{
  "url": "https://dantelabs.com/traits/dense-calvaria",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "dense-calvaria",
    "id": "HP:0000250",
    "name": "Dense skull cap",
    "label": "Dense calvaria",
    "definition": "An abnormal increase of density of the bones making up the calvaria.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-calvaria-morphology",
        "name": "Abnormality of cranium",
        "url": "https://dantelabs.com/traits/abnormal-calvaria-morphology"
      },
      {
        "slug": "increased-skull-ossification",
        "name": "Increased calcification of skull",
        "url": "https://dantelabs.com/traits/increased-skull-ossification"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "hgsnat",
        "symbol": "HGSNAT",
        "hgnc": "HGNC:26527",
        "name": "heparan-alpha-glucosaminide N-acetyltransferase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hgsnat"
      },
      {
        "slug": "naglu",
        "symbol": "NAGLU",
        "hgnc": "HGNC:7632",
        "name": "N-acetyl-alpha-glucosaminidase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/naglu"
      },
      {
        "slug": "sgsh",
        "symbol": "SGSH",
        "hgnc": "HGNC:10818",
        "name": "N-sulfoglucosamine sulfohydrolase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sgsh"
      }
    ]
  }
}