{
  "url": "https://dantelabs.com/traits/abnormal-hemoglobin-concentration",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-hemoglobin-concentration",
    "id": "HP:0020061",
    "name": "Abnormal hemoglobin concentration",
    "definition": "Any deviation from the normal concentration of hemoglobin in the blood.",
    "synonyms": [
      "Abnormal haemoglobin concentration",
      "Abnormal Hb concentration"
    ],
    "systems": [
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-erythrocyte-morphology",
        "name": "Abnormal erythrocyte morphology",
        "url": "https://dantelabs.com/traits/abnormal-erythrocyte-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "increased-circulating-hemoglobin-concentration",
        "name": "Increased circulating hemoglobin concentration",
        "genes": 14,
        "url": "https://dantelabs.com/traits/increased-circulating-hemoglobin-concentration"
      },
      {
        "slug": "decreased-hemoglobin-concentration",
        "name": "Decreased hemoglobin concentration",
        "genes": 6,
        "url": "https://dantelabs.com/traits/decreased-hemoglobin-concentration"
      }
    ],
    "genes": [
      {
        "slug": "amn",
        "symbol": "AMN",
        "hgnc": "HGNC:14604",
        "name": "amnion associated transmembrane protein",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/amn"
      },
      {
        "slug": "cubn",
        "symbol": "CUBN",
        "hgnc": "HGNC:2548",
        "name": "cubilin",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cubn"
      }
    ]
  }
}