{
  "url": "https://dantelabs.com/nl/genes/arhgap27",
  "gene": {
    "slug": "arhgap27",
    "symbol": "ARHGAP27",
    "name": "Rho GTPase activating protein 27",
    "hgnc": "HGNC:31813",
    "summary": null,
    "location": "17q21.31",
    "locusType": "gene with protein product",
    "aliases": [
      "CAMGAP1",
      "FLJ43547",
      "SH3P20"
    ],
    "previousSymbols": [
      "SH3D20"
    ],
    "ensemblId": "ENSG00000159314",
    "entrezId": 201176,
    "omim": [
      "610591"
    ],
    "uniprot": [
      "Q6ZUM4"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "17",
      "start": 45393908,
      "end": 45432870,
      "strand": "-",
      "ensemblTranscript": "ENST00000685559.1",
      "refseqTranscript": "NM_001282290.2",
      "ensemblProtein": "ENSP00000509127.1",
      "refseqProtein": "NP_001269219.1",
      "exons": [
        {
          "start": 45393908,
          "end": 45395633
        },
        {
          "start": 45395744,
          "end": 45395849
        },
        {
          "start": 45395983,
          "end": 45396117
        },
        {
          "start": 45396207,
          "end": 45396284
        },
        {
          "start": 45396487,
          "end": 45396585
        },
        {
          "start": 45396668,
          "end": 45396790
        },
        {
          "start": 45396916,
          "end": 45397024
        },
        {
          "start": 45397949,
          "end": 45398047
        },
        {
          "start": 45402714,
          "end": 45402818
        },
        {
          "start": 45403619,
          "end": 45403709
        },
        {
          "start": 45404029,
          "end": 45404096
        },
        {
          "start": 45404269,
          "end": 45404334
        },
        {
          "start": 45404445,
          "end": 45404528
        },
        {
          "start": 45404601,
          "end": 45404681
        },
        {
          "start": 45404924,
          "end": 45405106
        },
        {
          "start": 45405676,
          "end": 45406083
        },
        {
          "start": 45429623,
          "end": 45430297
        },
        {
          "start": 45431621,
          "end": 45431752
        },
        {
          "start": 45432216,
          "end": 45432349
        },
        {
          "start": 45432752,
          "end": 45432870
        }
      ],
      "cds": {
        "start": 45395456,
        "end": 45430279
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "17",
      "start": 43471275,
      "end": 43511787,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 44913389,
      "end": 45913388,
      "genes": [
        {
          "symbol": "GFAP",
          "ensemblId": "ENSG00000131095",
          "biotype": "protein_coding",
          "start": 44903159,
          "end": 44916937,
          "strand": "-",
          "slug": "gfap"
        },
        {
          "symbol": "KIF18B",
          "ensemblId": "ENSG00000186185",
          "biotype": "protein_coding",
          "start": 44924707,
          "end": 44947781,
          "strand": "-",
          "slug": "kif18b"
        },
        {
          "symbol": "NMT1",
          "ensemblId": "ENSG00000136448",
          "biotype": "protein_coding",
          "start": 44957992,
          "end": 45109016,
          "strand": "+",
          "slug": "nmt1"
        },
        {
          "symbol": "C1QL1",
          "ensemblId": "ENSG00000131094",
          "biotype": "protein_coding",
          "start": 44958933,
          "end": 44968369,
          "strand": "-",
          "slug": "c1ql1"
        },
        {
          "symbol": "DCAKD",
          "ensemblId": "ENSG00000172992",
          "biotype": "protein_coding",
          "start": 45023338,
          "end": 45061137,
          "strand": "-",
          "slug": "dcakd"
        },
        {
          "symbol": "PLCD3",
          "ensemblId": "ENSG00000161714",
          "biotype": "protein_coding",
          "start": 45108959,
          "end": 45133354,
          "strand": "-",
          "slug": "plcd3"
        },
        {
          "symbol": "ACBD4",
          "ensemblId": "ENSG00000181513",
          "biotype": "protein_coding",
          "start": 45132597,
          "end": 45144181,
          "strand": "+",
          "slug": "acbd4"
        },
        {
          "symbol": "HEXIM1",
          "ensemblId": "ENSG00000186834",
          "biotype": "protein_coding",
          "start": 45148475,
          "end": 45152099,
          "strand": "+",
          "slug": "hexim1"
        },
        {
          "symbol": "HEXIM2",
          "ensemblId": "ENSG00000168517",
          "biotype": "protein_coding",
          "start": 45160695,
          "end": 45170701,
          "strand": "+",
          "slug": "hexim2"
        },
        {
          "symbol": "FMNL1",
          "ensemblId": "ENSG00000184922",
          "biotype": "protein_coding",
          "start": 45220736,
          "end": 45247319,
          "strand": "+",
          "slug": "fmnl1"
        },
        {
          "symbol": "SPATA32",
          "ensemblId": "ENSG00000184361",
          "biotype": "protein_coding",
          "start": 45254388,
          "end": 45262116,
          "strand": "-",
          "slug": "spata32"
        },
        {
          "symbol": "MAP3K14",
          "ensemblId": "ENSG00000006062",
          "biotype": "protein_coding",
          "start": 45263119,
          "end": 45317112,
          "strand": "-",
          "slug": "map3k14"
        },
        {
          "symbol": "PLEKHM1",
          "ensemblId": "ENSG00000225190",
          "biotype": "protein_coding",
          "start": 45435900,
          "end": 45490986,
          "strand": "-",
          "slug": "plekhm1"
        },
        {
          "symbol": "LINC02210-CRHR1",
          "ensemblId": "ENSG00000263715",
          "biotype": "protein_coding",
          "start": 45620344,
          "end": 45835826,
          "strand": "+",
          "slug": "linc02210-crhr1"
        },
        {
          "symbol": "CRHR1",
          "ensemblId": "ENSG00000120088",
          "biotype": "protein_coding",
          "start": 45784277,
          "end": 45835828,
          "strand": "+",
          "slug": "crhr1"
        },
        {
          "symbol": "SPPL2C",
          "ensemblId": "ENSG00000185294",
          "biotype": "protein_coding",
          "start": 45844881,
          "end": 45847067,
          "strand": "+",
          "slug": "sppl2c"
        },
        {
          "symbol": "MAPT",
          "ensemblId": "ENSG00000186868",
          "biotype": "protein_coding",
          "start": 45894278,
          "end": 46028334,
          "strand": "+",
          "slug": "mapt"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}