{
  "url": "https://dantelabs.com/traits/fasting-hypoglycemia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "fasting-hypoglycemia",
    "id": "HP:0003162",
    "name": "Low blood sugar when fasting",
    "label": "Fasting hypoglycemia",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "hypoglycemia",
        "name": "Low blood sugar",
        "url": "https://dantelabs.com/traits/hypoglycemia"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "g6pc1",
        "symbol": "G6PC1",
        "hgnc": "HGNC:4056",
        "name": "glucose-6-phosphatase catalytic subunit 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/g6pc1"
      },
      {
        "slug": "slc2a2",
        "symbol": "SLC2A2",
        "hgnc": "HGNC:11006",
        "name": "solute carrier family 2 member 2",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/slc2a2"
      },
      {
        "slug": "abcc8",
        "symbol": "ABCC8",
        "hgnc": "HGNC:59",
        "name": "ATP binding cassette subfamily C member 8",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/abcc8"
      },
      {
        "slug": "hnf4a",
        "symbol": "HNF4A",
        "hgnc": "HGNC:5024",
        "name": "hepatocyte nuclear factor 4 alpha",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hnf4a"
      },
      {
        "slug": "iars2",
        "symbol": "IARS2",
        "hgnc": "HGNC:29685",
        "name": "isoleucyl-tRNA synthetase 2, mitochondrial",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/iars2"
      },
      {
        "slug": "insr",
        "symbol": "INSR",
        "hgnc": "HGNC:6091",
        "name": "insulin receptor",
        "frequency": "very-frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/insr"
      },
      {
        "slug": "kcnj11",
        "symbol": "KCNJ11",
        "hgnc": "HGNC:6257",
        "name": "potassium inwardly rectifying channel subfamily J member 11",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnj11"
      },
      {
        "slug": "slc25a20",
        "symbol": "SLC25A20",
        "hgnc": "HGNC:1421",
        "name": "solute carrier family 25 member 20",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc25a20"
      },
      {
        "slug": "akt2",
        "symbol": "AKT2",
        "hgnc": "HGNC:392",
        "name": "AKT serine/threonine kinase 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/akt2"
      },
      {
        "slug": "fbp1",
        "symbol": "FBP1",
        "hgnc": "HGNC:3606",
        "name": "fructose-bisphosphatase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fbp1"
      },
      {
        "slug": "grb10",
        "symbol": "GRB10",
        "hgnc": "HGNC:4564",
        "name": "growth factor receptor bound protein 10",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/grb10"
      },
      {
        "slug": "hnf1a",
        "symbol": "HNF1A",
        "hgnc": "HGNC:11621",
        "name": "HNF1 homeobox A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hnf1a"
      },
      {
        "slug": "phka2",
        "symbol": "PHKA2",
        "hgnc": "HGNC:8926",
        "name": "phosphorylase kinase regulatory subunit alpha 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/phka2"
      },
      {
        "slug": "phkb",
        "symbol": "PHKB",
        "hgnc": "HGNC:8927",
        "name": "phosphorylase kinase regulatory subunit beta",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/phkb"
      },
      {
        "slug": "phkg2",
        "symbol": "PHKG2",
        "hgnc": "HGNC:8931",
        "name": "phosphorylase kinase catalytic subunit gamma 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/phkg2"
      },
      {
        "slug": "gcdh",
        "symbol": "GCDH",
        "hgnc": "HGNC:4189",
        "name": "glutaryl-CoA dehydrogenase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gcdh"
      },
      {
        "slug": "secisbp2",
        "symbol": "SECISBP2",
        "hgnc": "HGNC:30972",
        "name": "SECIS binding protein 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/secisbp2"
      },
      {
        "slug": "gys2",
        "symbol": "GYS2",
        "hgnc": "HGNC:4707",
        "name": "glycogen synthase 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gys2"
      },
      {
        "slug": "igf2",
        "symbol": "IGF2",
        "hgnc": "HGNC:5466",
        "name": "insulin like growth factor 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/igf2"
      },
      {
        "slug": "pck1",
        "symbol": "PCK1",
        "hgnc": "HGNC:8724",
        "name": "phosphoenolpyruvate carboxykinase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pck1"
      },
      {
        "slug": "slc1a1",
        "symbol": "SLC1A1",
        "hgnc": "HGNC:10939",
        "name": "solute carrier family 1 member 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc1a1"
      },
      {
        "slug": "tbx19",
        "symbol": "TBX19",
        "hgnc": "HGNC:11596",
        "name": "T-box transcription factor 19",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbx19"
      }
    ]
  }
}