{
  "url": "https://dantelabs.com/traits/dysphoria",
  "trait": {
    "bundleId": "2026.10.18-8b139e39",
    "release": "2026-09-01",
    "slug": "dysphoria",
    "id": "HP:0033838",
    "name": "Emotional discomfort",
    "label": "Dysphoria",
    "definition": "A pervasive state of negatively valenced emotional unease and dissatisfaction along with an inner discomfort that is disproportionate to external circumstances and may include heightened emotional reactivity. It is associated with a mixture of overlapping negative emotions that are difficult to disentangle.",
    "synonyms": [
      "Emotionally unsettled",
      "Feeling off inside",
      "Ill at ease"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "dysregulated-negative-emotional-state",
        "name": "Feeling bad",
        "url": "https://dantelabs.com/traits/dysregulated-negative-emotional-state"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "atp9a",
        "symbol": "ATP9A",
        "hgnc": "HGNC:13540",
        "name": "ATPase phospholipid transporting 9A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp9a"
      }
    ]
  }
}