{
  "url": "https://dantelabs.com/traits/hypocystinemia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hypocystinemia",
    "id": "HP:0500152",
    "name": "Decreased blood cystine concentration",
    "label": "Hypocystinemia",
    "definition": "The concentration of cystine in the blood circulation is below the lower limit of normal.",
    "synonyms": [
      "Low blood cystine levels",
      "Decreased cystine concentration",
      "Decreased cystine level",
      "Decreased cystine level in blood",
      "Reduced cystine concentration",
      "Reduced cystine level",
      "Reduced cystine level in blood"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-cysteine-concentration",
        "name": "Abnormal circulating cysteine concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-cysteine-concentration"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "gphn",
        "symbol": "GPHN",
        "hgnc": "HGNC:15465",
        "name": "gephyrin",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gphn"
      },
      {
        "slug": "nfe2l2",
        "symbol": "NFE2L2",
        "hgnc": "HGNC:7782",
        "name": "NFE2 like bZIP transcription factor 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nfe2l2"
      }
    ]
  }
}