{
  "url": "https://dantelabs.com/traits/cutaneous-anergy",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "cutaneous-anergy",
    "id": "HP:0002965",
    "name": "Cutaneous anergy",
    "definition": "Inability to react to a delayed hypersensitivity skin test.",
    "synonyms": [
      "Absence of delayed hypersensitivity skin test",
      "Lack of delayed skin hypersensitivity reaction"
    ],
    "systems": [
      {
        "slug": "abnormal-cellular-phenotype",
        "name": "Abnormal cellular phenotype",
        "url": "https://dantelabs.com/traits/abnormal-cellular-phenotype"
      },
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      },
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-delayed-hypersensitivity-skin-test",
        "name": "Abnormal delayed hypersensitivity skin test",
        "url": "https://dantelabs.com/traits/abnormal-delayed-hypersensitivity-skin-test"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "ciita",
        "symbol": "CIITA",
        "hgnc": "HGNC:7067",
        "name": "class II major histocompatibility complex transactivator",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ciita"
      },
      {
        "slug": "epg5",
        "symbol": "EPG5",
        "hgnc": "HGNC:29331",
        "name": "ectopic P-granules 5 autophagy tethering factor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/epg5"
      },
      {
        "slug": "jak3",
        "symbol": "JAK3",
        "hgnc": "HGNC:6193",
        "name": "Janus kinase 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/jak3"
      }
    ]
  }
}