3"
      },
      {
        "slug": "cdc42",
        "symbol": "CDC42",
        "hgnc": "HGNC:1736",
        "name": "cell division cycle 42",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cdc42"
      },
      {
        "slug": "usp9x",
        "symbol": "USP9X",
        "hgnc": "HGNC:12632",
        "name": "ubiquitin specific peptidase 9 X-linked",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/usp9x"
      },
      {
        "slug": "pdha1",
        "symbol": "PDHA1",
        "hgnc": "HGNC:8806",
        "name": "pyruvate dehydrogenase E1 subunit alpha 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pdha1"
      },
      {
        "slug": "sin3a",
        "symbol": "SIN3A",
        "hgnc": "HGNC:19353",
        "name": "SIN3 transcription regulator family member A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sin3a"
      },
      {
        "slug": "smoc1",
        "symbol": "SMOC1",
        "hgnc": "HGNC:20318",
        "name": "SPARC related modular calcium binding 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smoc1"
      }
    ]
  }
}