{
  "url": "https://dantelabs.com/traits/hyperplastic-callus-formation",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hyperplastic-callus-formation",
    "id": "HP:0030268",
    "name": "Hyperplastic callus formation",
    "definition": "Increased growth of callus, the bony and cartilaginous material that forms a connecting bridge across a bone fracture during fracture healing.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-skeletal-morphology",
        "name": "Abnormally shaped skeletal",
        "url": "https://dantelabs.com/traits/abnormal-skeletal-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "krt16",
        "symbol": "KRT16",
        "hgnc": "HGNC:6423",
        "name": "keratin 16",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/krt16"
      },
      {
        "slug": "krt17",
        "symbol": "KRT17",
        "hgnc": "HGNC:6427",
        "name": "keratin 17",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/krt17"
      },
      {
        "slug": "krt6a",
        "symbol": "KRT6A",
        "hgnc": "HGNC:6443",
        "name": "keratin 6A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/krt6a"
      },
      {
        "slug": "krt6b",
        "symbol": "KRT6B",
        "hgnc": "HGNC:6444",
        "name": "keratin 6B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/krt6b"
      },
      {
        "slug": "ifitm5",
        "symbol": "IFITM5",
        "hgnc": "HGNC:16644",
        "name": "interferon induced transmembrane protein 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ifitm5"
      }
    ]
  }
}