{
  "url": "https://dantelabs.com/traits/isometric-tremor",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "isometric-tremor",
    "id": "HP:0030185",
    "name": "Isometric tremor",
    "definition": "An isometric tremor occurs with muscle contraction against a rigid stationary object (e.g., when making a fist).",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "action-tremor",
        "name": "Action tremor",
        "url": "https://dantelabs.com/traits/action-tremor"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "rnu2-2",
        "symbol": "RNU2-2",
        "hgnc": "HGNC:10152",
        "name": "RNA, U2 small nuclear 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu2-2"
      },
      {
        "slug": "sptbn1",
        "symbol": "SPTBN1",
        "hgnc": "HGNC:11275",
        "name": "spectrin beta, non-erythrocytic 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sptbn1"
      }
    ]
  }
}