{
  "url": "https://dantelabs.com/nl/genes/hsf2bp",
  "gene": {
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    "symbol": "HSF2BP",
    "name": "heat shock transcription factor 2 binding protein",
    "hgnc": "HGNC:5226",
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    "location": "21q22.3",
    "locusType": "gene with protein product",
    "aliases": [
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    "previousSymbols": [],
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      "release": "v1.5",
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      "ensemblTranscript": "ENST00000291560.7",
      "refseqTranscript": "NM_007031.2",
      "ensemblProtein": "ENSP00000291560.2",
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        {
          "symbol": "U2AF1",
          "ensemblId": "ENSG00000160201",
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        {
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        {
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        {
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        {
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        },
        {
          "symbol": "CSTB",
          "ensemblId": "ENSG00000160213",
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          "strand": "-",
          "slug": "cstb"
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        {
          "symbol": "RRP1",
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        {
          "symbol": "AGPAT3",
          "ensemblId": "ENSG00000160216",
          "biotype": "protein_coding",
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          "slug": "agpat3"
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        {
          "symbol": "",
          "ensemblId": "ENSG00000288593",
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        {
          "symbol": "TRAPPC10",
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      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "female-infertility",
        "name": "Vrouwelijke onvruchtbaarheid",
        "diseases": [
          {
            "mondoId": "MONDO:0021124",
            "name": "Vrouwelijke onvruchtbaarheid",
            "genes": 37,
            "inheritance": null,
            "description": "Verminderd of afwezig vermogen van een vrouw om zwanger te worden.",
            "management": null,
            "evidence": {
              "gencc": [
                "PanelApp Australia"
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              "acmgSf": false,
              "inheritance": [
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            "sameAsReport": true,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/nl/conditions/female-infertility"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "premature-ovarian-insufficiency",
        "name": "Early menopause",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/premature-ovarian-insufficiency"
      },
      {
        "slug": "female-infertility",
        "name": "Female infertility",
        "systems": [
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        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/female-infertility"
      },
      {
        "slug": "irregular-menstruation",
        "name": "Menstrual irregularity",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/irregular-menstruation"
      },
      {
        "slug": "secondary-amenorrhea",
        "name": "Previous menstrual periods stop",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/secondary-amenorrhea"
      }
    ],
    "related": [
      {
        "slug": "ankrd31",
        "symbol": "ANKRD31",
        "name": "ankyrin repeat domain 31",
        "shared": 1,
        "url": "https://dantelabs.com/nl/genes/ankrd31"
      },
      {
        "slug": "atm",
        "symbol": "ATM",
        "name": "ATM serine/threonine kinase",
        "shared": 1,
        "url": "https://dantelabs.com/nl/genes/atm"
      },
      {
        "slug": "bmp15",
        "symbol": "BMP15",
        "name": "bone morphogenetic protein 15",
        "shared": 1,
        "url": "https://dantelabs.com/nl/genes/bmp15"
      },
      {
        "slug": "bnc1",
        "symbol": "BNC1",
        "name": "basonuclin zinc finger protein 1",
        "shared": 1,
        "url": "https://dantelabs.com/nl/genes/bnc1"
      },
      {
        "slug": "clpp",
        "symbol": "CLPP",
        "name": "caseinolytic mitochondrial matrix peptidase proteolytic subunit",
        "shared": 1,
        "url": "https://dantelabs.com/nl/genes/clpp"
      },
      {
        "slug": "cyp19a1",
        "symbol": "CYP19A1",
        "name": "cytochrome P450 family 19 subfamily A member 1",
        "shared": 1,
        "url": "https://dantelabs.com/nl/genes/cyp19a1"
      },
      {
        "slug": "fancm",
        "symbol": "FANCM",
        "name": "FA complementation group M",
        "shared": 1,
        "url": "https://dantelabs.com/nl/genes/fancm"
      },
      {
        "slug": "figla",
        "symbol": "FIGLA",
        "name": "folliculogenesis specific bHLH transcription factor",
        "shared": 1,
        "url": "https://dantelabs.com/nl/genes/figla"
      },
      {
        "slug": "fmr1",
        "symbol": "FMR1",
        "name": "fragile X messenger ribonucleoprotein 1",
        "shared": 1,
        "url": "https://dantelabs.com/nl/genes/fmr1"
      },
      {
        "slug": "foxl2",
        "symbol": "FOXL2",
        "name": "forkhead box L2",
        "shared": 1,
        "url": "https://dantelabs.com/nl/genes/foxl2"
      },
      {
        "slug": "fshr",
        "symbol": "FSHR",
        "name": "follicle stimulating hormone receptor",
        "shared": 1,
        "url": "https://dantelabs.com/nl/genes/fshr"
      },
      {
        "slug": "galt",
        "symbol": "GALT",
        "name": "galactose-1-phosphate uridylyltransferase",
        "shared": 1,
        "url": "https://dantelabs.com/nl/genes/galt"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}