{
  "url": "https://dantelabs.com/traits/abnormal-alpha-granule-content",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-alpha-granule-content",
    "id": "HP:0012527",
    "name": "Abnormal alpha granule content",
    "definition": "A deviation from the normal contents of the platelet alpha granules, which normally contain hemostatic proteins such as fibrinogen, von Willebrand factor, and growth factors such as platelet-derived growth factor.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-alpha-granules",
        "name": "Abnormal alpha granules",
        "url": "https://dantelabs.com/traits/abnormal-alpha-granules"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "runx1",
        "symbol": "RUNX1",
        "hgnc": "HGNC:10471",
        "name": "RUNX family transcription factor 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/runx1"
      }
    ]
  }
}