{
  "url": "https://dantelabs.com/traits/abnormal-circulating-iron-concentration",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-circulating-iron-concentration",
    "id": "HP:0040130",
    "name": "Abnormal circulating iron concentration",
    "definition": "The concentration of iron in the blood circulation is outside the limits of normal.",
    "synonyms": [
      "Abnormal serum iron concentration"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-iron-homeostasis",
        "name": "Abnormality of iron homeostasis",
        "url": "https://dantelabs.com/traits/abnormality-of-iron-homeostasis"
      }
    ],
    "narrower": [
      {
        "slug": "elevated-circulating-iron-concentration",
        "name": "Elevated circulating iron concentration",
        "genes": 14,
        "url": "https://dantelabs.com/traits/elevated-circulating-iron-concentration"
      },
      {
        "slug": "decreased-circulating-iron-concentration",
        "name": "Decreased circulating iron concentration",
        "genes": 8,
        "url": "https://dantelabs.com/traits/decreased-circulating-iron-concentration"
      }
    ],
    "genes": [
      {
        "slug": "piga",
        "symbol": "PIGA",
        "hgnc": "HGNC:8957",
        "name": "phosphatidylinositol glycan anchor biosynthesis class A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/piga"
      },
      {
        "slug": "ftl",
        "symbol": "FTL",
        "hgnc": "HGNC:3999",
        "name": "ferritin light chain",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ftl"
      }
    ]
  }
}