{
  "url": "https://dantelabs.com/traits/undetectable-electroretinogram",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "undetectable-electroretinogram",
    "id": "HP:0000550",
    "name": "Undetectable electroretinogram",
    "definition": "Lack of any response to stimulation upon electroretinography.",
    "synonyms": [
      "Abolished electroretinogram",
      "Absent electroretinogram",
      "Extinction of electroretinogram",
      "Extinguished electroretinogram",
      "No light-evoked response on electroretinogram",
      "Undetectable ERG"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-electroretinogram",
        "name": "Abnormal electroretinogram",
        "url": "https://dantelabs.com/traits/abnormal-electroretinogram"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "cc2d2a",
        "symbol": "CC2D2A",
        "hgnc": "HGNC:29253",
        "name": "coiled-coil and C2 domain containing 2A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cc2d2a"
      },
      {
        "slug": "cln3",
        "symbol": "CLN3",
        "hgnc": "HGNC:2074",
        "name": "CLN3 lysosomal/endosomal transmembrane protein, battenin",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cln3"
      },
      {
        "slug": "crb1",
        "symbol": "CRB1",
        "hgnc": "HGNC:2343",
        "name": "crumbs cell polarity complex component 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/crb1"
      },
      {
        "slug": "crx",
        "symbol": "CRX",
        "hgnc": "HGNC:2383",
        "name": "cone-rod homeobox",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/crx"
      },
      {
        "slug": "dhdds",
        "symbol": "DHDDS",
        "hgnc": "HGNC:20603",
        "name": "dehydrodolichyl diphosphate synthase subunit",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dhdds"
      },
      {
        "slug": "fdxr",
        "symbol": "FDXR",
        "hgnc": "HGNC:3642",
        "name": "ferredoxin reductase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fdxr"
      },
      {
        "slug": "fsd1l",
        "symbol": "FSD1L",
        "hgnc": "HGNC:13753",
        "name": "fibronectin type III and SPRY domain containing 1 like",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fsd1l"
      },
      {
        "slug": "nmnat1",
        "symbol": "NMNAT1",
        "hgnc": "HGNC:17877",
        "name": "nicotinamide nucleotide adenylyltransferase 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/nmnat1"
      },
      {
        "slug": "pcyt1a",
        "symbol": "PCYT1A",
        "hgnc": "HGNC:8754",
        "name": "phosphate cytidylyltransferase 1A, choline",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pcyt1a"
      },
      {
        "slug": "tulp1",
        "symbol": "TULP1",
        "hgnc": "HGNC:12423",
        "name": "TUB like protein 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tulp1"
      },
      {
        "slug": "ubap1l",
        "symbol": "UBAP1L",
        "hgnc": "HGNC:40028",
        "name": "ubiquitin associated protein 1 like",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ubap1l"
      },
      {
        "slug": "abca4",
        "symbol": "ABCA4",
        "hgnc": "HGNC:34",
        "name": "ATP binding cassette subfamily A member 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/abca4"
      },
      {
        "slug": "alms1",
        "symbol": "ALMS1",
        "hgnc": "HGNC:428",
        "name": "ALMS1 centrosome and basal body associated protein",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alms1"
      },
      {
        "slug": "cabp4",
        "symbol": "CABP4",
        "hgnc": "HGNC:1386",
        "name": "calcium binding protein 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cabp4"
      },
      {
        "slug": "cln8",
        "symbol": "CLN8",
        "hgnc": "HGNC:2079",
        "name": "CLN8 transmembrane ER and ERGIC protein",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cln8"
      },
      {
        "slug": "hsd17b4",
        "symbol": "HSD17B4",
        "hgnc": "HGNC:5213",
        "name": "hydroxysteroid 17-beta dehydrogenase 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hsd17b4"
      },
      {
        "slug": "ift140",
        "symbol": "IFT140",
        "hgnc": "HGNC:29077",
        "name": "intraflagellar transport 140",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift140"
      },
      {
        "slug": "kcnj13",
        "symbol": "KCNJ13",
        "hgnc": "HGNC:6259",
        "name": "potassium inwardly rectifying channel subfamily J member 13",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnj13"
      },
      {
        "slug": "kiz",
        "symbol": "KIZ",
        "hgnc": "HGNC:15865",
        "name": "kizuna centrosomal protein",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiz"
      },
      {
        "slug": "lca5",
        "symbol": "LCA5",
        "hgnc": "HGNC:31923",
        "name": "lebercilin LCA5",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/lca5"
      },
      {
        "slug": "lrat",
        "symbol": "LRAT",
        "hgnc": "HGNC:6685",
        "name": "lecithin retinol acyltransferase",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/lrat"
      },
      {
        "slug": "nrl",
        "symbol": "NRL",
        "hgnc": "HGNC:8002",
        "name": "neural retina leucine zipper",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nrl"
      },
      {
        "slug": "otx2",
        "symbol": "OTX2",
        "hgnc": "HGNC:8522",
        "name": "orthodenticle homeobox 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/otx2"
      },
      {
        "slug": "pde6d",
        "symbol": "PDE6D",
        "hgnc": "HGNC:8788",
        "name": "phosphodiesterase 6D",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pde6d"
      },
      {
        "slug": "prph2",
        "symbol": "PRPH2",
        "hgnc": "HGNC:9942",
        "name": "peripherin 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prph2"
      },
      {
        "slug": "rpe65",
        "symbol": "RPE65",
        "hgnc": "HGNC:10294",
        "name": "retinoid isomerohydrolase RPE65",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rpe65"
      },
      {
        "slug": "spata7",
        "symbol": "SPATA7",
        "hgnc": "HGNC:20423",
        "name": "spermatogenesis associated 7",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spata7"
      },
      {
        "slug": "clcc1",
        "symbol": "CLCC1",
        "hgnc": "HGNC:29675",
        "name": "chloride channel CLIC like 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/clcc1"
      },
      {
        "slug": "eys",
        "symbol": "EYS",
        "hgnc": "HGNC:21555",
        "name": "EGF-like photoreceptor maintenance factor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eys"
      },
      {
        "slug": "flvcr1",
        "symbol": "FLVCR1",
        "hgnc": "HGNC:24682",
        "name": "FLVCR choline and heme transporter 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flvcr1"
      },
      {
        "slug": "myo7a",
        "symbol": "MYO7A",
        "hgnc": "HGNC:7606",
        "name": "myosin VIIA",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myo7a"
      },
      {
        "slug": "nr2e3",
        "symbol": "NR2E3",
        "hgnc": "HGNC:7974",
        "name": "nuclear receptor subfamily 2 group E member 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nr2e3"
      },
      {
        "slug": "pomgnt1",
        "symbol": "POMGNT1",
        "hgnc": "HGNC:19139",
        "name": "protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pomgnt1"
      },
      {
        "slug": "ppt1",
        "symbol": "PPT1",
        "hgnc": "HGNC:9325",
        "name": "palmitoyl-protein thioesterase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppt1"
      },
      {
        "slug": "prcd",
        "symbol": "PRCD",
        "hgnc": "HGNC:32528",
        "name": "photoreceptor disc component",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prcd"
      },
      {
        "slug": "prom1",
        "symbol": "PROM1",
        "hgnc": "HGNC:9454",
        "name": "prominin 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prom1"
      },
      {
        "slug": "rpgrip1",
        "symbol": "RPGRIP1",
        "hgnc": "HGNC:13436",
        "name": "RPGR interacting protein 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rpgrip1"
      },
      {
        "slug": "tpp1",
        "symbol": "TPP1",
        "hgnc": "HGNC:2073",
        "name": "tripeptidyl peptidase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tpp1"
      },
      {
        "slug": "ush1c",
        "symbol": "USH1C",
        "hgnc": "HGNC:12597",
        "name": "USH1 protein network component harmonin",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ush1c"
      }
    ]
  }
}