{
  "url": "https://dantelabs.com/lt/genes/tomm7",
  "gene": {
    "slug": "tomm7",
    "symbol": "TOMM7",
    "name": "translocase of outer mitochondrial membrane 7",
    "hgnc": "HGNC:21648",
    "summary": null,
    "location": "7p15.3",
    "locusType": "gene with protein product",
    "aliases": [
      "Tom7"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000196683",
    "entrezId": 54543,
    "omim": [
      "607980"
    ],
    "uniprot": [
      "Q9P0U1"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "7",
      "start": 22812974,
      "end": 22822849,
      "strand": "-",
      "ensemblTranscript": "ENST00000358435.9",
      "refseqTranscript": "NM_019059.5",
      "ensemblProtein": "ENSP00000351214.4",
      "refseqProtein": "NP_061932.1",
      "exons": [
        {
          "start": 22812974,
          "end": 22813185
        },
        {
          "start": 22818000,
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        },
        {
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        }
      ],
      "cds": {
        "start": 22813170,
        "end": 22822779
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "7",
      "start": 22852251,
      "end": 22862470,
      "strand": "-"
    },
    "neighbourhood": {
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      "end": 23317911,
      "genes": [
        {
          "symbol": "RAPGEF5",
          "ensemblId": "ENSG00000136237",
          "biotype": "protein_coding",
          "start": 22117700,
          "end": 22357170,
          "strand": "-",
          "slug": "rapgef5"
        },
        {
          "symbol": "STEAP1B",
          "ensemblId": "ENSG00000105889",
          "biotype": "protein_coding",
          "start": 22416932,
          "end": 22727789,
          "strand": "-",
          "slug": "steap1b"
        },
        {
          "symbol": "IL6",
          "ensemblId": "ENSG00000136244",
          "biotype": "protein_coding",
          "start": 22725884,
          "end": 22732002,
          "strand": "+",
          "slug": "il6"
        },
        {
          "symbol": "HYCC1",
          "ensemblId": "ENSG00000122591",
          "biotype": "protein_coding",
          "start": 22889371,
          "end": 23014148,
          "strand": "-",
          "slug": "hycc1"
        },
        {
          "symbol": "KLHL7",
          "ensemblId": "ENSG00000122550",
          "biotype": "protein_coding",
          "start": 23105729,
          "end": 23177914,
          "strand": "+",
          "slug": "klhl7"
        },
        {
          "symbol": "NUP42",
          "ensemblId": "ENSG00000136243",
          "biotype": "protein_coding",
          "start": 23181804,
          "end": 23201011,
          "strand": "+",
          "slug": "nup42"
        },
        {
          "symbol": "GPNMB",
          "ensemblId": "ENSG00000136235",
          "biotype": "protein_coding",
          "start": 23235967,
          "end": 23275111,
          "strand": "+",
          "slug": "gpnmb"
        },
        {
          "symbol": "MALSU1",
          "ensemblId": "ENSG00000156928",
          "biotype": "protein_coding",
          "start": 23298739,
          "end": 23311729,
          "strand": "+",
          "slug": "malsu1"
        },
        {
          "symbol": "IGF2BP3",
          "ensemblId": "ENSG00000136231",
          "biotype": "protein_coding",
          "start": 23308571,
          "end": 23470833,
          "strand": "-",
          "slug": "igf2bp3"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "microphthalmia",
        "name": "Abnormally small eyeball",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/microphthalmia"
      },
      {
        "slug": "cafe-au-lait-spot",
        "name": "Birthmark",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/cafe-au-lait-spot"
      },
      {
        "slug": "broad-forehead",
        "name": "Broad forehead",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/broad-forehead"
      },
      {
        "slug": "broad-palm",
        "name": "Broad palm",
        "systems": [
          "abnormality-of-limbs"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/broad-palm"
      },
      {
        "slug": "bulbous-nose",
        "name": "Bulbous nose",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/bulbous-nose"
      },
      {
        "slug": "coxa-valga",
        "name": "Coxa valga",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/coxa-valga"
      },
      {
        "slug": "reduced-visual-acuity",
        "name": "Decreased clarity of vision",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/reduced-visual-acuity"
      },
      {
        "slug": "dental-crowding",
        "name": "Dental crowding",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/dental-crowding"
      },
      {
        "slug": "secondary-microcephaly",
        "name": "Development of small head that was not present at birth",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/secondary-microcephaly"
      },
      {
        "slug": "platyspondyly",
        "name": "Flattened vertebrae",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/platyspondyly"
      },
      {
        "slug": "postnatal-growth-retardation",
        "name": "Growth delay as children",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/postnatal-growth-retardation"
      },
      {
        "slug": "increased-circulating-lactate-dehydrogenase-concentration",
        "name": "Increased circulating lactate dehydrogenase concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/increased-circulating-lactate-dehydrogenase-concentration"
      },
      {
        "slug": "nystagmus",
        "name": "Involuntary, rapid, rhythmic eye movements",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/nystagmus"
      },
      {
        "slug": "micrognathia",
        "name": "Little lower jaw",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/micrognathia"
      },
      {
        "slug": "hypotonia",
        "name": "Low muscle tone",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/hypotonia"
      },
      {
        "slug": "microvesicular-hepatic-steatosis",
        "name": "Microvesicular hepatic steatosis",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/microvesicular-hepatic-steatosis"
      },
      {
        "slug": "narrow-chest",
        "name": "Narrow chest",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/narrow-chest"
      },
      {
        "slug": "ovoid-vertebral-bodies",
        "name": "Ovoid vertebral bodies",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/ovoid-vertebral-bodies"
      },
      {
        "slug": "persistent-open-anterior-fontanelle",
        "name": "Persistent open anterior fontanelle",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/persistent-open-anterior-fontanelle"
      },
      {
        "slug": "prominent-nasal-bridge",
        "name": "Prominent nasal bridge",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/prominent-nasal-bridge"
      },
      {
        "slug": "high-hypermetropia",
        "name": "Severe farsightedness",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/high-hypermetropia"
      },
      {
        "slug": "short-stature",
        "name": "Short stature",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/short-stature"
      },
      {
        "slug": "slender-long-bone",
        "name": "Slender long bone",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/slender-long-bone"
      },
      {
        "slug": "slender-metacarpals",
        "name": "Slender long bones of hand",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/slender-metacarpals"
      },
      {
        "slug": "small-nail",
        "name": "Small nail",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/small-nail"
      },
      {
        "slug": "sparse-hair",
        "name": "Sparse hair",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/sparse-hair"
      },
      {
        "slug": "thin-ribs",
        "name": "Thin ribs",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/thin-ribs"
      },
      {
        "slug": "triangular-face",
        "name": "Triangular face",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/triangular-face"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}