{
  "url": "https://dantelabs.com/traits/hypervalinemia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hypervalinemia",
    "id": "HP:0010910",
    "name": "High blood valine concentration",
    "label": "Hypervalinemia",
    "definition": "The concentration of valine in the blood circulation is above the upper limit of normal.",
    "synonyms": [
      "Elevated valine concentration",
      "Elevated valine level",
      "Elevated valine level in blood",
      "Increased valine concentration",
      "Increased valine level",
      "Increased valine level in blood"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-valine-concentration",
        "name": "Abnormal circulating valine concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-valine-concentration"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "atp5f1b",
        "symbol": "ATP5F1B",
        "hgnc": "HGNC:830",
        "name": "ATP synthase F1 subunit beta",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp5f1b"
      },
      {
        "slug": "bcat2",
        "symbol": "BCAT2",
        "hgnc": "HGNC:977",
        "name": "branched chain amino acid transaminase 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bcat2"
      },
      {
        "slug": "bckdhb",
        "symbol": "BCKDHB",
        "hgnc": "HGNC:987",
        "name": "branched chain keto acid dehydrogenase E1 subunit beta",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bckdhb"
      },
      {
        "slug": "micu1",
        "symbol": "MICU1",
        "hgnc": "HGNC:1530",
        "name": "mitochondrial calcium uptake 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/micu1"
      }
    ]
  }
}